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Ligand 3-(2-hydroxyphenyl)pyridin-2(1H)-one

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Inhibitor in Enzyme-catalyzed Reactions (1 result)

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Show Inhibitors (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

2.3.2.23

-

758642

-

Enzyme Kinetic Parameters

IC₅₀ Value (1 result)

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Show IC50 Value (1 entry)

EC NUMBER

IC50 VALUE

IC50 VALUE MAXIMUM

COMMENTARY

LITERATURE

2.3.2.23

20

-

above, pH and temperature not specified in the publication

758642

References & Links

Literature References (1)

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Show Reference (1 entry)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

758642

27038327

Insights into the allosteric inhibition of the SUMO E2 enzyme Ubc9

2016

Hewitt, W.M.; Lountos, G.T.; Zlotkowski, K.; Dahlhauser, S.D.; Saunders, L.B.; Needle, D.; Tropea, J.E.; Zhan, C.; Wei, G.; Ma, B.; Nussinov, R.; Waugh, D.S.; Schneekloth, J.S.

Angew. Chem. Int. Ed. Engl.

55

5703-5707

Links to other databases for 3-(2-hydroxyphenyl)pyridin-2(1H)-one

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Show Links (1 entry)