Ligand 5alpha-Cholest-7-en-3beta-ol

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Basic Ligand Information

Molecular Structure
Picture of 5alpha-Cholest-7-en-3beta-ol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C27H46O
5alpha-Cholest-7-en-3beta-ol
IZVFFXVYBHFIHY-SKCNUYALSA-N
Synonyms:
lathosterol


Show all pahtways known for Show all BRENDA pathways known for 5alpha-Cholest-7-en-3beta-ol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
lathosterol + NADPH + H+ = 7-oxocholestanol + cholestanol-7alpha,8alpha-epoxide + NADP+ + H2O
show the reaction diagram
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5alpha-cholest-7-en-3beta-ol + NADP+ = 5alpha-cholesta-7,24-dien-3beta-ol + NADPH + H+
show the reaction diagram
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5alpha-cholest-7-en-3beta-ol = ?
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5alpha-cholesta-7,24-dien-3beta-ol + NADPH = 5alpha-cholest-7-en-3beta-ol + NADP+
show the reaction diagram
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zymostenol = lathosterol
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
lathosterol + NADPH + H+ = 7-oxocholestanol + cholestanol-7alpha,8alpha-epoxide + NADP+ + H2O
show the reaction diagram
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5alpha-cholest-7-en-3beta-ol + NADP+ = 5alpha-cholesta-7,24-dien-3beta-ol + NADPH + H+
show the reaction diagram
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oleoyl-CoA + lathosterol = CoA + lathosteryl oleate
show the reaction diagram
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5alpha-cholest-7-en-3beta-ol + UDP-glucose = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5alpha-cholesta-7,24-dien-3beta-ol + NADPH = 5alpha-cholest-7-en-3beta-ol + NADP+
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
15.5-65% inhibition between 30 and 260 nmol
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (16 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 5alpha-Cholest-7-en-3beta-ol

ChEBI
PubChem
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PubChem