Ligand methane

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Basic Ligand Information

Molecular Structure
Picture of methane (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
CH4
methane
VNWKTOKETHGBQD-UHFFFAOYSA-N
Synonyms:
2-(3-[[(3-fluorophenyl)methyl]amino]propyl)phenol, CH4

Show all pahtways known for Show all pathways known for methane

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic-phosphate 5-phosphate + methane
show the reaction diagram
-
-
CH3Hg+ + H+ = CH4 + Hg2+
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
methane + NADH + H+ + O2 = methanol + NAD+ + H2O
show the reaction diagram
-
methane + NADPH + H+ + O2 = methanol + NADP+ + H2O
show the reaction diagram
-
CoM-S-S-CoB + methane = methyl-CoM + CoB
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (25 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic-phosphate 5-phosphate + methane
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.3
-
pH 7.2, 25C
3.7
-
-

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.1
-
pH 7.2, 25C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
3.24
-
value derived from slope replot

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.00037
-
at pH 7.4 and 25C

References & Links

Links to other databases for methane

ChEBI
PubChem
ChEBI
PubChem