Ligand Hg2+

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Basic Ligand Information

Molecular Structure
Picture of Hg2+ (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Hg
Hg2+
BQPIGGFYSBELGY-UHFFFAOYSA-N
Synonyms:
cationic mercury, Mercury(2+)


Show all pahtways known for Show all BRENDA pathways known for Hg2+

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
ATP + H2O + Hg2+/in = ADP + phosphate + Hg2+/out
-

Product in Enzyme-catalyzed Reactions (83 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
ATP + H2O + Hg2+/in = ADP + phosphate + Hg2+/out
-

Activator in Enzyme-catalyzed Reactions (4 results)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (3227 results)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
1 mM, 63% of initial activity
-
100 mM, 33% of initial activity
-
no effect
-
0.064 mM, activity is completely blocked
-
0.25 mM, complete inhibition, 0.05 mM, 95% inhibition
-
0.5 mM, 100% inhibition of wild-type and C38D mutant enzyme
-
L-carnitine dehydrogenase, complete inhibition
-
complete inhibition at 1 mM
-
complete inhibition
-
complete inhibition at 1 mM
-
90% inhibition of D-mannitol oxidation at 1 mM
-
complete inhibition at 1 mM
-
0.005 mM, complete inhibition, prevented by 10 mM glutathione
-
40% inhibition of NAD dehydrogenase II at 0.004 mM
-
53% inhibition at 0.002 mM
-
IC50 0.00009 mM
-
irreversible inactivation
-
complete inhibition at 0.01 mM
-
complete inhibition at 1 mM
-
complete inhibition at 2 mM
-
50% inhibition at 0.01 mM
-
complete inhibition at 2 mM
-
strong inhibition
-
nearly complete inhibition at 2 mM
-
1 mM, complete inhibition
-
100% inhibition
-
complete inhibition at 1 mM
99% inactivation at 1 mM
-
almost complete inhibition at 0.25 mM
complete inhibition
-
slight inhibition
-
strong inhibitor
-
1 mM, less than 10% residual activity
-
0.1 mM, complete inhibition
-
D-carnitine dehydrogenase, 0.01 mM, complete inhibition
-
D-carnitine dehydrogenase, 1 mM, complete inactivation
-
strong
-
1 mM, 90% inhibition
-
1 mM, complete inhibition
-
NADH protects more effectively than NAD+
-
inhibition at 1 mM, and destabilization at 10 mM
-
2 mM, complete inactivation
-
complete inhibition at 0.1 mM
-
0.001 mM, 2 min, complete inhibition
-
complete inhibition at 1 mM
-
0.1 mM, complete inhibition
-
complete inhibition at 0.1 mM
-
completely inhibits reduction of 2-dehydropantolactone
-
0.0005 mM, almost complete inhibition
-
HgCl2
-
1 mM, 85% inhibition
-
1 mM, complete inhibition
-
1 mM, 47% inhibition, G6PDH-2; 1 mM, 84% inhibition, G6PDH-1
-
1 mM, complete inhibition
-
noncompetitive inhibition
-
10-20% inhibition
-
complete inhibition at 1 mM
-
protection by NAD+
-
1 mM, 97% inhibition
-
100% inhibition at 5 mM; 5 mM, 100% inhibition
-
30% inhibition at 1 mM
-
0.1 mM, complete inhibition
-
67% inhibition at 1 mM
complete inhibition
-
1 mM, complete inhibition
-
strong inhibition at 1 mM
-
strong inhibitor
-
at 1 mM
-
completely inhibits at 10 mM
-
strong inhibitor
-
0.1 mM HgCl2 complete inhibition
-
0.1 mM, complete inhibition
-
1 mM HgCl2, 30 min, strong
-
52% residual activity at 0.5 mM
-
reversible by mercaptoethanol
-
strong inhibition of intra- and extracellular enzymes
-
94% inhibition at 1 mM
-
weak inhibition
-
1 mM, 93% inhibition
-
22% inhibition at 2 mM
-
35% residual activity at 1 mM
-
93% inhibition at 2 mM
-
90% inhibition at 1 mM
-
complete inhibition at 0.1 mM
-
inhibits 21.8% at 5 mM
-
markedly inhibited by Hg2+
-
markedly inhibited by HgCl2
-
0.1 mM concentration 98% inhibition
-
60% inhibition at 1 mM
-
1 mM, complete inhibition
-
complete inhibition at 2 mM
-
2% residual activity at 1 mM
-
2 mM, 20% inhibition after 6 h
at 1 mM
-
at 1 mM; competitive
-
100% inhibition at 1 mM
-
strong
-
100% inhibition at 0.1 mM
-
1 mM, 84% inhibition
-
1 mM, 4% inhibition
1 mM, 46% inhibition
1 mM, 50% inhibition
1 mM, 93% of inhibition
1.0 mM, 48% loss of activity
14% inhibition at 1 mM
5 mM, 90% loss of activity
7.4% residual activity at 5 mM
concentration-dependent inhibition up to 1 mM
inhibits 17.2% at 1 mM
significantly inhibition
strong
strong inhibition
strong inhibition at 1 mM
0.01 mM, appreciable inhibition
-
56% inhibition at 0.5 mM
-
complete inhibition at 20 mM
-
21% inhibition at 0.01 mM
-
complete inhibition at 1 mM
inhibition of NADH oxidizing activity
-
10 mM, 14% residual activity
-
1 mM, slight inhibtion
-
41% relative activity at 1 mM; 50% inhibition at 1 mM; 50% relative activity at 1 mM; 59% inhibition at 1 mM
-
5 mM, 17% residual activity
-
80% inhibition at 5 mM, at 37°C
-
complete inhibition at 10 mM
-
complete inhibition at 1 mM
-
inhibition can almost completely reserved by addition of glutathione
inhibits Oep1LOX2 by 60% and totally inactivates Oep2LOX2
-
0.5 mM HgCl2, 30% inhibition
-
0.5 mM, slight inhibition
-
complete inhibition at 1 mM
-
0.1 mM, 45% inhibition
-
1 mM, complete inhibition
-
2 mM, complete inhibition
-
5 mM, more than 95% inhibition
-
strong inhibition
-
inhibition reversed by glutathione
-
blocks cysteines in the active site pocket
1 mM, 87% loss of activity
-
0.4 mM, 96% inhibition
-
0.5 mM, strong
-
causes a 20-30% fall in activity
-
50% inhibition at 0.005 mM
-
1 mM, 98% inhibition
-
0.01-0.1 mM, 96% loss of activity
-
1 mM, about 5% residual activity
-
0.1 mM HgCl2, complete inhibition
-
0.1 mM, complete loss of activity
-
85% inhibition at 0.01 mM, inhibition can be reversed by thiol reagents
-
complete inhibition at 0.05 mM
-
inhibition at 0.02 mM, partially reversed by 2-mercaptoethanol
-
0.1 mM, 87% inhibition
-
complete inhibition at 0.01 mM
-
complete inhibition at 0.1 mM
-
63% inhibition at 1 mM, crude enzyme extract
-
complete inhibition at 5 mM
-
87% inhibition at 0.1 mM
-
0.3 mM, complete inhibition
-
inhibition of NADPH-cytochrome c reductase or biliverdin reductase in reconstituted heme oxygenase system
-
complete inhibition at 1 mM
-
0.001-0.01 mM, complete inhibition
-
0.005 mM, 70% inhibition
-
severely inhibits enzyme activity
-
0.1 mM concentration, 100% inhibition
-
0.0001 mM, 56% inhibition
-
Hg2+ causes an inhibition in the range of 13% and 72% at 1 and 10 mM, respectively
-
inhibition of tyrosine hydroxylation
-
strongly inhibited diphenolase activity at ripening stage 1 and 2
-
slight inhibition
-
DELTA12-desaturase system, enzymatic complex
-
0.4 mM, 96% inhibition
-
35% inhibition at 0.1 mM, complete inhibition at 5 mM
-
inhibits by 35% at 10 mM
-
strong inhibition
-
pronounced substrate inhibition
slight inhibition of the ATII-LCL enzyme
0.77% residual activity at 1.0 mM
-
complete inhibition of hypoxanthine oxidation at 0.1 mM
-
1 mM, complete inhibition
-
98% inhibition at 1 mM; 98% inhibition at 1 mM
-
strong inhibition
-
95% inhibition at 1 mM
-
strong inhibitor
-
complete inhibition at 10 mM
strong inhibition
62% inhibition at 1 mM
-
almost complete inhibition at 1 mM HgCl2
-
complete inhibition at 1 mM
-
0.2 mM, almost complete inhibition
-
77% inhibition in the presence of 1 mM
-
0.5 mM HgCl2, complete inhibition, irreversible
-
complete inhibition at 2 mM
-
0.05 mM causes 28% inhibition at 30°C
-
1 mM causes complete inhibition
-
100% inhibition at 1 mM; 1 mM, 100% inhibition
-
complete inhibition at 0.25 mM
-
1 mM, 17.5% inhibition
-
0.0001-0.0005 mM HgCl2
-
3 mM HgCl2, 90-100% inhibition
-
complete inhibition at 1 mM
-
both isoforms
-
1 mM, 12 h, 4°C, 99% loss of activity
-
1 mM, complete inhibition
-
mM concentration
-
strong inhibitor, 4% residual activity at 2 mM Hg2+
-
complete inhibition at 2 mM
-
complete inhibition of both orotate reductase and NADH oxidase reaction
-
1 mM, 86% inhibition
-
0.1 mM, 92% inhibition
-
depending on concentration it can react with any component of the NADPH:PChlide oxidoreductase macrodomains
-
inhibitor causes seripous alterations of the enzyme structure resulting in the trans-localisation of NADPH within the active site pf POR
-
complete inhibition at 1 mM
-
87% inhibition at 1 mM
-
acts comparably on wild-type and mutant N272H
-
1 mM, 97% inhibition
-
completely inhibits at 0.1 mM
-
0.1 mM, complete inhibition
-
1 mM, 61% inhibition of the recombinant enzyme
-
1 mM, complete loss of activtiy for wild-type. 8fold increase in activity for mutant C1141T
-
no activity in the presence of 1 mM Hg2+
-
0.1 mM, strong inhibition
-
HgCl2: 0.01 mM, 91% loss of activity
-
1 mM, 76% residual activity
-
at 0.1 mM, complete activity loss
-
at 1 mM, 10% inhibition
-
at 1 mM, 100% activity loss
-
at 1 mM, 70% inhibition
-
HgCl2: strong inhibition, partially abolished in presence of 2-mercaptoethanol
-
inactivation due to dissociation of FAD from the enzyme molecule and denaturation of the apoenzyme
-
0.1 mM HgCl2, complete inactivation
-
1 mM HgCl2, complete inhibition
-
complete inhibition at 10 mM
-
2.0 mM
-
complete inhibition at 1 mM (pH 7.0)
-
0.5 mM, complete inactivation
-
10 mM, 80% inhibition
-
1 mM
-
0.5 mM, isozyme E I: insensitive, isozyme E II: 54% inhibition; 72% reduced activity of isozyme E-II, no inhibition of isozyme E-I
-
1 mM, 90-95% inhibition
-
2.85 mM, 30% inhibition of pyridoxamine 5'-phosphate oxidation, 2% inhibition of pyridoxine oxidation
-
65% inactivation at 0.3 mM
-
75% inactivation at 0.1 mM
-
almost total inhibition at 0.1 mM
-
0.13 mM, complete inhibition
-
strong inhibition at 1 mM Hg2+
-
2 mM, 0% relative activity
-
strong inhibition
-
89% inhibition at 1 mM
-
1 mM, about 80% inhibition
-
strong inhibition at 1 mM
-
1 mM
-
96% inhibition at 0.1 mM
-
0.05 mM, complete inhibition. IC50: 0.00007 mM, noncompetitive inhibition; 0.05 mM, complete inhibition, noncompetitive
-
competitive inhibition
-
complete inhibition at 0.1 mg/ml
-
0.1 mM, complete inhibition
1 mM, 85% inhibition
-
0.5 mM, complete inhibition
-
about 70% inhibition
-
1 mM, 75% inhibition
-
IC50: 0.17 mM
-
about 70% inhibition
-
80% inhibition at 1 mM
-
1 mM, 2% residual activity
-
1 mM: not
-
98% inhibition at 1 mM
-
inhibitory
-
relative activity less than 5%
-
strong inhibition
-
1 mM shows strong inhibitory effect on recombinant rBfmBC activity (more than 80% inhibition)
-
complete inhibition at 1 mM
-
enzyme activity is drastically reduced (70%) by 1 mM
-
in the presence of NADPH, a ratio of 2 HgCl2 molecules to 1 TrxR dimer leads to a virtually inactive enzyme. On treatment with 0.005 mM selenite and NADPH, TrxR inactivated by HgCl2 displays almost full recovery of activity
-
potently inhibits (at concentrations of 5-50 nM) TrxR1 activity in both cell-free and intracellular assays
-
0.01 mM, 100% inhibition
-
complete inhibition at 1 mM
-
complete inhibition
-
0.1 mM, complete inhibition
-
5 mM, complete inhibition
-
0.1 mM, 96% inhibition
-
5 mM, complete inhibition
-
0.1 mM, strong inhibition
-
0.1 mM, no resiudal activity
-
0.01 M, strong
-
complete inhibition at 1 mM
-
relative activity 0% of control
-
at 1 mM, reversible by 10 mM DTT
-
100% inhibition at 0.05 mM
-
complete inhibition at 1 mM
-
strong
-
strong inhibition
-
strong inhibition at 1 mM
-
0.1 mM, 43% residual activity
-
0.1 mM; 50% inhibition
-
Hg(CHCOO)2, 0.1 mM, 70-90% inhibition
-
complete inhibition
-
0.1 mM, 65% inhibition
-
0.1 mM, complete inhibition
-
0.00001 mM, 50% inhibition, noncompetitive, irreversible, probably due to formation of a thiolate
-
complete inhibition at 0.1 mM
-
0.01 mM, complete inhibition
-
strong
-
strong inhibition
-
2-mercaptoethanol protects partly
-
isoenzyme a
-
11% remaining activity isoenzyme Nat-b; 36% remaining activity isoenzyme NAT-a
-
noncompetitive with respect to choline, IC50: 0.0004 mM, mixed type inhibition with respect to acetyl-CoA, IC50: 0.0025 mM, activity can be recovered using 2,3-dimercapto-propanol
-
complete inhibition
-
1 mM, 98% inhibition
-
1 mM, complete inhibition
-
5 mM, no residual activity
-
relative activity: 3%
-
19.8% residual activity after 1 h at 1 mM
-
5 mM HgCl2, 94% inhibition
-
1 mM 15% inhibition
-
1 mM, strong inhibition
-
hydrolase, not transferase reaction
-
strong
-
5 mM, complete inhibition
-
0.01 mM HgCl2, complete inhibition
-
95% inhibition at 2 mM
-
complete inactivation
-
0.05 mM, 21% inhibition of phosphorylase A, 73% inhibition of phosphorylase
-
0.1 mM, complete inhibition
-
1 mM, 77% inhibition of stromal phosphorylase
-
1 mM, complete inhibition
-
1 mM, strong inhibition
-
2 mM, complete inhibition
-
4 mM, more than 50% inhibition
-
irreversible inhibition, partial reactivation of the enzyme by GSH, but not by EDTA
-
irreversible inhibition, partial reactivation of the enzyme by GSH, but not by EDTA, about 90% inhibition at 0.0125 mM Hg2+, 80% at 0.01 mM
-
2% residual activity at 5 mM
-
20 ng/ml medium, 67.5% inhibition of the free enzyme, 54.3% inhibition of the immobilized enzyme
-
no inhibition by HgCl2, 5 mM
-
strong
-
1 mM, 100% inhibition
-
10 mM, up to 90% inhibition
-
1 mM
-
0.4 mM
-
80% inhibition at 1 mM
-
at 0.01 mM
-
complete inactivation
-
inhibition of 4-methylumbelliferone UDP-glucuronyltransferase
-
0.1 mM, residual activity 26%
-
strongly inhibits the sterol glucosyltransferase activity, IC50 (mM): 0.5
-
enzyme activity is completely inhibited by 0.1 mM Hg2+
-
1 mM, 5% of initial activity
-
95.9% residual activity at 5 mM
-
about 23% residual activity at 10 mM
-
complete inhibition at 1 mM
-
at 1 mM
-
1 mM, complete inactivation
-
complete inactivation at 1 mM
-
1 mM, partial inhibition
-
at least 10 mM
-
1 mM, 33% inhibition
-
10 mM, complete inhibition, reversed by addition of 20 mM 2-mercaptoethanol
-
complete inhibition at 10 mM
-
1 mM, 99% inhibition with quercetin as substrate
-
1 mM, no residual activity
-
10 mM, 56% inhibition
-
1 mM, 55% residual acitvity
-
0.1 mM, complete inhibition. The observed enzyme inhibition by Cu2+ and Hg2+ may not solely be attributed to their effects on the enzyme itself because these heavy metal ions are known to destroy substrate anthocyanins
-
complete inhibition at 5 mM
-
slight inhibition at 1 mM
-
1 mM, 35% inhibition
-
complete inhibition at 2 mM
-
10 mM, complete inhibition
-
1 mM, 50°C, 30 min, abolishes the phosphorolytic activity almost completely
-
1 mM, strong
-
97% inhibition at 1 mM
-
0.025 mM HgCl2, 53.8% inhibition
-
0.1 mM, 81% inhibition
-
10 mM, up to 90% inhibition
-
a concentration of 10 mM is deleterious for enzyme activity
-
HgCl2, 97% inhibition
-
moderate inhibitory effect
-
1 mM, 99.9% inhibition
-
complete inhibition at 5 mM
-
in presence of MnCl2
-
reversed by 2-mercaptoethanol
-
complete inhibition at 3 mM after 3 min at 0°C
-
3.3 mM
-
70% inhibition at 0.0009 mg/kg
-
70% inhibition at 0.1 mM
-
complete inhibition at 5 mM
-
noncompetitive
-
complete inhibition at 0.1 mM
-
complete inhibition at 1 mM
-
1 mM
-
reversed by dithiothreitol
-
0.0004 mM HgCl2, 80% inhibition
-
0.1 mm HgCl2, 76% inhibition
-
HgCl2, strong
-
inhibition by mercury derivates of porphobilinogen, i.e. PBG-Hg, and opsopyrroledicarboxylic acid, i.e. OPD-Hg, is enhanced by porphobilinogen; opsopyrroledicarboxylic acid enhances inhibition by HgCl2
-
strong
-
strongly inhibites both O-acetyl-L-serine sulfhydrylation and O-phospho-L-serine sulfhydrylation
-
weak
-
0.1 mM, 81% inhibition
-
93% inhibition
-
1 mM, 0% residual activity
-
0.1 mM, 89% inhibition
-
strong inhibition
-
strong inhibition, reducing agent reverses
-
0.1 mM, complete inhibition
-
strong
-
0.002 mM, 50% inhibition in the presence of 3 mM Mg2+
-
0.5 mM HgCl2, complete inhibition, activity is completely restored by 1 mM dithiothreitol
-
1 mM, complete inhibition
-
0.01 mM, 25% inhibition, 0.1 mM, almost complete inhibition
-
1 mM HgCl2, 18% inhibition
-
2 mM, at least 80% inhibition of transphosphorylation
-
55% inhibition at 1 mM
-
at PO2 of about 20 mM
-
0.1 mM, complete inhibition
-
0.083 mM, 76% inhibition
-
strong, not reaction of ADP + ADP
-
IC50: 0.017 mM
-
strong inhibition
-
0.1 mM, 90% inhibition
5 mM HgCl2, 78% inhibition
1 mM, 33% inhibition
-
10 mM, 62% inhibition
-
20 mM in presence of 10 mM Mg2+, more than 90% inhibition
-
partially reversed by dithiothreitol
-
strong inhibition at concentrations above 0.5 mM in presence of Mg2+
-
more than 70% inhibition at 0.1 mM
-
1 mM, almost complete inhibition
-
M-PST and P-PST, strong inhibition
-
recombinant enzyme form SULT1 ST5
-
10 mM, complete inhibition
-
50% inhibition at 0.001 mM
-
0.5 mM, complete inhibition; strong
-
1 mM, 50% loss of activity
-
1 mM, complete inhibition
-
90% inhibition
-
complete inhibition at 1 mM, 80% inhibition at 0.1 mM; HgCl2
-
inhibition at 1 and 10 mM
-
inhibits at 0.5-5 mM
-
strong inhibition
-
strong inhibition at 1 mM
-
almost complete inhibition at 5 mM
-
1 mM, no residual activity
-
1 mM, 11% residual activity
-
1 mM, 40% residual activity
-
1 mM, 50% residual activity
-
1 mM, complete loss of activity
-
15% inhibition
-
22.9% residual activity at 1 mM
-
50% inhibition at 0.01 mM
-
54% inhibition at 10 mM
-
strong for acid and less for neutral cholesterol esterases
-
20% residual activity at 10 mM
-
22% residual activity at 10 mM
-
25% residual activity at 10 mM
-
85% inhibition at 0.01 mM, 24 h preincubation
-
1 mM, 14% of initial activity
-
7.2% residual activity at 5 mM
-
complete inactivation at 5 mM Hg2+, after 30 min at 30°C
-
1 mM inhibits activity by 78%
-
53.02% residual activity at 20 mM
-
56% residual activity at 5 mM
-
57% inhibition at 1 mM
-
6% residual activity at 1 mM
-
66% inhibition at 1 mM
-
73% inhibition at 10 mM
-
competitive inhibition at 1 mM, 13.8% remaining activity
-
complete inhibition at 1 mM
-
complete inhibition of the free enzyme at 1 mM, the immobilized enzyme shows 93.7% residual activity at 1 mM
-
efficient inhibitor
-
inhibits both isozymes TAH I and TAH II
-
30% residual activity at 1 mM
-
2.1% residual activity at 1 mM
-
0.1 mM, complete inhibition
-
1 mM, 16% inhibition
-
1 mM, 89% inhibition
-
11% residual activity at 10 mM, with 4-nitrophenyl caproate as substrate, at 25°C
-
2 mM, pH 8.0
-
32.3% residual activity at 5 mM
-
43.75% residual activity at 1 mM
-
5 mM, 30 min, 70°C, pH 8.5, 55% inhibition
-
72% inhibition at 70 mM
-
75% inhibition at 1 mM
-
76% residual activity at 2 mM
-
77% residual activity at 1 mM
-
94% inhibition at 5 mM
-
activity is completely inhibited at 1 mM
-
almost complete inhibition at 1 mM
-
BTID-A, BTID-B
-
complete inhibition at 0.1 mM
-
complete inhibition at 1 mM
-
Hg2+ shows the highest reduction in enzyme activity by 83.3% at 1 mM
-
HgCl2
-
isozyme Lip-1 shows 20% relative activity in the presence of 5 mM Hg2+; isozyme Lip-2 shows 25% relative activity in the presence of 5 mM Hg2+
-
SSL and SML show 7% and 9% residual activity, respectively, in the presence of 10 mM Hg2+
-
strain KKA-5, strong inhibition
-
strong inhibition
-
strong inhibition with residual activity of 13.19% at 5 mM
-
5 mM
-
plasmalogen-specific PLA2
-
HgCl2
-
6% remaining activity after 5 min, 1 mM
-
5 mM, inhibits phospholipase B activity by 67%, no inhibition of lysophospholipase activity
-
61% residual activity at 1 mM
-
at pH 3.0
-
less than 2% residual activity at 10 mM
-
little effect
-
50% inhibition at 0.0035 mM
-
complete inhibition at 1 mM
-
little effect on the activity
-
strong inhibitor, 0.1 mM, acetyl esterase activity
-
strong inhibitor, 10 mM, 9% residual activity, EST1, p-nitrophenyl acetate as substrate
-
AChEA and AChEB are completely inhibited by 1 mM of Hg2+
complete inhibition at 1 mM
9% relative residual activity
-
1 mM inhibits completely; inhibits feruloyl esterase activity completely
-
1 mM, 10% of initial activity
-
5 mM, no resiudal activity
-
60% inhibition at 1.25 mM, about 70% inhibition at 2.5-10 mM
-
complete inhibition at 1 mM; complete inhibition at 1 mM
-
inhibitory at 5 mM
-
inhibits completely at 1 mM
-
inhibits isozyme Tfu 0882 and isozyme Tfu 0883 completely at 1 mM
-
1 mM, 82% inhibition
-
5 mM, 97% loss of activity
-
90% inhibition at 6 mM, completely reversible by 2-mercaptoethanol
-
complete inhibition at 5 mM
-
marked inhibition at 0.1 mM
-
0.005 mM, approx. 50% inhibition, 0.02 mM, approx. 70% inhibition
-
0.1 mM, 91% inhibition
-
0.1 mM, 96% inhibition
-
0.1 mM, complete inhibition
-
10 mM, 50-60% inhibition
-
complete inhibition at 1 mM
-
0.5 mM, strong inhibition
-
more than 75% enzyme activity inhibition
-
1 mM, 58% inhibition
-
no activity at 1 mM HgCl2
-
with RNA core as substrate
-
susceptible to inhibition by Hg2+
-
HgCl2
-
HgCl2, 0.5 mM, complete inhibition
-
HgCl2, most potent inhibitor
-
50% inhibition at 0.0006 mM, inhibition of both DNA glycosylase and apurinic nicking activities, binding capability not reduced
-
1 mM nearly complete inhibition of isoenzyme I, II and III
-
1 mM, 82% loss of activity
-
1 mM, complete inactivation
-
complete inhibition at 2 mM
-
0.1 mM, no residual activity
-
0.5 mM, 90% inhibition
1 mM, inhibition of hydrolysis of p-nitrophenyl phosphate, slight increase of ATP hydrolysis
10 mM, 56% inhibition
5 mM HgCl2, 82% inhibition
50.7% relative activity at 2.0 mM compared to the wild type enzyme
about 95% residual activity at 1 mM
HgCl2
mixed inhibition
more marked inhibition at pH 6.7 than at pH 5.4
strong inhibition of leaf and root nodule isozymes
strong inhibition of the isoenzymes AP-2, AP-3 and AP-4, less inhibitory to isoenzyme AP-1
uncompetitive
0.1-1 mM, strong
-
1 mM, 22% inhibition
-
48% inhibition at 10 mM, 87% inhibition at 20 mM. The enzyme may be a 3-phytase, EC 3.1.3.8, or a 6-phytase, EC 3.1.3.26. The product of the hydrolysis of myo-inositol hexakisphosphate i.e. myo-inositol 1,2,3,4,5-pentakisphosphate or myo-inositol 1,3,4,5,6-pentakisphosphate has not been identified
-
almost complete inhibition at 1 mM
-
inhibits activity
-
strong inhibition
-
complete inhibition at 0.5 mM
-
complete inhibition at 1 mM
-
competitive towards Mg2+
-
1 mM, 0.6% of initial activity
-
10% residual activity
-
31.17% residual activity at 5 mM
-
48% inhibition at 10 mM, 87% inhibition at 20 mM. The enzyme may be a 3-phytase, EC 3.1.3.8, or a 6-phytase, EC 3.1.3.26. The product of the hydrolysis of myo-inositol hexakisphosphate i.e. myo-inositol 1,2,3,4,5-pentakisphosphate or myo-inositol 1,3,4,5,6-pentakisphosphate has not been identified
-
5 mM
-
99.2% inhibitory effect at 5 mM
-
almost complete inhibition at 1 mM
-
complete inhibition; complete inhibition at 1-10 mM
-
strong inhibition
-
31.5% of maximal activity with 0.1 mM denaturated DNA, 48.2% with 0.5 mM polydeoxythymidylic acid as substrate, competitive inhibition
-
complete inactivation by 5 mM HgCl2
-
complete inhibition of 3'-AMP hydrolysis by 1 mM HgCl2
-
competitive
-
FS-44: 5'-PDase activity of bifunctional enzyme: cyclic-ribonucleotide phosphomutase-5'-phosphodiesterase
-
0.1 mM, 90% inhibition
-
inhibits PLC activity when added directly to the reaction mixture. Toxic effect stronger than that of Cu2+ both in vitro and in vivo, especially for the digestive gland
-
5 mM, complete inhibition
-
plasma membrane and microsomes
-
0.2 mM
-
0.2 mM, 35% inhibition of hydrolysis of di-p-nitrophenyl phosphate, 36% inhibition of 3'-AMP hydrolysis
-
study of in vivo inhibitory capacity, time course, recovery after 7 days
-
10 mM, complete inhibition
-
in the presence of Triton X-100
-
reduces activity by 30-40%
-
10 mM, more than 90% inhibition
-
94% inhibition at 1 mM
-
complete inactivation at 5 mM Hg2+, after 30 min at 30°C
-
noncompetitive inhibition of isoenzymes Q192 and R192
-
plasma enzyme more resistant than liver enzyme
-
strong
-
strong inhibition at 1 mM
-
0.1 M, 98% inhibition
0.5 mM HgCl2, 60% inhibition
1 mM HgCl2, 88% inhibition
1 mM HgCl2, 89.5% inhibition
1 mM, 15% residual activity
1 mM, 25% inhibition
1 mM, 37°C, 30 min, pH 6.5, 44% relative activity
1 mM, 66% inhibition
1 mM, 82% loss of activity
1 mM, complete inactivation
1 mM, complete inhibition
1 mM, complete inhibition of wild-type enzyme and mutant enzyme L134R/S320A
1 mM, pH 8.0, 24 h at 4°C, 35% and 31% residual activity for Amy I and Amy II, respectively
10 mM, 55% inhibition
10 mM, 88% loss of activity
10 mM, 98% inhibition
10 mM, strong inhibition of enzyme form Amyl I, Amyl II and Amyl III
2 mM, almost complete inhibition
2 mM, complete inhibition
5 mM HgCl2, 98% inhibition
5 mM HgCl2, 99% inhibition
5 mM, 28% inhibition
5 mM, 64% loss of activity
5 mM, 85% inhibition
62% inhibition at 5 mM
73% inhibition of wild-type and mutant enzymes at 5 mM
activity severely inhibited, indicates the role of sulfydryl group in catalysis
addition to growth medium in logarithmic phase, 0.025 mM, no enzyme expression. Addition to enzyme assay, 69% inhibition at 0.5 mM
complete inhibition
complete inhibition at 1 mM
complete inhibition at 2 mM
complete inhibition at 4 mM
complete inhibition at 5 and 10 mM
complete inhibition at 5 mM
complete inhibition at 5 mM, 94% inhibition at 1 mM
complete inhibition at 5 mM, at 80°C and pH 5.0
complete inhibition of isozymes AI-1 and AI-2, and AII at 5 mM
partially reversed by Cys
strong inhibition
99% inhibition by 2 mM HgCl2
-
complete inhibition by 1 mM HgCl2
-
complete inhibition by 2 mM in 20 mM borate buffer, pH 7.5 with p-nitrophenyl-alpha-D-glucopyranoside as substrate
-
1 mM, complete inhibition
-
1 mM, complete inhibition
-
potent inhibitor, inhibition reversed by adding an excess of dithiothreitol
-
1 mM, no resiudal activity
-
10 mM, 17% residual activity
-
complete inhibition of the free enzyme and the immobilized enzyme
-
strong inhibitor
-
strong
1.33 mM, 1.2% relative activity
-
1 mM
-
10 mM, 83% loss of activity
-
17% residual activity at 10 mM
-
weak, 1 mM: 15% inhibition, 10 mM: 75% inhibition
-
strong, with p-nitrophenyl-beta-D-glucopyranoside as substrate
-
85% inhibition at 1 mM
-
complete inhibition at 2 mM
-
complete inhibition at 5 mM
-
completely inhibits enzyme activity
-
1 mM, no residual activity
-
1 mM completely inhibits, with colloidal chitosan as substrate
-
1 mM, 44% inhibition
-
1 mM, 68% inhibition
-
1 mM, 80% loss of activity
-
1 mM, about 75% loss of activity
-
81% inhibition of chitosanase I and 80% inhibition of chitosanase II
-
98% inhibition at 1 mM
-
complete deactivation
-
complete inhibition at 1 mM
-
HgCl2
-
inhibition of chitosanase A and B
-
inhibits 37% at 1 mM
-
isoform B shows 77% residual activity at 0.25 mM
-
strong inhibition
-
about 2.7% residual activity at 10 mM
-
complete inhibition at 1 mM
-
enzyme activity decreases to 17.5% in the presence of 5 mM HgCl2
-
98% inhibition at 1 mM
-
1 mM, complete inhibition
-
1 mM, no residual activity
-
1 mM, strong inhibition
-
2 mM, 58% inhibition
-
25% inhibition at 0.1 mM, complete inhibition at 1 mM
-
0.1 mM, 4% residual activity
-
1 mM, 34% of initial activity
-
1 mM, 58% of initial activity, isoform Chi-56, 54% of initial activity, isoform Chi-64
-
1 mM, complete inhibition
-
1 mM, complete inhibition of hydrolysis of 4-methylumbelliferyl-N,N'-diacetylchitobiose and 4-methylumbelliferyl-N,N',N''-triacetylchitotriose
-
1 mM, more than 90% inhibition, chitinase 1
-
10 mM, complete loss of activity
-
10% residual activity at 5 mM
-
100% inhibition at a concentration of 1 mM
-
35% residual activity at 1 mM
-
42% inhibition at 2.5 mM
-
5 mM, 60% residual activity
-
81% inhibition at 1 mM
-
complete inhibition
-
complete inhibition at 2 mM
-
complete inhibition at 5 mM
-
strong inhibition
-
0.4 and 4 mM strongly inhibit
-
1 mM, almost complete inhibition
-
0.5 mM, complete inhibition
-
1 mM, 87% inhibition
-
2 mM inhibits 100% of enzyme activity
-
46.3% residual activity with 1mM
-
64.2% residual activity at 1 mM
-
90.5% of activity reduction
-
96% inhibition at 0.5 mM
-
complete inhibition
-
complete inhibition at 1 mM
-
complete inhibition at 10 mM
-
stronger inhibitor for PG1 than for PG2
-
0.01 mM, almost complete inhibition
-
1 mM, complete inhibition
-
91% inhibition at 1 mM
-
strong
-
1 mM, 80% inhibition
-
76% residual activity at 1 mM
-
complete inhibition at 1 mM
-
inhibits activity at 1 mM, 6% relative activity compared with activity without any addition of effector
-
1 mM complete loss of activity
-
1 mM, 77% inhibition
-
high concentrations, 50% inhibition at 5.2 mM
-
1 mM, 88% loss of activity
-
complete inhibition at 1 mM
-
10 mM, significant inhibition
-
10 mM, complete inhibition
-
94% inhibition at 1 mM
-
complete inhibition at 1-5 mM
-
1 mM, no residual activtiy
-
0.001-0.1 mM HgCl2
-
0.5 mM
-
1 mM, almost complete inhibition of mutant enzyme M185L/S295A/I297V/S350P/S351P/Q352D/A376S
-
1 mM, almost complete inhibition of recombinant enzyme
-
5 mM, 37°C, 30 min, about 80% inhibition
-
0.1 M, complete inhibition
-
1 mM, complete inhibition
-
98% inhibition at 0.1 mM, due to existence of essential sulfhydryl groups in the enzyme
-
almost complete inhibition at 5 mM
-
at least 80% inhibition at 5 mM
-
complete inhibition at 1 mM
-
10 mM, complete loss of activity
-
5 mM, complete inhibition
-
5 mM, 25% loss of activity
-
no activity is detected after 1 h of incubation at 1mM Hg2+
-
0.06 mM, 97% inhibition
-
1 mM, 38% inhibition, 10 mM, 77% inhibition
-
1 mM, 55% loss of activity of native enzyme, 58% loss of activity of recombinant enzyme, beta-glucosidase activity
-
1 mM, complete inhibition
-
1 mM, complete inhibition, 73% reversion by addition of 10 mM dithiothreitol
-
10 mM, 32% inhibition
-
14% inhibition at 1 mM
-
2 mM, 54% residual activity
-
2 mM, complete inhibition
-
2 mM, significant inhibition, both isoforms beta-glu 2 and beta-glu 1
-
33% inhibition at 1 mM, 48% at 5 mM
-
40.9% residual activity of cellobiase produced in the presence of 2-deoxy-D-glucose at 2.0 mM
-
50% inhibition at 2 mM
-
70% inhibition at 2 mM
-
89% inhibition at 0.1 mM
-
90% inhibition at 1 mM
-
93% inhibition at 1 mM
-
95% inhibition at 1 mM
-
95.5% inhibition at 4 mM
-
99% inhibition at 1 mM
-
complete inactivation at 0.1 mM
-
complete inhibition
-
complete inhibition at 1 mM
-
complete inhibition at 2 mM
-
complete inhibition at 5 mM
-
remarkable inhibition at 1 mM
-
significant inhibition
-
slight inhibition at 1 mM
-
slight inhibition at 1 mM only for beta-glucosidase I
-
strong inactivation at 0.5 mM, reversal by addition of 10 mM beta-mercaptoethanol
-
strong inhibition
-
strong inhibition at 1 mM
-
strong inhibition at 10 mM
-
strong inhibition at 2 mM
-
strong inhibition at 5 mM
-
strong inhibitor
-
the mycelial extract shows 26.8% residual activity at 20 mM, the purified enzyme shows 1.2% residual activity at 20 mM
-
0.1 M, 80% loss of activity
-
1 mM, 91% inhibition
-
1 mM, 98% inhibition
-
1 mM, more than 95% inhibition
-
1 mM, strong inhibition
-
8% of initial activity
-
alpha-Gal II, 93% decrease of activity at 1 mM; alpha-Gal III, 87% decrease of activity at 1 mM
-
complete inhibition at 1.25 mM
-
complete inhibition at 10 mM
-
completely inhibits activity
-
inactivation
-
inhibits enzymatic activity
-
isoform Ag-I shows 5% residual activity and isoform Ag-II is completely inhibited by 5 mM Hg2+
-
no activity at 1 mM
-
potent inhibitor
-
strong
-
strong inhibitor
-
strongly inhibits AgalB activity
-
0.001 M, complete inhibition
-
0.005 mM, 64.5% inhibition
-
0.01 4 mM CuSO4, 36% inhibition
-
0.1 mM HgCl2, complete inhibition
-
0.1 mM, complete inactivation
-
0.2 mM, complete inhibition
-
1 mM, 95% inhibition
-
1 mM, 95% inhibition of beta-galactosidase I, 95% inhibition of beta-galactosidase II, 91% inhibition of beta-galactosidase III
-
1 mM, almost complete inhibition
-
1 mM, complete inhibition
-
1-2.5 mM
-
10 mM HgCl2, 12% inhibition
-
10 mM, complete inactivation
-
10 mM, no residual activity
-
2.0 mM, 66% inhibition
-
complete inhibition at 1 mM of recombinant isozyme OsGal1
-
complete inhibition at 5 mM
-
45% inhibition at 10 mM
-
complete inhibition at 1 mM
-
complete inhibition at 10 mM
-
slight inhibition at 1 mM for isoforms I,II
-
strong inhibitor
-
0.05 mM, 50% inhibition
-
1 mM, 98% loss of activity
-
0.002 mM, 55% inhibition of invertase I, complete inhibition of invertase II
-
0.002 mM, complete inhibition; HgCl2
-
1 mM
-
1 mM, 67% inhibition
-
1 mM, 93% inhibition of isozyme IT I, 95% inhibition of isozyme IT II
-
1 mM, complete inhibition
-
1 mM, complete inhibition of beta-fructofuranosidase activity, 65% inhibition of invertase activity
-
1.7 mM HgCl2, complete inhibition
-
10 mM HgCl2
-
10 mM, no residual activity
-
2 mM, no residual activity
-
44% inhibition at 0.01 mM, 96% inhibition at 1 mM
-
5 mM, complete loss of activity
-
65% inhibition at 0.001 mM
-
inhibits native invertase INVA, invertase INVA expressed in Pichia pastoris under the control of the strong AOX1 promoter, native invertase INVB and native invertase INVB expressed in Pichia pastoris under the control of the strong AOX1 promoter
-
invertase I is more than 2fold more resistant than invertase IIA and IIB
-
no inhibition of neutral and alkaline invertase
-
strong inhibition
-
0.1 mM, complete inhibition
-
0.11 mM HgCl2. Cl- protects from inactivation by HgCl2
-
1 mM HgCl2, complete inhibition
-
1 mM, 58% inhibition
-
1 mM, complete inhibition
-
1 mM, no residual activity, both isoforms
-
10 mM HgCl2, 30% loss of activity
-
2 mM HgCl2, 61.7% inhibition
-
HgCl2
-
the glycoprotein enzyme forms are more susceptible than the nonglycoprotein forms
-
1 mM, 48% inhibition, glucoamylase M2
-
1 mM, 49% inhibition, glucoamylase M1
-
1 mM, 64-70% inhibition
-
1 mM, 70% inhibition
-
10 mM, 10% residual activity
-
10 mM, strong inhibition
-
32% inhibition at 1 mM, 69% at 10 mM
-
34% inhibition of isozyme GA-II, 49% inhibition of isozyme GA-I at 1 mM
-
46% inhibition at 0.002 mM
-
5 mM, 53% inhibition
-
5 mM, 7% residual activity; 5 mM, no residual activity
-
5 mM, 70% inhibition
-
5 mM, about 30% residual activity
-
52% inhibition at 5 mM
-
89% inhibition at 1 mM
-
complete inhibition
-
complete inhibition at 1 mM
-
potent inhibitor for glucoamylase I and II
-
strong inhibition
-
1 mM, 37°C, 10 min, 23% inhibition
-
reversed by EDTA
-
1 mM, 60% loss of activity. 10 mM, 74% loss of activity
-
1 mM, complete inhibition
-
1 mM, strong
-
1 mM, strong inhibition
-
1 mM, 3% of initial activity
-
43% inhibition at 5 mM
-
complete inhibition at 0.8 mM
-
moderate inhibition at 20 mM
-
0.1 mM, complete loss of activity
-
1 mM, 40% inhibition
-
1 mM, 91% inhibition
-
1 mM, complete inhibition
-
1 mM, complete loss of activity
-
10 mM, 8% residual activity
-
5 mM, 49% residual activity of native enzyme, 64% of immobilized enzyme
-
50% inhibition
-
86.23% residual activity at 0.1 mM
-
91% inhibition at 1 mM
-
about 10% residual activity at 5 mM in acetate buffer
-
competitive inhibition
-
complete inhibition
-
complete inhibition at 0.1 mM
-
complete inhibition at 1 mM
-
complete inhibition at 1 mM, 93% inhibition at 0.1 mM
-
complete inhibition at 2 mM
-
complete inhibition at 50 mM
-
complete inhibition of xylan-inducible enzyme and xylose-inducible enzyme, at 1 mM
-
strong inhibition
-
strong inhibition at 0.1 mM
-
strong inhibition at 1 mM
-
strong inhibition for all four isoenzymes
-
89% inhibition at 1 mM
-
complete inhibition at 25 mM
-
effective inhibitor at 10 mM
-
inhibition at 1 mM
-
strong inhibition
-
strong inhibition at 0.001 mM
-
0.1 mM
-
1-5 mM, strong
-
36% inhibition at 1 mM
-
39% inhibition at 1 mM
-
5 mM, 93% inhibition
-
5 mM, no residual activtiy
-
52% inhibition for laminarin, 62% inhibition for pustulan
-
complete inhibition at 1 mM
-
inhibition at 0.2 mM
-
inhibition at 0.4 mM
-
inhibition at 1 mM
-
inhibition on both laminarin hydrolysis and disruption of living yeast cells
-
marked inhibition at 1 mM
-
strong inhibition at 2 mM
-
1 mM HgCl2, complete inhibition
1 mM, 12% residual activity
1 mM, 2% residual activity
1 mM, 30% residual activity
1 mM, 40% residual activity
1 mM, 67% inhibition
1 mM, complete inactivation
1 mM, complete inhibition
1 mM, complete loss of activity
1 mM, no residual activity
1 mM, represses the enzyme activity up to 22%
1 mM, strong inhibition
1.0 mM, significant inhibition
10 mM, complete inhibition
2 mM, 20% inhibition
2 mM, cellulase I
21% inhibition at 1 mM
5 mM, 10% residual activity
5 mM, 21.9% residual activity, 50%, 48 h, crude enzyme preparation
5 mM, 45% residual activity
5 mM, 46% residual activity
5 mM, 58% inhibition
5 mM, 95% inhibition
5 mM, no residual activity
73.5% inhibition at 5 mM
78% inhibition
endoglucanase E1 and E2; HgCl2
Hg(acetate)2, restored by Cys or Cl-
inhibition of cellulose hydrolysis and carboxymethylcellulose hydrolysis
strong inhibition
1 mM, 99% loss of activity
-
10 mM
-
10 mM, 99% loss of activity
-
0.1 M, 70% loss of activity
-
1 mM, 99% loss of activity
-
1 mM, complete inactivation
-
5 mM, at least 60% inhibition
-
5 mM, complete inhibition, pH 6.5, 70°C
-
complete inactivation
-
complete inhibition at 5 mM
-
10 mM, 12% residual activity
-
isoenzyme II
-
slight inhibition of isozyme alpha-GalNAcase I, strong inhibition of isozyme alpha-GalNAcase II
-
noncompetitive
-
1 mM, complete inactivation
-
92% inhibition at 0.1 mM
-
complete inactivation at 0.1 mM, complete reversal by addition of 1.1 mM DTT
-
complete inhibition at 1 mM
-
effective inhibition at 5 mM
-
effective non-competitive inhibition at 2 mM
-
marked inhibition at 0.1 mM
-
marked inhibition at 20 mM
-
potent inhibitor at 1 mM
-
0.01 mM, 19% inhibition, 2 mM cause 97% inhibition
0.05 and 0.1 mM cause 45 and 70% inhibition
0.05 mM results in significant inhibition
0.25 mM, significant inhibition
1 mM reduces activity by 89%
1 mM, 97% inhibition of isoenzyme I, 95% inhibition of isoenzyme II
1 mM, about 50% inhibition
10 mM, 33% loss of activity
37% inhibition with 0.01 mM, complete inhibition with 2 mM
5% residual activity at 1 mM
added with substrate: with 0.0025 mM 45% of activity remains, enzyme incubated before addition of substrate: with 0.0025 mM 25% of activity remains
all 4 forms
all 4 isozymes, at 1 mM
complete inactivation with 0.1 mM
completely inactivates all 3 enzyme forms in colonic mucosa
concentration of 0.1 mM results in total loss of activity
concentration of 1 mM causes complete inhibition
concentration of 10 mM causes 39% inhibition
concentration of 10 mM results in 97% inhibition
concentration of 2 mM causes 98.9% inhibition
concentration of 7 mM results in total loss of activity
Ex 1, Ex 2 and alimentary canal enzyme
isoenzyme I; isoenzyme II
low molecular weight form EII, at 0.25 mM
minor isozyme: 5% of activity remains with 0.01 mM, major isozyme: 53% of activity remains with 0.01 mM
slight inhibition at 10 mM
strong inhibition at 5 mM
with 0.03 mM 7.1% of activity remains
with 0.75 M 6% of activity remains
with 1 mM 13% of activity remains
with 1 mM 50% of activity remains, with 5 mM 10% of activity remains
with 1 mM 84% of N-acetylgalactosaminidase and 90% of N-acetylglucosaminidase activity remains
with 2 mM hydrolysis of p-nitrophenyl-beta-2-acetamido-2-deoxy-D-glucopyranoside is reduced to 24%, hydrolysis of p-nitrophenyl-beta-2-acetamido-2-deoxy-D-galactopyranoside to 20%
5 mM, strong inhibition
-
82.5% inhibition at 5 mM
-
reduces activity to 24%
-
relative activity 1.6%
-
1 mM Hg(Ch3COO)2
-
1 mM HgCl2 inhibits the activity by 98%
-
1 mM, complete inhibition
-
1 mM, no residual activtiy
-
2% residual activity at 5 mM
-
59% residual activity at 1 mM
-
80% inhibition at 20 mM
-
90% inhibition of AFQ1, 74% inhibition of AFS, at 1 mM
-
alpha-L-arafase I
-
complete inhibition at 1 mM
-
strong inhibition
-
5 mM complete inactivation
-
1 mM, 86% of activity
-
5 mM, 40% residual activity
-
5 mM, 40% residual actvity
-
over 97% inhibition at 5 mM
-
strong
-
irreversible inhibition
-
1 mM, 39% inhibition
-
1 mM, slight inhibition
-
2 mM, complete loss of activity
-
33% loss of activity by 0.5 mM
-
60% loss of activity by 0.1 mM
-
87% loss of activity by 0.1 mM
-
96% inhibition of beta-1,3-glucanase IV activity after incubation with 1 mM at 5°C, pH 6.0, for 3 h, no inhibition in presence of beta-mercaptoethanol
-
99% inhibition with 10 mM
-
complete inhibition by 2 mM HgSO4
-
1 mM HgCl2, amylase A, 99% inhibition, amylase B, 97% inhibition
-
1 mM HgCl2, complete inhibition
-
F1 and F2 form, complete inhibition
-
0.1 mM, complete inhibition
-
1 mM reduces activity 15-28%
-
10 mM, complete inhibition
-
31.41% residual activity at 10 mM
-
about 50% residual activity at 2 mM
-
at 1 mM 17% inhibition, at 5 mM 48% inhibition
-
complete inhibition at 1 mM
-
complete inhibition at 2 mM
-
complete inhibition at 5 mM
-
inhibitory at 10 mM
-
isoform exoPG1 shows 50% inhibition at 1 mM, isoform exoPG2 shows 97% inhibition at 1 mM
-
52% inhibition
-
complete inhibition at 0.5 mM
-
0.02 mM
-
1 mM, 25% residual activity
-
1 mM, 33% inactivation
-
1 mM, complete inactivation
-
more than 90% inhibition
-
1 mM, 36% residual activity
-
14.7% residual activity at 1 mM; strong inhibition
-
complete inhibition
-
complete inhibition at 1 mM
-
complete inhibition at 10 mM
-
complete inhibition at 5 mM
-
complete inhibition of both isozymes at 2.5 mM
-
completely inhibits the enzyme activity at 4 mM
-
strong inhibition
-
5 min at 50ºC, 10 mM, 100.0% inhibition; 5 min at 50ºC, 1 mM, 100.0% inhibition
-
competitive inhibition, 4.3% residual activity at 10 mM
-
slight inhibition
-
1 mM, 1% residual activity
1 mM, 2% residual activity
1 mM, 4% residual activity
1 mM, 8% residual activity
1 mM, more than 80% inhibition
4% residual activity at 1 mM
5 mM, 16.4% residual activity
complete inhibition
complete inhibition at 1 mM
strong inhibition
0.07 mM, xylanase I and II
-
0.1 mM
-
0.1 mM, 30% inhibition
-
1 mM
-
1 mM completely inhibits
-
1 mM HgCl2, complete inhibition, xylanase A
-
1 mM, 1% residual activiy
-
1 mM, 10% residual activity
-
1 mM, 3% residual activity
-
1 mM, 32% residual activity
-
1 mM, 4.2% residual activity
-
1 mM, 50% inhibition
-
1 mM, 55% resiudal activity
-
1 mM, 60% residual activity
-
1 mM, complete inhibition
-
1 mM, complete inhibition of xylanase A and B
-
1 mM, complete loss of activity
-
1 mM, no residual activity
-
10 mM
-
10 mM, 65% residual activity
-
10 mM, 70% inhibition
-
10 mM, 85% inhibition
-
10 mM, significant inhibition
-
2 mM, 20% residual activity for isoforms xynA, xynC, 67% residual activity for isoform xynB
-
2 mM, 23% residual activity; 2 mM, 73% residual activity; 2 mM, no residual activity
-
2 mM, complete inhibition
-
2 mM, complete loss of activity; 2 mM HgCl2, complete inactivation
-
27% residual activity at 1 mM
-
31% inhibition at 1 mM
-
5 mM, 10% residual activtiy
-
5 mM, 34% residual activity
-
5 mM, 8% of initial activity
-
5 mM, enzyme component I and II of strain W1 and W2, completely inhibited
-
5 mM, no residual activity
-
6 mM, complete inhibition
-
6 mM, complete inhibition. Addition of 40 mM EDTA does not recover any lost activity
-
7.5 mM, strong inhibition
-
75% residual activity at 5 mM
-
96% inhibition at 10 mM
-
almost complete inhibition at 5 mM
-
almost completely inhibits
-
both isoform xyl I, xyl II, complete inhibition
-
complete inhibition
-
complete inhibition at 1 mM
-
complete inhibition at 2 mM
-
complete inhibition at 5 mM
-
complete inhibition of XYN10G at 5 mM
-
completely inhibits
-
HgCl2
-
HgCl2, xylanase A, B and C
-
inhibition of isozymes Ic and IIb
-
inhibits the native enzyme
-
no activity at 2 mM
-
strong inhibition
-
strong inhibition of xylanase I and xylanase II
-
strong inhibitory effect
-
strong, both xylanase I and xylanase II
-
strong, no reactivation by EDTA
-
1 mM, 100% of inhibition
-
1.0 mM, pH 5.0, at 30ºC, 100% inhibition
-
30 min at 30ºC, 10 mM, 85% inhibition; 30 min at 30ºC, 1 mM, 26% inhibition; 30 min at 30ºC, 5 mM, 57% inhibition
-
at 55ºC, pH 4.5, 5 mM, 91% inhibition
-
decreased activity at concentrations of 1.0 mM
-
less than 50% of residual enzymatic activity at 20 mM
-
potent inhibitor below 1mM
-
1 mM
-
1 mM, complete inhibition
-
1 mM, no residual activity
-
5 mM, complete inhibition of agarase AG-b
-
complete inhibition at 1 mM
-
completely inhibits
-
0.3% residual activity at 50 mM
-
15.35% residual activity at 1 mM
-
3% residual activity at 10 mM
-
complete inhibition at 1 mM
-
5 mM, complete inhibition
-
1 mM, extremely inhibitory
-
4% residual activity at 1 mM, complete inhibition at 10 mM
-
60% inhibition at 1 mM
-
complete inhibition at 1 mM
-
complete inactivation at 25 mM
-
1 mM HgCl2, 60% loss of activity
-
1 mM HgCl2, 85% loss of activity
-
1 mM HgCl2, about 50% inhibition
-
1 mM, significant inactivation
-
2 mM, complete inhibition
-
2.5 mM, complete inhibition
-
5 mM, 20% inhibition
-
extracellular enzyme, completely
-
G-6, very strong inhibition
-
immobilized enzyme, 61% inactivation; native enzyme, completely
-
native enzyme, completely
-
1 mM, 8% residual activity
-
complete inhibition at 1 mM
-
completely
-
F-11
-
IFO 3022, completely
-
IFO 3134, completely
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5 mM, complete inhibition of agarase AG-b
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about 80% residual activity at 1 mM
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complete inhibition
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complete inhibition at 1 mM
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1 mM, complete inhibition of 2-nitrophenyl beta-D-galactopyranoside hydrolysis and 4-nitrophenyl beta-D-glucopyranoside hydrolysis
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1 mM,61% inhibition
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10 mM HgCl2, 70% inhibition
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complete inhibition at 2 mM; inhibition of NADase and adenosine diphosphate cyclase
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70% inhibition at 1 mM
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complete inhibition at 1 mM
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inhibition of phosphatase activity and epoxide hydrolase activity
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5 mM, 36% residual activity
-
70% inhibition at 1 mM
-
90% inhibition at 1 mM
-
over 90% inhibition at 1 mM
-
1 mM, complete inhibition
-
HgCl2
-
1 mM, complete inhibition
-
71% inhibition at 1 mM
-
complete inhibition at 1 mM
-
99% inhibition at 1 mM, recombinant enzyme
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strongly inhibitory at 0.1 mM
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1 mM, 0.8% residual activity
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almost inactivates the enzyme
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0.1 mM HgCl2, complete inhibition
-
complete inhibition at 0.1 mM
-
complete inhibition at 1 mM
-
complete inhibition at 1 mM
-
HgCl2
-
98% inhibition at 1 mM
-
strong, reversible by dialysis against 2 mM DTT
-
0.001 mM, 3% residual activity
-
1 mM HgCl2, 78% inhibition
-
98% inhibition at 1 mM
-
complete inhibition at 1 mM, preincubation at room temperature for 15 min
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HgCl2
-
significant inhibition
-
11.1% residual activity at 0.1 mM
-
0.1-2.5 mM
1 mM, 70% inhibition
HgCl2
1 mM, complete inhibition, IC50: 0.67 mM
-
HgCl2
-
1 mM, 90% inhibition
-
1 mM, 97% inhibition
-
inhibits activity
-
100% inhibition at 1 mM
-