Ligand AMP

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Basic Ligand Information

Molecular Structure
Picture of AMP (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H14N5O7P
AMP
UDMBCSSLTHHNCD-KQYNXXCUSA-N
Synonyms:
3-beta-ribofuranosyladenine 5'-monophosphate, 5'-adenosine monophosphate, 5'-adenylic acid, 5'-AMP, 5'AMP, 5-AMP, 6-aminopurine nucleotides, adenine 9-beta-D-riboside 5'-phosphate, adenine nucleotide, adenine nucleotides, adenosine-5'-monophopsphate, adenosine-5'-monophosphate, adenosine-5'-phosphate, adenosine-5-phosphate, adenosine 5'-monophosphate, adenosine 5'-phosphate, adenosine 5-phosphate, adenosine monophosphate, adenosine nucleotides, adenosine phosphates, adenylate, adenylic acid, adenylic acids, AMP2-
Pathway Source
Pathways
MetaCyc
(+)-camphor degradation, (-)-camphor degradation, (-)-microperfuranone biosynthesis, (2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis, (5R)-carbapenem carboxylate biosynthesis more


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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (56 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
AMP + phosphate = adenine + alpha-D-ribose 1,5-bisphosphate
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dimethylallyl diphosphate + AMP = diphosphate + N6-(dimethylallyl)adenosine phosphate
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AMP + thymidine = adenosine + dTMP
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AMP + trans-farnesyl triphosphate = ?
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AMP + phosphoenolpyruvate + diphosphate = ATP + pyruvate + phosphate
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AMP + H2O = adenosine + phosphate
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AMP + H2O = IMP + NH3
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AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine = ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine
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In Vivo Product in Enzyme-catalyzed Reactions (773 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
luciferin + O2 + ATP = oxyluciferin + AMP + CO2 + light
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luciferin + O2 + ATP = oxyluciferin + AMP + CO2 + light
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L-tyrosine + NADPH + H+ + ATP = L-tyrosinal + NADP+ + AMP + diphosphate
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L-2-aminoadipate + NADPH + H+ + ATP = (S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
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ADP + thymidine = AMP + dTMP
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ATP + adenosine = ADP + AMP
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ADP + L-serine = AMP + O-phospho-L-serine
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ATP + (R)-4-phosphopantoate + beta-alanine = AMP + diphosphate + (R)-4'-phosphopantothenate
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ATP + L-glutamine + H2O = AMP + phosphate + N5-phospho-L-glutamine
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ADP + [phosphate]n = AMP + [phosphate]n+1
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Urm1p-terminal-Gly-AMP + Uba4-SSH = Urm1p-terminal-Gly-COSH + human MOCS2A-SH + AMP
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ATP + pyruvate + phosphate = AMP + phosphoenolpyruvate + diphosphate
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ATP + pyruvate + H2O = AMP + phosphoenolpyruvate + phosphate
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ATP + rifampicin + H2O = AMP + 21-phosphorifampicin + phosphate
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[molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine = AMP + [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + cysteine desulfurase
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a [protein]-S-sulfanyl-L-cysteine + 5-taurinomethyluridine34 in tRNA + ATP + reduced acceptor = a [protein]-L-cysteine + 5-taurinomethyl-2-thiouridine34 in tRNA + AMP + diphosphate + acceptor
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Urm1p-terminal-Gly-AMP + Uba4-SSH = Urm1p-terminal-Gly-COSH + Uba4-SH + AMP
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sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) = sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP
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adenosine 5'-phosphosulfate + dithiothreitol = AMP + ?
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adenosine-5'-diphospho-5'-[DNA] + H2O = AMP + phospho-5'-[DNA]
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3',5'-cAMP + H2O = 5'-AMP
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5'-O-phosphonoadenylyl-(3'->5')-adenosine + H2O = 2 AMP
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ADP + H2O = AMP + phosphate
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5'-acylphosphoadenosine + H2O = AMP + carboxylate
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ADP-sugar + H2O = AMP + sugar phosphate
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ATP + H2O = AMP + diphosphate
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adenosine 5'-phosphosulfate + H2O = AMP + SO42-
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ATP + H2O = AMP + diphosphate
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FAD = AMP + riboflavin cyclic-4',5'-phosphate
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ATP + L-phenylalanine + H2O = AMP + diphosphate + D-phenylalanine
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ATP + UDP-MurNAc-L-Ala-L-Glu = AMP + diphosphate + UDP-MurNAc-L-Ala-D-Glu
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ADP + H2O + a folded polypeptide = AMP + phosphate + an unfolded polypeptide
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ATP + L-cysteine + tRNACys = AMP + diphosphate + L-cysteinyl-tRNACys
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ATP + L-asparagine + tRNAAsn = AMP + diphosphate + L-asparaginyl-tRNAAsn
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ATP + L-isoleucine + tRNAIle = AMP + diphosphate + L-isoleucyl-tRNAIle
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ATP + L-valine + tRNAVal = AMP + diphosphate + L-valyl-tRNAVal
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ATP + L-glutamate + tRNAAsp = AMP + diphosphate + L-glutamyl-tRNAAsp
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tobramycin + carbamoyl phosphate + ATP + H2O = nebramycin 5' + AMP + diphosphate + phosphate
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ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA
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ATP + acetoacetate + CoA = AMP + diphosphate + acetoacetyl-CoA
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ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA
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4-Chlorobenzoate + CoA + ATP = 4-Chlorobenzoyl-CoA + AMP + diphosphate
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3-hydroxypropanoate + ATP + coenzyme A = 3-hydroxypropanoyl-CoA + AMP + diphosphate
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ATP + 3-hydroxybenzoate + CoA = AMP + diphosphate + 3-hydroxybenzoyl-CoA
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[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetate + ATP + CoA = AMP + diphosphate + [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA
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ATP + 4-hydroxybutanoate + CoA = AMP + diphosphate + 4-hydroxybutanoyl-CoA
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ATP + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + CoA = AMP + diphosphate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA
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ATP + 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + CoA = AMP + diphosphate + 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA
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ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine
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ATP + L-carnitine + CoA = AMP + diphosphate + L-carnitinyl-CoA
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ATP + a long-chain fatty acid + holo-[mycocerosate synthase] = AMP + diphosphate + a long-chain acyl-[mycocerosate synthase]
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ATP + L-firefly luciferin + CoA = AMP + diphosphate + L-firefly luciferyl-CoA
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ATP + D-alanine + poly(ribitol phosphate) = AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
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ATP + 3,4-dihydroxybenzoate + holo-[aryl-carrier protein] = AMP + diphosphate + 3,4-dihydroxybenzoyl-[aryl-carrier protein]
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ATP + L-arginine + holo-[L-arginyl-carrier protein] = AMP + diphosphate + L-arginyl-[L-arginyl-carrier protein]
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ATP + oxalate + CoA = AMP + diphosphate + oxalyl-CoA
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3-phenylpropanoate + CoA + ATP = 3-phenylpropionyl-CoA + AMP + diphosphate
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ATP + L-alanine + [acyl-carrier protein Atu2571] = AMP + diphosphate + L-alanyl-[acyl-carrier protein Atu2571]
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ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine
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1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP = 1-O-[2-(L-cysteinamido)-2-deoxy-alpha-D-glucopyranosyl]-1D-myo-inositol + AMP + diphosphate
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ATP + diphthine-[translation elongation factor 2] + NH3 = AMP + diphosphate + diphthamide-[translation elongation factor 2]
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ATP + 3-dimethylallyl-4-hydroxybenzoate + 3-amino-4,7-dihydroxycoumarin = AMP + diphosphate + 8-demethylnovobiocic acid
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L-histidine + beta-alanine + ATP = carnosine + AMP + diphosphate
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ATP + L-tyrosine + L-arginine = L-tyrosyl-L-arginine + AMP + diphosphate
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ATP + fumarate + (2S)-2,3-diaminopropionate = AMP + diphosphate + (2E)-4-[(2-amino-2-carboxyethyl)amino]-4-oxobut-2-enoate
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ATP + L-isoleucine + acetoacetyl-CoA = AMP + diphosphate + tenuazonic acid + CoA
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ATP + (R)-4'-phosphopantothenate + L-cysteine = AMP + diphosphate + N-[(R)-4'-phosphopantothenoyl]-L-cysteine
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ATP + L-2,3-diaminopropanoate + citrate = AMP + diphosphate + 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate
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ATP + 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + L-2,3-diaminopropanoate = AMP + diphosphate + 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate
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ATP + 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate = AMP + diphosphate + staphyloferrin B
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ATP + N5-[(S)-citryl]-D-ornithine + citrate = AMP + diphosphate + staphyloferrin A
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ATP + D-ornithine + citrate = AMP + diphosphate + N5-[(S)-citryl]-D-ornithine
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ATP + (2S,5S)-5-carboxymethylproline = AMP + diphosphate + (3S,5S)-carbapenam 3-carboxylate
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7-carboxy-7-carbaguanine + NH3 + ATP = 7-cyano-7-carbaguanine + AMP + diphosphate + H2O
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ATP + agmatine + [tRNAIle2]-cytidine34 = [tRNAIle2]-2-agmatinylcytidine34 + AMP + diphosphate
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Substrate in Enzyme-catalyzed Reactions (485 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate = L-2-aminoadipate + NADPH + H+ + ATP
show the reaction diagram
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AMP + phosphate = adenine + alpha-D-ribose 1,5-bisphosphate
show the reaction diagram
dimethylallyl diphosphate + AMP = diphosphate + N6-(dimethylallyl)adenosine phosphate
show the reaction diagram
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AMP + D-fructose 1,6-bisphosphate = ADP + D-fructose 6-phosphate
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ATP + AMP = ADP + ADP
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AMP + H2O = IMP + NH3
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ATP + AMP = ADP + ADP
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ATP + AMP = ADP + ADP
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