Ligand L-2,4-diaminobutyric acid

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Basic Ligand Information

Molecular Structure
Picture of L-2,4-diaminobutyric acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H10N2O2
L-2,4-diaminobutyric acid
OGNSCSPNOLGXSM-VKHMYHEASA-N
Synonyms:
(2S)-2,4-diaminobutanoate, L-2,4-diamino-n-butyrate, L-2,4-diaminobutanoate, L-2,4-diaminobutyrate, L-diaminobutyrate


Show all pahtways known for Show all BRENDA pathways known for L-2,4-diaminobutyric acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + L-2,4-diaminobutanoate = CoA + N4-acetyl-L-2,4-diaminobutanoate
show the reaction diagram
L-2,4-diaminobutanoate + pyruvate = L-2-amino-4-oxobutanoate + L-alanine
show the reaction diagram
-
L-2,4-diaminobutanoate = propane-1,3-diamine + CO2
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-2-amino-4-oxobutanoate + L-glutamate = L-2,4-diaminobutanoate + 2-oxoglutarate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (17 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-2,4-diaminobutyric acid + H2O + O2 = 4-amino-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
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pyruvate + L-2,4-diaminobutanoate = L-alanine + ?
show the reaction diagram
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L-2,4-diaminobutanoate = 1,3-diaminopropane + CO2
show the reaction diagram
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L-2,4-Diaminobutyrate = D-2,4-Diaminobutyrate
show the reaction diagram
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ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + L-diaminobutyrate = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-diaminobutyrate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-2-amino-4-oxobutanoate + L-glutamate = L-2,4-diaminobutanoate + 2-oxoglutarate
show the reaction diagram
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N2-acetyl-L-2,4-diaminobutanoate + H2O = L-2,4-diaminobutanoate + acetate
show the reaction diagram
-
-
N4-acetyl-L-diaminobutyric acid + H2O = L-diaminobutyrate + acetate
show the reaction diagram
-
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D-2,4-Diaminobutyrate = L-2,4-Diaminobutyrate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibition
-

3D Structure of Enzyme-Ligand-Complex (PDB) (10 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (10 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.052
-
pH 7.5, 30C

KM Value (24 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.3
-
pH 7.5, 30C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
8.4
-
pH 8.0, 25C, recombinant detagged enzyme

References & Links

Links to other databases for L-2,4-diaminobutyric acid

ChEBI
PubChem
ChEBI
PubChem