Ligand 3-buten-2-one

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Basic Ligand Information

Molecular Structure
Picture of 3-buten-2-one (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H6O
3-buten-2-one
FUSUHKVFWTUUBE-UHFFFAOYSA-N
Synonyms:
1-buten-3-one, but-1-en-3-one, but-3-en-2-one, Methyl vinyl ketone, methylvinylketone, trans-methylvinylketone

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-buten-2-one + NADPH + H+ = butan-2-one + NADP+
show the reaction diagram
-
but-3-en-2-one + NADPH = butan-2-one + NADP+
show the reaction diagram
-
3-buten-2-one + NADPH = 2-butanone + NADP+
show the reaction diagram
-
pyruvate + but-3-en-2-one = hexane-2,5-dione + CO2
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-butene-3-ol + NAD+ = 1-buten-3-one + NADH
show the reaction diagram
-
(3S,6E)-nerolidol + [reduced NADPH-hemoprotein reductase] + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + [oxidized NADPH-hemoprotein reductase] + but-3-en-2-one + 2 H2O
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
74% inhibition at 10 mM
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.167
-
wild-type, pH 7.5, temperature not specified in the publication
156
-
-
29
-
in 50 mM Tris/HCl, pH 7.0, at 25C

KM Value (10 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.035
-
wild-type, pH 7.5, temperature not specified in the publication
1.8
-
apparent value, in 50 mM Tris/HCl, pH 7.0, at 25C

References & Links

Links to other databases for 3-buten-2-one

ChEBI
PubChem
ChEBI
PubChem