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Ligand 2'-O-succinyl-ADP-ribose

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (10 results)

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Show Natural Product (10 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.286

NAD+ + [protein]-N6-succinyl-L-lysine + H2O = nicotinamide + [protein]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [carbamoyl phosphate synthase 1]-N6-succinyl-L-lysine + H2O = nicotinamide + [carbamoyl phosphate synthase 1]-L-lysine + 2'-O-succinyl-ADP ribose

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2.3.1.B43

NAD+ + [ATP synthase]-N6-succinyl-L-lysine + H2O = nicotinamide + [ATP synthase]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [Cu/Zn superoxide dismutase]-N6-succinyl-L-lysine123 + H2O = nicotinamide + [Cu/Zn superoxide dismutase]-L-lysine123 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [glucose 6-phosphate dehydrogenase]-N6-succinyl-L-lysine + H2O = nicotinamide + [glucose 6-phosphate dehydrogenase]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [glutaminase]-N6-succinyl-L-lysine + H2O = nicotinamide + [glutaminase]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H2B]-N6-succinyl-L-lysine9 + H2O = nicotinamide + [histone H2B]-L-lysine9 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [IDH2]-N6-succinyl-L-lysine + H2O = nicotinamide + [IDH2]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [protein]-N6-succinyl-L-lysine + H2O = nicotinamide + [protein]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [pyruvate kinase M2]-N6-succinyl-L-lysine311 + H2O = nicotinamide + [pyruvate kinase M2]-L-lysine311 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

9 entries

Product in Enzyme-catalyzed Reactions (44 results)

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Show Product (44 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.286

NAD+ + N2-benzyloxycarbonyl-N6-succinyl-L-lysine-7-amido-4-methylcoumarin = nicotinamide + N2-benzyloxycarbonyl-L-lysine-7-amido-4-methylcoumarin + 2'-O-succinyl-ADP ribose

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2.3.1.286

NAD+ + N2-benzyloxycarbonyl-N6-succinyl-L-lysine-7-amido-4-methylcoumarin + H2O = nicotinamide + N2-benzyloxycarbonyl-L-lysine-7-amido-4-methylcoumarin + 2'-O-succinyl-ADP-ribose

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2.3.1.286

NAD+ + QTAR(N6-succinyl)KSTGG + H2O = nicotinamide + QTARKSTGG + 2'-O-succinyl-ADP-ribose

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2.3.1.286

NAD+ + [protein]-N6-succinyl-L-lysine + H2O = nicotinamide + [protein]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [carbamoyl phosphate synthase 1]-N6-succinyl-L-lysine + H2O = nicotinamide + [carbamoyl phosphate synthase 1]-L-lysine + 2'-O-succinyl-ADP ribose

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2.3.1.B43

NAD+ + Ac-(N6-succinyl)Lys-7-amido-4-methylcoumarin + H2O = nicotinamide + Ac-Lys-7-amido-4-methylcoumarin + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + Ac-Leu-Gly-(N6-succinyl)Lys-7-amido-4-methylcoumarin + H2O = nicotinamide + Ac-Leu-Gly-Lys-7-amido-4-methylcoumarin + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + benzoyl-GVL(N6-succinyl)KEYGV-amide + H2O = nicotinamide + benzoyl-GVLKEYGV-amide + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + benzyl-(N6-succinyl)Lys-7-amido-4-methylcoumarin + H2O = nicotinamide + benzyl-Lys-7-amido-4-methylcoumarin + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + ETGVDLT(N6-succinyl)KDNMALQR + H2O = nicotinamide + ETGVDLTKDNMALQR + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + KGLGKGGA(N6-succinyl)KRHRKW + H2O = nicotinamide + KGLGKGGAKRHRKW + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + KQTAR(N6-succinyl)KSTGGKA + H2O = nicotinamide + KQTARKSTGGKA + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + KQTAR(N6-succinyl)KSTGGWW + H2O = nicotinamide + KQTARKSTGGWW + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + KTRSG(N6-succinyl)KVMRRWW + H2O = nicotinamide + KTRSGKVMRRWW + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + N2-benzyloxycarbonyl-N6-succinyl-L-lysine-7-amido-4-methylcoumarin + H2O = nicotinamide + N2-benzyloxycarbonyl-L-lysine-7-amido-4-methylcoumarin + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + QTAR(N6-succinyl)KSTGG + H2O = nicotinamide + QTARKSTGG + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + SGASE(N6-succinyl)KDIVHSGWW + H2O = nicotinamide + SGASEKDIVHSGWW + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + SQG(N6-succinyl)KVLQATVV + H2O = nicotinamide + SQGKVLQATVV + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + VLLPEYGGT(N6-succinyl)KVVLDDK + H2O = nicotinamide + VLLPEYGGTKVVLDDK + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [ATP synthase]-N6-succinyl-L-lysine + H2O = nicotinamide + [ATP synthase]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [Cu/Zn superoxide dismutase]-N6-succinyl-L-lysine123 + H2O = nicotinamide + [Cu/Zn superoxide dismutase]-L-lysine123 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [glucose 6-phosphate dehydrogenase]-N6-succinyl-L-lysine + H2O = nicotinamide + [glucose 6-phosphate dehydrogenase]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [glutaminase]-N6-succinyl-L-lysine + H2O = nicotinamide + [glutaminase]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H2A]-N6-succinyl-L-lysine95 + H2O = nicotinamide + [histone H2A]-L-lysine95 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H2A]-N6-succinyl-L-lysine9_(4-15)-A10G peptide + H2O = nicotinamide + [histone H2A]-L-lysine9_(4-15)-A10G peptide + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H2B]-N6-succinyl-L-lysine116 + H2O = nicotinamide + [histone H2B]-L-lysine116 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H2B]-N6-succinyl-L-lysine120 + H2O = nicotinamide + [histone H2B]-L-lysine120 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H2B]-N6-succinyl-L-lysine34 + H2O = nicotinamide + [histone H2B]-L-lysine34 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H2B]-N6-succinyl-L-lysine9 + H2O = nicotinamide + [histone H2B]-L-lysine9 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H3 K9 peptide]-N6-succinyl-L-lysine + H2O = nicotinamide + [histone H3 K9 peptide]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H3]-N6-succinyl-L-lysine122 + H2O = nicotinamide + [histone H3]-L-lysine122 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H3]-N6-succinyl-L-lysine14 + H2O = nicotinamide + [histone H3]-L-lysine14 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H3]-N6-succinyl-L-lysine14_(9-20)-A15G peptide + H2O = nicotinamide + [histone H3]-L-lysine14_(9-20)-A15G peptide + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H3]-N6-succinyl-L-lysine56 + H2O = nicotinamide + [histone H3]-L-lysine56 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H3]-N6-succinyl-L-lysine79 + H2O = nicotinamide + [histone H3]-L-lysine79 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H3]-N6-succinyl-L-lysine9 + H2O = nicotinamide + [histone H3]-L-lysine9 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H4]-N6-succinyl-L-lysine12 + H2O = nicotinamide + [histone H4]-L-lysine12 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H4]-N6-succinyl-L-lysine31 + H2O = nicotinamide + [histone H4]-L-lysine31 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H4]-N6-succinyl-L-lysine31_(26-37)-P32A peptide + H2O = nicotinamide + [histone H4]-L-lysine31_(26-37)-P32A peptide + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H4]-N6-succinyl-L-lysine77 + H2O = nicotinamide + [histone H4]-L-lysine77 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [histone H4]-N6-succinyl-L-lysine91 + H2O = nicotinamide + [histone H4]-L-lysine91 + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [IDH2]-N6-succinyl-L-lysine + H2O = nicotinamide + [IDH2]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [protein]-N6-succinyl-L-lysine + H2O = nicotinamide + [protein]-L-lysine + 2'-O-succinyl-ADP-ribose

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2.3.1.B43

NAD+ + [pyruvate kinase M2]-N6-succinyl-L-lysine311 + H2O = nicotinamide + [pyruvate kinase M2]-L-lysine311 + 2'-O-succinyl-ADP-ribose

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2.3.1.286

4 entries

2.3.1.B43

40 entries

Enzyme Kinetic Parameters

References & Links

Literature References (0)

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Links to other databases for 2'-O-succinyl-ADP-ribose

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