Ligand 4-phospho-D-erythronate

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Basic Ligand Information

Molecular Structure
Picture of 4-phospho-D-erythronate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H9O8P
4-phospho-D-erythronate
ZCZXOHUILRHRQJ-PWNYCUMCSA-N
Synonyms:
4-phosphoerythronate, 4-phosphono-D-erythronate, D-erythro-2,3-dihydroxybutyric acid 3-phosphate, erythronate-4-phosphate, Erythronic acid 4-phosphate


Show all pahtways known for Show all BRENDA pathways known for 4-phospho-D-erythronate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-erythrose 4-phosphate + NAD+ = 4-phosphoerythronate + NADH
show the reaction diagram
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-

Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-phospho-D-erythronate + NAD+ = glycerone phosphate + CO2 + NADH + H+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + D-erythronate = ADP + 4-phospho-D-erythronate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
best inhibitor
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.4
-
in 50 mM Tris-HCl (pH 8.0) with 50 mM NaCl, 1 mM dithiothreitol, at 22°C; pH 8.0, 22°C, recombinant enzyme

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0029
-
in 50 mM Tris-HCl (pH 8.0) with 50 mM NaCl, 1 mM dithiothreitol, at 22°C; pH 8.0, 22°C, recombinant enzyme

Ki Value (7 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
TABLE ID

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
5
-
pH 8.4, 25°C

References & Links

Links to other databases for 4-phospho-D-erythronate

ChEBI
PubChem
ChEBI
PubChem