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Ligand O-acetyl-ADP-ribose

Basic Ligand Information

Molecular Structure

Related pathways

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Natural Substrate (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.2.2.19

2'-O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate

682516

-

3.2.2.19

O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate

731708

-

3.2.2.19

2 entries

In Vivo Product in Enzyme-catalyzed Reactions (36 results)

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Show Natural Product (36 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.286

NAD+ + [chicken erythrocyte histone]-N6-acetyl-L-lysine = nicotinamide + [protein]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + [nuclear receptor LXR]-N6-acetyl-L-lysine = nicotinamide + [nuclear receptor LXR]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + [p53 protein]-N6-acetyl-L-lysine382 = nicotinamide + [p53 protein]-L-lysine382 + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + [SREBP-1c]-N6-acetyl-L-lysine = nicotinamide + [SREBP-1c]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + [DNA repair factor Ku70]-N6-acetyl-L-lysine382 = nicotinamide + [DNA repair factor Ku70]-L-lysine382 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [glutamate dehydrogenase]-N6-acetyl-L-lysine = nicotinamide + [glutamate dehydrogenase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [heat shock protein 10]-N6-acetyl-L-lysine56 = nicotinamide + [heat shock protein 10]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [histone H4]-N6-acetyl-L-lysine16 + H2O = nicotinamide + [histone H4]-L-lysine16 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [isocitrate dehydrogenase 2]-N6-acetyl-L-lysine + H2O = nicotinamide + [isocitrate dehydrogenase 2]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [isocitrate dehydrogenase 2]-N6-acetyl-L-lysine413 = nicotinamide + [isocitrate dehydrogenase 2]-L-lysine413 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [p53 protein]-N6-acetyl-L-lysine = nicotinamide + [p53 protein]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [PER2 protein]-N6-acetyl-L-lysine = nicotinamide + [PER2 protein]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [protein]-N6-acetyl-L-lysine + H2O = nicotinamide + [protein]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [thymine DNA glycosylase]-N6-acetyl-L-lysine = nicotinamide + [thymine DNA glycosylase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [very long-chain acyl-CoA dehydrogenase]-N6-acetyl-L-lysine = nicotinamide + [very long-chain acyl-CoA dehydrogenase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + [histone H3]-N6-acetyl-L-lysine18 = nicotinamide + [histone H3]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + [histone H3]-N6-acetyl-L-lysine56 = nicotinamide + [histone H3]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + [histone H3]-N6-acetyl-L-lysine9 = nicotinamide + [histone H3]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + [Per2]-N6-acetyl-L-lysine = nicotinamide + [Per2]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + [histone H3 peptide]-N6-acetyl-L-lysine18 = nicotinamide + [histone H3 peptide]-L-lysine18 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + [histone H3 peptide]-N6-acetyl-L-lysine9 = nicotinamide + [histone H3 peptide]-L-lysine9 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + [histone H3]-N6-acetyl-L-lysine = nicotinamide + [histone H3]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + [histone H4]-N6-acetyl-L-lysine = nicotinamide + [histone H4]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [carbamoyl phosphate synthase 1]-N6-acetyl-L-lysine + H2O = nicotinamide + [carbamoyl phosphate synthase 1]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B43

NAD+ + [carbamoyl phosphate synthetase 1]-N6-acetyl-L-lysine + H2O = nicotinamide + [carbamoyl phosphate synthetase 1]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B43

NAD+ + [acetyl-coenzyme A synthetase]-N6-acetyl-L-lysine609 + H2O = nicotinamide + [acetyl-coenzyme A synthetase]-L-lysine609 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [carbamoyl phosphate synthase 1]-N6-acetyl-L-lysine + H2O = nicotinamide + [carbamoyl phosphate synthase 1]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [forkhead box O3]-N6-acetyl-L-lysine + H2O = nicotinamide + [forkhead box O3]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [glucose-6-phosphate dehydrogenase]-N6-acetyl-L-lysine + H2O = nicotinamide + [glucose-6-phosphate dehydrogenase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [histone H4]-N6-acetyl-L-lysine16 + H2O = nicotinamide + [histone H4]-L-lysine16 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [isocitrate dehydrogenase 2]-N6-acetyl-L-lysine + H2O = nicotinamide + [isocitrate dehydrogenase 2]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [N-hydroxyarylamine O-acetyltransferase]-N6-acetyl-L-lysine + H2O = nicotinamide + [N-hydroxyarylamine O-acetyltransferase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [protein]-N6-acetyl-L-lysine + H2O = nicotinamide + [protein]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [RcsB protein]-N6-acetyl-L-lysine180 + H2O = nicotinamide + [RcsB protein]-L-lysine180 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [response regulator CheY]-N6-acetyl-L-lysine + H2O = nicotinamide + [response regulator CheY]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [urate oxidase]-N6-acetyl-L-lysine + H2O = nicotinamide + [urate oxidase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

15 entries

2.3.1.B41

8 entries

2.3.1.B43

13 entries

Substrate in Enzyme-catalyzed Reactions (4 results)

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Show Substrate (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.2.1.143

2'-O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate

682516

-

3.2.2.19

2'-O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate

682516

-

3.2.2.19

O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate

731708

-

3.2.2.19

2 entries

3.6.1.13

2''-O-acetyl-ADP-ribose + H2O = AMP + 2-O-acetyl-D-ribose 5-phosphate

740674

-

Product in Enzyme-catalyzed Reactions (72 results)

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Show Product (72 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.286

NAD+ + [alpha-tubulin]-N6-acetyl-L-lysine40 = nicotinamide + [alpha-tubulin]-L-lysine40 + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + [chicken erythrocyte histone]-N6-acetyl-L-lysine = nicotinamide + [protein]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + [nuclear receptor LXRalpha]-N6-acetyl-L-lysine432 = nicotinamide + [nuclear receptor LXRalpha]-L-lysine432 + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + [nuclear receptor LXRbeta]-N6-acetyl-L-lysine433 = nicotinamide + [nuclear receptor LXRbeta]-L-lysine433 + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + [nuclear receptor LXR]-N6-acetyl-L-lysine = nicotinamide + [nuclear receptor LXR]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + [p53 protein]-N6-acetyl-L-lysine382 = nicotinamide + [p53 protein]-L-lysine382 + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + [SREBP-1c]-N6-acetyl-L-lysine = nicotinamide + [SREBP-1c]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.286

NAD+ + QTAR(N6-acetyl)KSTGG + H2O = nicotinamide + QTARKSTGG + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + TRSG(N6-acetyl)KVMR + H2O = nicotinamide + TRSGKVMR + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + TRSG(N6-acetyl)KVMRRLLR = nicotinamide + TRSGKVMRRLLR + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [alpha-tubulin peptide]-N6-acetyl-L-lysine = nicotinamide + [alpha-tubulin peptide]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [DNA repair factor Ku70]-N6-acetyl-L-lysine382 = nicotinamide + [DNA repair factor Ku70]-L-lysine382 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [Fluor de Lys]-N6-acetyl-L-lysine = nicotinamide + [Fluor de Lys]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [glutamate dehydrogenase]-N6-acetyl-L-lysine = nicotinamide + [glutamate dehydrogenase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [heat shock protein 10]-N6-acetyl-L-lysine56 = nicotinamide + [heat shock protein 10]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [histone H2B]-N6-acetyl-L-lysine12 = nicotinamide + [histone H2B]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [histone H3]-N6-acetyl-L-lysine9 = nicotinamide + [histone H3]-L-lysine9 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [histone H4]-N6-acetyl-L-lysine16 + H2O = nicotinamide + [histone H4]-L-lysine16 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [histone H4]-N6-acetyl-L-lysine8 = nicotinamide + [histone H4]-L-lysine8 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [isocitrate dehydrogenase 2]-N6-acetyl-L-lysine + H2O = nicotinamide + [isocitrate dehydrogenase 2]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [isocitrate dehydrogenase 2]-N6-acetyl-L-lysine413 = nicotinamide + [isocitrate dehydrogenase 2]-L-lysine413 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [p53 protein]-N6-acetyl-L-lysine = nicotinamide + [p53 protein]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [PER2 protein]-N6-acetyl-L-lysine = nicotinamide + [PER2 protein]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [protein]-N6-acetyl-L-lysine + H2O = nicotinamide + [protein]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [thymine DNA glycosylase]-N6-acetyl-L-lysine = nicotinamide + [thymine DNA glycosylase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

NAD+ + [very long-chain acyl-CoA dehydrogenase]-N6-acetyl-L-lysine = nicotinamide + [very long-chain acyl-CoA dehydrogenase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + [histone 3]-N6-acetyl-L-lysine9 = nicotinamide + [histone 3]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + [histone H3]-N6-acetyl-L-lysine = nicotinamide + [histone H3]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + [histone H3]-N6-acetyl-L-lysine18 = nicotinamide + [histone H3]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + [histone H3]-N6-acetyl-L-lysine56 = nicotinamide + [histone H3]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + [histone H3]-N6-acetyl-L-lysine9 = nicotinamide + [histone H3]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + [Per2]-N6-acetyl-L-lysine = nicotinamide + [Per2]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + [tumor necrosis factor-alpha]-N6-acetyl-L-lysine9 = nicotinamide + [tumor necrosis factor-alpha]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B41

NAD+ + Ac-AK(N6-acetyl)K-7-amido-4-methylcoumarin = nicotinamide + Ac-AKK-7-amido-4-methylcoumarin + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + Ac-HK(N6-acetyl)K-7-amido-4-methylcoumarin = nicotinamide + Ac-HKK-7-amido-4-methylcoumarin + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + Ac-RHK(N6-acetyl)K-7-amido-4-methylcoumarin = nicotinamide + Ac-RHKK-7-amido-4-methylcoumarin + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + Ac-RYQ(N6-acetyl)K-7-amido-4-methylcoumarin = nicotinamide + Ac-RYQK-7-amido-4-methylcoumarin + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + Ac-TAR(N6-acetyl)K-7-amido-4-methylcoumarin = nicotinamide + Ac-TARK-7-amido-4-methylcoumarin + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + KGLGKGGA(N6-acetyl)KRHRKW + H2O = nicotinamide + KGLGKGGAKRHRKW + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + SKEYFS(N6-acetyl)KQK = nicotinamide + SKEYFSKQK + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + [histone H3 peptide]-N6-acetyl-L-lysine = nicotinamide + [histone H3 peptide]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + [histone H3 peptide]-N6-acetyl-L-lysine18 = nicotinamide + [histone H3 peptide]-L-lysine18 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + [histone H3 peptide]-N6-acetyl-L-lysine9 = nicotinamide + [histone H3 peptide]-L-lysine9 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + [histone H3]-N6-acetyl-L-lysine = nicotinamide + [histone H3]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B41

NAD+ + [histone H4]-N6-acetyl-L-lysine = nicotinamide + [histone H4]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [carbamoyl phosphate synthase 1]-N6-acetyl-L-lysine + H2O = nicotinamide + [carbamoyl phosphate synthase 1]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B43

NAD+ + [carbamoyl phosphate synthetase 1]-N6-acetyl-L-lysine + H2O = nicotinamide + [carbamoyl phosphate synthetase 1]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B43

NAD+ + [PrpE protein]-N6-acetyl-L-lysine + H2O = nicotinamide + [PrpE protein]-L-lysine + 2'-O-acetyl-ADP ribose

-

-

2.3.1.B43

NAD+ + benzoyl-GVL(N6-acetyl)KEYGV-amide + H2O = nicotinamide + benzoyl-GVLKEYGV-amide + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + benzoyl-RGVL(N6-succinyl)KEYGV-amide + H2O = nicotinamide + benzoyl-RGVLKEYGV-amide + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + FKRGVL(N6-acetyl)KEYGVKV + H2O = nicotinamide + FKRGVLKEYGVKV + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + KGLGKGGA(N6-acetyl)KRHRKW + H2O = nicotinamide + KGLGKGGAKRHRKW + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + QTAR(N6-acetyl)KSTGG + H2O = nicotinamide + QTARKSTGG + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + SKEYFS(N6-succinyl)KQK + H2O = nicotinamide + SKEYFSKQK + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + TRSG(N6-acetyl)KVMR + H2O = nicotinamide + TRSGKVMR + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [acetyl-coenzyme A synthetase]-N6-acetyl-L-lysine609 + H2O = nicotinamide + [acetyl-coenzyme A synthetase]-L-lysine609 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [bovine serum albumin]-N6-acetyl-L-lysine + H2O = nicotinamide + [bovine serum albumin]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [carbamoyl phosphate synthase 1]-N6-acetyl-L-lysine + H2O = nicotinamide + [carbamoyl phosphate synthase 1]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [carbamoyl phosphate synthetase 1 derived glutarylated peptide]-N6-acetyl-L-lysine + H2O = nicotinamide + [carbamoyl phosphate synthetase 1 derived glutarylated peptide]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [chicken histone]-N6-acetyl-L-lysine + H2O = nicotinamide + [chicken histone]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [cytochrome c]-N6-acetyl-L-lysine + H2O = nicotinamide + [cytochrome c]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [forkhead box O3]-N6-acetyl-L-lysine + H2O = nicotinamide + [forkhead box O3]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [glucose-6-phosphate dehydrogenase]-N6-acetyl-L-lysine + H2O = nicotinamide + [glucose-6-phosphate dehydrogenase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [histone H3 K9 peptide]-N6-acetyl-L-lysine + H2O = nicotinamide + [histone H3 K9 peptide]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [histone H4]-N6-acetyl-L-lysine16 + H2O = nicotinamide + [histone H4]-L-lysine16 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [isocitrate dehydrogenase 2]-N6-acetyl-L-lysine + H2O = nicotinamide + [isocitrate dehydrogenase 2]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [N-hydroxyarylamine O-acetyltransferase]-N6-acetyl-L-lysine + H2O = nicotinamide + [N-hydroxyarylamine O-acetyltransferase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [peptide derived from carbamoyl phosphate synthetase 1]-N6-acetyl-L-lysine + H2O = nicotinamide + [peptide derived from carbamoyl phosphate synthetase 1]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [protein]-N6-acetyl-L-lysine + H2O = nicotinamide + [protein]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [RcsB protein]-N6-acetyl-L-lysine180 + H2O = nicotinamide + [RcsB protein]-L-lysine180 + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [response regulator CheY]-N6-acetyl-L-lysine + H2O = nicotinamide + [response regulator CheY]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.B43

NAD+ + [urate oxidase]-N6-acetyl-L-lysine + H2O = nicotinamide + [urate oxidase]-L-lysine + 2'-O-acetyl-ADP-ribose

-

-

2.3.1.286

26 entries

2.3.1.B41

19 entries

2.3.1.B43

27 entries

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (1 result)

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Show Turnover Number (1 entry)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

3.6.1.13

0.78

-

at pH 7.5 and 37°C

740674

K_M Value (1 result)

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Show KM Value (1 entry)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

3.6.1.13

0.045

-

at pH 7.5 and 37°C

740674

References & Links

Literature References (3)

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Show Reference (3 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

682516

17075046

The 39-kDa poly(ADP-ribose) glycohydrolase ARH3 hydrolyzes O-acetyl-ADP-ribose, a product of the Sir2 family of acetyl-histone deacetylases

2006

Ono, T.; Kasamatsu, A.; Oka, S.; Moss, J.

Proc. Natl. Acad. Sci. USA

103

16687-16691

731708

24746921

Structure and function of the ARH family of ADP-ribosyl-acceptor hydrolases

2014

Mashimo, M.; Kato, J.; Moss, J.

DNA Repair

23

88-94

740674

12370179

Analysis of O-acetyl-ADP-ribose as a target for Nudix ADP-ribose hydrolases

2002

Rafty, L.A.; Schmidt, M.T.; Perraud, A.L.; Scharenberg, A.M.; Denu, J.M.

J. Biol. Chem.

277

47114-47122

Links to other databases for O-acetyl-ADP-ribose

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