Ligand S-adenosylmethioninamine

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Basic Ligand Information

Molecular Structure
Picture of S-adenosylmethioninamine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C14H23N6O3S
S-adenosylmethioninamine
ZUNBITIXDCPNSD-LSRJEVITSA-N
Synonyms:
(5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium, (5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium salt, (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt, 5'-deoxy-5'-[methyl-(3-aminopropyl)-sulfonio]-adenosine, decarboxylated adenosylmethionine, S-5'-deoxyadenosyl-(5')-3-methylthiopropylamine, S-adenosyl-(5')-3-methylthio-1-propylamine, S-adenosyl-(5')-3-methylthiopropylamine, S-adenosyl-3-methylthio-1-propylamine, S-adenosyl-L-methioninamine, S-adenosyl-L-methionineamine, S-adenosyl 3-(methylsulfanyl)propylamine, S-adenosyl 3-(methylthio)propylamine, S-methyladenosylhomocysteamine


Show all pahtways known for Show all BRENDA pathways known for S-adenosylmethioninamine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (26 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 S-adenosyl 3-(methylthio)propylamine + spermidine = 2 S-methyl-5'-thioadenosine + N4-bis(aminopropyl)spermidine
show the reaction diagram
-
S-adenosylmethioninamine + propane-1,3-diamine = 5'-methylthioadenosine + N-(3-aminopropyl)-1,3-diaminopropane
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (78 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-(5')-3-methylthiopropylamine + 8-amino-7-oxononanoate = ? + (7S,8R)-diaminononanoate
show the reaction diagram
-
(5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium + CO2 = S-adenosyl-L-methionine + H+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (16 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.73
-
pH 9.0, 37°C
0.016
-
pH 9.0, recombinant wild-type enzyme and mutant R253K

KM Value (34 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.64
-
pH 9.0, 37°C
0.0079
-
pH 7.5, 78°C
0.091
-
-

References & Links

Links to other databases for S-adenosylmethioninamine

ChEBI
PubChem
ChEBI
PubChem