Ligand (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate

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Basic Ligand Information

Molecular Structure
Picture of (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C11H16BrN2O14P3
(E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate
BDKFDDMJXWAXHI-PIXDULNESA-N

Roles as Enzyme Ligand

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50: 0.0069 mM, reaction with thymidine, fusion protein with glutathione S-transferase. The inhibitor is efficiently metabolized to its 5'-mono-, 5'-di- and 5'-triphosphate derivatives in the insect cell culture and abundently incorporated into the insect cell DNA
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Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.005
-
-

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0069
-
IC50: 0.0069 mM, reaction with thymidine, fusion protein with glutathione S-transferase. The inhibitor is efficiently metabolized to its 5'-mono-, 5'-di- and 5'-triphosphate derivatives in the insect cell culture and abundently incorporated into the insec

References & Links

Links to other databases for (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate

ChEBI
PubChem
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PubChem