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Ligand (4S,4aS,5S,7S,7aS,8R,9aS)-5-hydroxy-4a,8-dimethyl-3-methylidene-2-oxododecahydroazuleno[6,5-b]furan-4,7-diyl diacetate
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Basic Ligand Information
C19H26O7
(4S,4aS,5S,7S,7aS,8R,9aS)-5-hydroxy-4a,8-dimethyl-3-methylidene-2-oxododecahydroazuleno[6,5-b]furan-4,7-diyl diacetate
JXEGMONJOSAULB-FPSTYPQSSA-N
2-acetylflexuosin A, 2alpha,6alpha-diacetoxy-4beta-hydroxy-11(13)-pseudoguaien-12,8alpha-olide, britanin, NSC145913
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open all tablesRoles as Enzyme Ligand
Inhibitor in Enzyme-catalyzed Reactions (2 results)
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EC NUMBER 
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibitor directly binds to UbcH5c protein and inhibits cell viability and colony formation, induces apoptosis, and suppresses migration and invasion of pancreatic cancer cells in vitro. The compound inhibits UbcH5c-mediated IkappaBalpha degradation and NF-kappaB activation. The compound suppresses the tumor growth and metastasis in two orthotopic pancreatic tumor mouse models
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inhibitor directly binds to UbcH5c protein and inhibits cell viability and colony formation, induces apoptosis, and suppresses migration and invasion of pancreatic cancer cells in vitro. The compound inhibits UbcH5c-mediated IkappaBalpha degradation and NF-kappaB activation. The compound suppresses the tumor growth and metastasis in two orthotopic pancreatic tumor mouse models
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Enzyme Kinetic Parameters
References & Links
Literature References (1)
Links to other databases for (4S,4aS,5S,7S,7aS,8R,9aS)-5-hydroxy-4a,8-dimethyl-3-methylidene-2-oxododecahydroazuleno[6,5-b]furan-4,7-diyl diacetate
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Release 2026.1 (March 2026)
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