Ligand UDP-D-xylose

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of UDP-D-xylose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C14H22N2O16P2
UDP-D-xylose
DQQDLYVHOTZLOR-OCIMBMBZSA-N
Synonyms:
UDP-alpha-D-xylopyranose, UDP-alpha-D-xylose, UDP-D-xylopyranose, UDP-xylose, UDPxylose

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (39 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-D-xylose + dolichyl phosphate = UDP + dolichyl D-xylosyl phosphate
show the reaction diagram
-
UDP-D-xylose + flavonol 3-O-glycoside = UDP + flavonol 3-O-D-xylosylglycoside
show the reaction diagram
-
UDP-D-xylose + trans-zeatin = ?
show the reaction diagram
-
UDP-D-xylose + Glcbeta-Ser53-EGF-like domain of bovine factor IX(45-87) = UDP + Xylalpha(1-3)Glcbeta-Ser53-EGF-like domain of bovine factor IX(45-87)
show the reaction diagram
-
UDP-alpha-D-xylose + cyanidin 3-O-beta-D-galactoside = UDP + cyanidin 3-O-(beta-D-xylosyl-(1->2)-beta-D-galactoside)
show the reaction diagram
-
UDP-alpha-D-xylose + kaempferol = UDP + kaempferol 3-O-beta-D-xyloside
show the reaction diagram
-
UDP-alpha-D-xylose + 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man]-Ser/Thr-[protein] = UDP + 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man]-Ser/Thr-[protein]
show the reaction diagram
-
UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine = UDP + [protein with EGF-like domain]-3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-serine
show the reaction diagram
-
UDP-D-xylose = UDP-L-arabinose
show the reaction diagram
-
UDP-D-xylose = UDP-L-arabinose
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UTP + alpha-D-xylose 1-phosphate = diphosphate + UDP-xylose
show the reaction diagram
-
UTP + alpha-D-xylose 1-phosphate = diphosphate + UDP-D-xylose
show the reaction diagram
-
-
UDP-D-glucuronate = UDP-D-xylose + CO2
show the reaction diagram
-
UDP-L-arabinose = UDP-D-xylose
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (241 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-alpha-D-xylose + D-fructose = ?
show the reaction diagram
-
UDP-xylose + 4-methylumbelliferyl-beta-D-xylopyranoside = ?
show the reaction diagram
-
UDPxylose + luteolin = UDP + luteolin 7-O-xyloside
show the reaction diagram
-
UDP-xylose + luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] = UDP + luteolin 7-O-[beta-D-glucuronosyl-1,2-beta-D-glucuronide]-4'-O-beta-D-xyloside
show the reaction diagram
-
UDP-alpha-D-xylose + cyanidin 3-O-beta-D-glucoside = UDP + cyanidin 3-O-glucosyl-2''-O-alpha-D-xyloside
show the reaction diagram
-
UDP-xylose + 4-methylumbelliferone = UDP + 4-methylumbelliferyl beta-D-xyloside
show the reaction diagram
-
UDP-alpha-D-xylose + phloretin = ?
show the reaction diagram
-
UDP-xylose + 4-methylumbelliferyl beta-D-xylopyranoside = UDP + ?
show the reaction diagram
-
UDP-xylose + quercetin = UDP + quercetin 3-O-beta-D-xylose
show the reaction diagram
-
UDP-D-xylose + dolichyl phosphate = UDP + dolichyl D-xylosyl phosphate
show the reaction diagram
-
UDP-alpha-D-xylose + cyanidin 3-O-beta-D-galactoside = UDP + cyanidin 3-O-(beta-D-xylosyl-(1->2)-beta-D-galactoside)
show the reaction diagram
-
diphosphate + UDP-xylose = ?
show the reaction diagram
-
UDP-xylose + phosphate = UDP + D-xylose 1-phosphate
show the reaction diagram
-
diphosphate + UDP-xylose = UTP + D-xylose 1-phosphate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UTP + alpha-D-xylose 1-phosphate = diphosphate + UDP-xylose
show the reaction diagram
-
UDP-L-arabinose = UDP-D-xylose
show the reaction diagram
-
-

Activator in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activation of epicotyl and cotyledon isozymes
-

Inhibitor in Enzyme-catalyzed Reactions (69 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
strong inhibition
-
weak inhibition
-
1 mM, about 20% inhibition
-
above 0.03 mM
-
inhibition or chenodeoxycholic acid and testosterone glucuronidation
-
competitive inhibitor to glucosylation of glycogenin by UDP-glucose
-
UDP-galactose or UDP-glucose synthesis
-

3D Structure of Enzyme-Ligand-Complex (PDB) (39 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (12 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
3
6
in 100 mM cacodylate buffer, pH 7.0 containing 10 mM MnCl2 and 0.2-6 microM purified fusion-beta1,4-GalT7
0.01
-
purified maltose-binding protein-beta1,4-GalT7, in 100 mM cacodylate buffer (pH 7.0) containing 10 mM MnCl2, at 37°C

KM Value (35 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.13
-
in 100 mM cacodylate buffer, pH 7.0 containing 10 mM MnCl2 and 0.2-6 microM purified fusion-beta1,4-GalT7
2.7
-
-
0.4
-
-
0.16
-
purified maltose-binding protein-beta1,4-GalT7, in 100 mM cacodylate buffer (pH 7.0) containing 10 mM MnCl2, at 37°C
0.00055
-
-
0.13
-
pH 7.0, 37°C, recombinant mutant DELTA39 XylT
0.003
-
-
0.2
-
pH 7.5, 32°C, crude enzyme
0.025
-
pH 7.5, 30°C, cosubstrate: kaempferol
0.28
-
pH 7.2, 37°C

Ki Value (11 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for UDP-D-xylose

ChEBI
PubChem
-
PubChem