Any feedback?
Please rate this page
(ligand.php)
(0/150)

BRENDA support

Ligand diphosphoric acid

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of diphosphoric acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
H4O7P2
diphosphoric acid
XPPKVPWEQAFLFU-UHFFFAOYSA-N
Synonyms:
(phosphate)2, diphosphate, P2O74-, Pyrophosphate, pyrophosphoric acid
Pathway Source
Pathways
BRENDA
(5R)-carbapenem carboxylate biosynthesis, 3-phenylpropionate degradation, 6-hydroxymethyl-dihydropterin diphosphate biosynthesis, acetate fermentation, adipate degradation more
MetaCyc
(+)-camphor biosynthesis, (-)-camphor biosynthesis, (-)-microperfuranone biosynthesis, (2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis, (3E)-4,8-dimethylnona-1,3,7-triene biosynthesis I more


Show all pahtways known for Show all BRENDA pathways known for diphosphoric acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (102 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O
show the reaction diagram
-
beta-nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
show the reaction diagram
-
UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate
show the reaction diagram
diphosphate + L-serine = phosphate + O-phospho-L-serine
show the reaction diagram
-
diphosphate + GDP-mannose = GTP + alpha-D-mannose 1-phosphate
show the reaction diagram
dTDP-glucose + diphosphate = dTTP + alpha-D-glucose 1-phosphate
show the reaction diagram
diphosphate + CDP-diacylglycerol = CTP + phosphatidate
show the reaction diagram
-
a tRNA with a 3' CCA end + 3 diphosphate = a tRNA precursor + 2 CTP + ATP
show the reaction diagram
UDP-D-glucose + diphosphate = UTP + alpha-D-glucose 1-phosphate
show the reaction diagram
diphosphate + ADP-D-ribose = ATP + D-ribose 5-phosphate
show the reaction diagram
-
AMP + phosphoenolpyruvate + diphosphate = ATP + pyruvate + phosphate
show the reaction diagram
-
diphosphate + microsomal polypeptides = phosphate + phosphorylated microsomal polypeptides
show the reaction diagram
-
diphosphate + H2O = 2 phosphate
show the reaction diagram
-
diphosphate + H2O = 2 phosphate
show the reaction diagram
-
diphosphate + H2O = 2 phosphate
show the reaction diagram
-
AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine = ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine
show the reaction diagram
-
CMP + diphosphate + N-[(R)-4'-phosphopantothenoyl]-L-cysteine = CTP + (R)-4'-phosphopantothenate + L-cysteine
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1922 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Arachnocampa luciferin + O2 + ATP = Arachnocampa oxyluciferin + CO2 + AMP + diphosphate + hv
show the reaction diagram
-
luciferin + O2 + ATP = oxyluciferin + AMP + diphosphate + CO2 + light
show the reaction diagram
-
luciferin + O2 + ATP = oxyluciferin + AMP + diphosphate + CO2 + light
show the reaction diagram
-
L-tyrosine + NADPH + H+ + ATP = L-tyrosinal + NADP+ + AMP + diphosphate
show the reaction diagram
-
L-2-aminoadipate + NADPH + H+ + ATP = (S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
show the reaction diagram
-
presqualene diphosphate + NADPH + H+ = squalene + diphosphate + NADP+
show the reaction diagram
-
trans,octacis-decaprenyl phosphate + 5-phospho-alpha-D-ribose 1-diphosphate = trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate + diphosphate
show the reaction diagram
-
neamine + 5-phospho-alpha-D-ribose 1-diphosphate = 5''-phosphoribostamycin + diphosphate
show the reaction diagram
-
fumigaclavine A + dimethylallyl diphosphate = fumigaclavine C + diphosphate
show the reaction diagram
-
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-(beta-D-ribofuranosyl)aniline 5'-phosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate
show the reaction diagram
-
dimethylallyl diphosphate + 12alpha,13alpha-dihydroxyfumitremorgin C = diphosphate + fumitremorgin B
show the reaction diagram
-
dimethylallyl diphosphate + 4-hydroxyphenylpyruvate = diphosphate + 3-dimethylallyl-4-hydroxyphenylpyruvate
show the reaction diagram
-
geranylgeranyl diphosphate + homogentisate = diphosphate + 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2
show the reaction diagram
-
dimethylallyl diphosphate + 5,10-dihydrophenazine 1-carboxylate = diphosphate + 5,10-dihydro-9-dimethylallylphenazine 1-carboxylate
show the reaction diagram
-
dimethylallyl diphosphate + L-tyrosine = diphosphate + 4-O-dimethylallyl-L-tyrosine
show the reaction diagram
-
geranyl diphosphate + flaviolin = 3-linalylflaviolin + diphosphate
show the reaction diagram
-
geranyl diphosphate + 2-O-methyl-3-methylflaviolin = diphosphate + (E)-7-((3,7-dimethylocta-2,6-dien-1-yl)oxy)-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione + 6-prenyl-2-methoxy-3-methylflaviolin
show the reaction diagram
-
geranyl diphosphate + 2-O-methyl-3-methylflaviolin = diphosphate + 7-[[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy]-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione
show the reaction diagram
-
tuberculosinyl diphosphate + adenosine = 1-tuberculosinyladenosine + diphosphate
show the reaction diagram
-
all-trans-pentaprenyl diphosphate + sn-glycerol 1-phosphate = sn-3-O-(farnesylgeranyl)glycerol 1-phosphate + diphosphate
show the reaction diagram
-
all-trans-pentaprenyl diphosphate + sn-3-O-(farnesylgeranyl)glycerol 1-phosphate = 2,3-bis-O-(geranylfarnesyl)-sn-glycerol 1-phosphate + diphosphate
show the reaction diagram
-
dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate
show the reaction diagram
-
2 dimethylallyl diphosphate + 2 (6aS,11aS)-3,6a,9-trihydroxypterocarpan = 2 diphosphate + (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan
show the reaction diagram
-
geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + 3-(O-geranylgeranyl)-sn-glycerol 1-phosphate
show the reaction diagram
-
geranylgeranyl diphosphate + 3-(O-geranylgeranyl)-sn-glycerol 1-phosphate = diphosphate + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
show the reaction diagram
-
2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate
show the reaction diagram
-
dimethylallyl diphosphate + leachianone G = diphosphate + sophoraflavanone G
show the reaction diagram
-
octaprenyl diphosphate + 1,4-dihydroxy-2-naphthoate = a demethylmenaquinol + diphosphate + CO2
show the reaction diagram
-
dimethylallyl diphosphate + L-tryptophan = diphosphate + 7-(3-methylbut-2-enyl)-L-tryptophan
show the reaction diagram
-
geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate
show the reaction diagram
-
all-trans-geranylfarnesyl diphosphate + 6 isopentenyl diphosphate = 6 diphosphate + hexatrans,tetracis-undecaprenyl diphosphate
show the reaction diagram
-
(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate
show the reaction diagram
-
(2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate
show the reaction diagram
-
geranyl diphosphate + 4-hydroxybenzoate = 3-geranyl-4-hydroxybenzoate + diphosphate
show the reaction diagram
-
dimethylallyl diphosphate + L-tryptophan = diphosphate + 5-(3-methylbut-2-enyl)-L-tryptophan
show the reaction diagram
-
geranylfarnesyl diphosphate + 6 isopentenyl diphosphate = 6 diphosphate + tetratrans,hexacis-undecaprenyl diphosphate
show the reaction diagram
-
bacteriochlorophyllide a + phytyl diphosphate = bacteriochlorophyll a + diphosphate
show the reaction diagram
-
dimethylallyl diphosphate + L-tryptophan = diphosphate + 1-(2-methylbut-3-en-2-yl)-L-tryptophan
show the reaction diagram
-
adenosylcobinamide phosphate + GTP = adenosylcobinamide-GDP + diphosphate
show the reaction diagram
-
ATP + (R)-4-phosphopantoate + beta-alanine = AMP + diphosphate + (R)-4'-phosphopantothenate
show the reaction diagram
-
[pyruvate, phosphate dikinase] phosphate + phosphate = [pyruvate, phosphate dikinase] + diphosphate
show the reaction diagram
-
NTP + 7 dNTP = N(pdN)7 + 7 diphosphate
show the reaction diagram
-
CTP + N5-phospho-L-glutamine = diphosphate + N5-(cytidine 5'-diphosphoramidyl)-L-glutamine
show the reaction diagram
-
2-hydroxyethylphosphonate + CTP = cytidine 5'-[[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate] + diphosphate
show the reaction diagram
-
phosphoenolpyruvate + GTP = enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate
show the reaction diagram
-
3-phospho-D-glycerate + GTP = 3-(D-glyceryl)-diphospho-5'-guanosine + diphosphate
show the reaction diagram
-
UTP + alpha-D-xylose 1-phosphate = diphosphate + UDP-xylose
show the reaction diagram
-
UTP + alpha-D-galactose 1-phosphate = diphosphate + UDP-alpha-D-galactose
show the reaction diagram
-
CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine
show the reaction diagram
-
CTP + alpha-D-glucose 1-phosphate = diphosphate + CDP-glucose
show the reaction diagram
-
GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose
show the reaction diagram
-
CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate
show the reaction diagram
-
UTP + 1-phospho-alpha-D-glucuronate = diphosphate + UDP-alpha-D-glucuronate
show the reaction diagram
-
GTP + GTP = diphosphate + P1,P4-bis(5'-guanosyl)tetraphosphate
show the reaction diagram
-