Ligand sophoraflavanone G
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Basic Ligand Information
Molecular Structure

C25H28O6
sophoraflavanone G
XRYVAQQLDYTHCL-WNSKOXEYSA-N
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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dimethylallyl diphosphate + leachianone G = diphosphate + sophoraflavanone G
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Product in Enzyme-catalyzed Reactions (1 result)
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dimethylallyl diphosphate + leachianone G = diphosphate + sophoraflavanone G
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Inhibitor in Enzyme-catalyzed Reactions (2 results)
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from the root of Sophora flavescens, exhibits potent antibacterial activity, noncompetitive inhibitor
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shows inhibitory effects on the bone resorption process related to cathepsin K
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Enzyme Kinetic Parameters
Ki Value (1 result)
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IC50 Value (2 results)
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0.0272
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pH and temperature not specified in the publication
References & Links
Literature References (2)
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Kurarinol, tyrosinase inhibitor isolated from the root of Sophora flavescens
2008
Ryu, Y.B.; Westwood, I.M.; Kang, N.S.; Kim, H.Y.; Kim, J.H.; Moon, Y.H.; Park, K.H.
Phytomedicine
15
612-618
Discovery of a new class of cathepsin K inhibitors in Rhizoma Drynariae as potential candidates for the treatment of osteoporosis
2016
Qiu, Z.C.; Dong, X.L.; Dai, Y.; Xiao, G.K.; Wang, X.L.; Wong, K.C.; Wong, M.S.; Yao, X.S.
Int. J. Mol. Sci.
17
E2116
Links to other databases for sophoraflavanone G