Ligand 1,4-androstadiene-3,17-dione

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Basic Ligand Information

Molecular Structure
Picture of 1,4-androstadiene-3,17-dione (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C19H24O2
1,4-androstadiene-3,17-dione
LUJVUUWNAPIQQI-QAGGRKNESA-N
Synonyms:
1,4-androstadien-3,17-dione, 1,4-androstene-3,17-dione, androst-1,4-dien-3,17-dione, androsta-1,4-diene-3,17-dione


Show all pahtways known for Show all BRENDA pathways known for 1,4-androstadiene-3,17-dione

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,4-androstadiene-3,17-dione + 2 O2 + 2 H+ = 9-hydroxy-1,4-androstadiene-3,17-dione + H2O2
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,4-androstadiene-3,17-dione + NADPH + H+ = ? + NADP+
show the reaction diagram
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1,4-androstadiene-3,17-dione + H2O = ?
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1,4-androstadiene-3,17-dione + 2 O2 + 2 H+ = 9-hydroxy-1,4-androstadiene-3,17-dione + H2O2
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5beta-androst-3,17-dione + acceptor = androst-1,4-dien-3,17-dione + reduced acceptor
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (7 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.1027
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References & Links

Links to other databases for 1,4-androstadiene-3,17-dione

ChEBI
PubChem
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PubChem