Ligand 2-amino-5-phenylfuran-3-carbonitrile
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Basic Ligand Information
C11H8N2O
2-amino-5-phenylfuran-3-carbonitrile
UWTDTJWGYWUILP-UHFFFAOYSA-N
Roles as Enzyme Ligand
Inhibitor in Enzyme-catalyzed Reactions (1 result)
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i.e. EM11, about 25% inhibition of FANCD2 ubiquination
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Enzyme Kinetic Parameters
References & Links
Literature References (1)
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Allosteric targeting of the Fanconi anemia ubiquitin-conjugating enzyme Ube2T by fragment screening
2017
Morreale, F.E.; Bortoluzzi, A.; Chaugule, V.K.; Arkinson, C.; Walden, H.; Ciulli, A.
J. Med. Chem.
60
4093-4098
Links to other databases for 2-amino-5-phenylfuran-3-carbonitrile