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Cell wall polymers of Bacillus sphaericus: activities of enzymes involved in peptidoglycan precursor synthesis during sporulation
1974
Linnett, P.E.; Tipper, D.J.
J. Bacteriol.
120
342-354
Specificity of the uridine-diphosphate-N-acetylmuramyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate synthetase from Escherichia coli
1985
Abo-Ghalia, M.; Michaud, C.; Blanot D.; van Heijenoort, J.
Eur. J. Biochem.
153
81-87
-
Diaminopimelic-adding enzyme (Bacillus cereus)
1971
Mizuno, Y.; Ito, E.
Methods Enzymol.
17B
150-154
Purification and properties of uridine diphosphate N-acetylmuramyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase
1968
Mizuno, Y.; Ito, E.
J. Biol. Chem.
243
2665-2672
Distribution of peptidoglycan synthetase activities between sporangia and forespores in sporulating cells of Bacillus sphaericus
1976
Tipper, D.J.; Linnett, P.E.
J. Bacteriol.
126
213-221
Identification of the mpl gene encoding UDP-N-acetylmuramate:L-alanyl-gamma-glutamyl-meso-diaminopimelate ligase in Escherichia coli and its role in recycling of cell wall peptidoglycan
1996
Mengin-Lecreulx, D.; van Heijenoort, J.; Park, J.T.
J. Bacteriol.
178
5347-5352
Dihydrofolate synthetase and folylpolyglutamate synthetase: direct evidence for intervention of acyl phosphate intermediates
1988
Banerjee, R.V.; Shane, B.; McGuire, J.J.; Coward, J.K.
Biochemistry
27
9062-9070
-
Synthesis of new peptide inhibitors of the meso-diaminopimelate-adding enzyme
1992
le Roux, P.; Auger, G.; van Heijenoort, J.; Blanot, D.
Eur. J. Med. Chem.
27
899-907
Synthesis of inhibitors of the meso-diaminopimelate-adding enzyme from Escherichia coli
1988
Abo-Ghalia, M.; Flegel, M.; Blanot, D.; van Heijenoort, J.
Int. J. Pept. Protein Res.
32
208-222
Replacement of diaminopimelic acid by cystathionine or lanthionine in the peptidoglycan of Escherichia coli
1994
Mengin-Lecreulx, D.; Blanot, D.; van Heijenoort, J.
J. Bacteriol.
176
4321-4327
Over-production, purification and properties of the uridine-diphosphate-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase from Escherichia coli
1990
Michaud, C.; Mengin-Lecreulx, D.; van Heijenoort, J.; Blanot, D.
Eur. J. Biochem.
194
853-861
Cytoplasmic steps of peptidoglycan synthesis in Escherichia coli
1982
Mengin-Lecreulx, D.; Flouret, B.; Van Heijenoort, J.
J. Bacteriol.
151
1109-1117
Levels of cell wall enzymes in endospores and vegetative cells of Bacillus subtilis
1982
Reusch, V.M.; Hale, S.G.; Hurly, B.J.
J. Bacteriol.
152
1147-1153
-
Amino acid racemases and epimerases
1972
Adams, E.
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
6
479-507
Assay and properties of diaminopimelate epimerase from Bacillus megaterium
1969
Withe, P.J.; Lejeune, B.; Work, E.
Biochem. J.
113
589-601
-
Occurence of diaminopimelic epimerase in maize
1982
Tyagi, V.V.S.; Henke, R.R.; Farkas, W.R.
Biochim. Biophys. Acta
719
363-369
-
Species of Bacillus that make a vegetative peptidoglycan containing lysine lack diaminopimelate epimerase but have diaminopimelate dehydrogenase
1985
Bartlett, A.T.M.; White, P.J.
J. Gen. Microbiol.
131
2145-2152
Purification and properties of diaminopimelic acid epimerase from Escherichia coli
1984
Wiseman, J.S.; Nichols, J.S.
J. Biol. Chem.
259
8907-8914
Molecular cloning, characterization, and chromosomal localization of dapF, the Escherichia coli gene for diaminopimelate epimerase
1987
Richaud, C.; Higgins, W.; Mengin-Lecreulx, D.; Stragier, P.
J. Bacteriol.
169
1454-1459
-
Activities and regulation of the enzymes of lysine biosynthesis in a lysine-excreting strain of Bacillus megaterium
1982
Chatterjee, S.P.; White, P.J.
J. Gen. Microbiol.
128
1073-1081
-
Determination of meso-alpha,epsilon-diaminopimelate with meso-alpha,epsilon-diaminopimelate D-dehydrogenase
1980
Misono, H.; Soda, K.
Agric. Biol. Chem.
44
2125-2128
Inhibition of Escherichia coli growth and diaminopimelic acid epimerase by 3-chlorodiaminopimelic acid
1988
Baumann, R.J.; Bohme, E.H.; Wiseman, J.S.; Vaal, M.; Nichols, J.S.
Antimicrob. Agents Chemother.
32
1119-1123
Analogs of diaminopimelic acid as inhibitors of meso-diaminopimelate dehydrogenase and LL-diaminopimelate epimerase
1988
Lam, L.K.P.; Arnold, L.D.; Kalantar, T.H.; Kelland, J.G.; Lane-Bell, P.M.; Palcic, M.M.; Pickard, M.A.; Vederas, J.C.
J. Biol. Chem.
263
11814-11819
2-(4-Amino-4-carboxybutyl)aziridine-2-carboxylic acid. A potent irreversible inhibitor of diaminopimelic acid epimerase. Spontaneous formation from alpha-(halomethyl)diaminopimelic acids
1990
Gerhart, F.; Higgins, W.; Tardif, C.; Ducep, J.B.
J. Med. Chem.
33
2157-2162
A high-performance liquid chromatography method for the simultaneous assay of diaminopimelate epimerase and decarboxylase
1989
Weir, A.N.C.; Bucke, C.; Holt, G.; Lilly, M.D.; Bull, A.T.
Anal. Biochem.
180
298-302
-
Synthesis of 3-fluorodiaminopimelic acid isomers as inhibitors of diaminopimelate epimerase: stereocontrolled enzymatic elimination of hydrogen fluoride
1990
Gelb, M.H.; Lin, Y.; Pickard, M.A.; Song, Y.; Vederas, J.C.
J. Am. Chem. Soc.
112
4932-4942
-
Synthesis and testing of heterocyclic analogues of diaminopimelic acid (DAP) as inhibitors of DAP dehydrogenase and DAP epimerase
1994
Abbott, S.D.; Lane-Bell, P.; Sidhu, K.P.S.; Vederas, J.C.
J. Am. Chem. Soc.
116
6513-6520
-
Stereospecific synthesis of phosphonate analogues of diaminopimelic acid (DAP), their interaction with DAP enzymes and antibacterial activity of peptide derivatives
1994
Song, Y.; Niederer, D.; Lane-Bell, P.M.; Lam, L.K.P.; Crawley, S.; Palcic, M.M.; Pickard, M.A.; Pruess, D.L.; Vederas, J.C.
J. Org. Chem.
59
5784-5793
A functionally split pathway for lysine synthesis in Corynebacterium glutamicum
1991
Schrumpf, B.; Schwarzer, A.; Kalinowski, J.; Puhler, A.; Eggeling, L.; Sahm, H.
J. Bacteriol.
173
4510-4516
In vitro metabolism of the stereoisomers of 2,6-diaminopimelic acid by mixed rumen protozoa and bacteria
1996
El-Waziry, A.M.; Onodera, R.
Curr. Microbiol.
33
306-311
Biosynthesis of lysine in plants: the putative role of meso-diaminopimelate dehydrogenase
1994
Chatterjee, S.P.; Singh, B.K.; Gilvarg, C.
Plant Mol. Biol.
26
285-290
Enzymology of bacterial lysine biosynthesis
1998
Scapin, G.; Blanchard, J.S.
Adv. Enzymol. Relat. Areas Mol. Biol.
72
279-324
Diaminopimelic acid decarboxylase in pyridoxin-deficient Escherichia coli
1955
Denman, R.F.; Hoare, D.S.; Work, E.
Biochim. Biophys. Acta
16
442-443
-
Diaminopimelate decarboxylase
1971
Vogel, H.J.; Hirvonen, A.P.
Methods Enzymol.
17B
146-150
-
Diaminopimelate decarboxylase (Escherichia coli)
1971
White, P.J.
Methods Enzymol.
17B
140-145
Control of lysine biosynthesis in Bacillis subtilis: inhibition of diaminopimelate decarboxylase by lysine
1975
Rosner, A.
J. Bacteriol.
121
20-28
A chloroplast-localized diaminopimelate decarboxylase in higher plants
1976
Mazelis, M.N.; Miflin, B.J.; Prati, H.M.
FEBS Lett.
64
197-200
Lysinbiosynthese bei Pseudomonas aeruginosa PAO 1:1. Einfluss von Cetyl-trimethyl-ammoniumbromid auf P. aeruginosa PAO 1 bei der Bestimmung der DAP-Decarboxylaseaktivität
1978
Schroder, D.; Wolfel, L.; Schoeter, A.; Mach, F.
Z. Allg. Mikrobiol.
18
361-364
Lysinbiosynthese bei Pseudomonas aeruginosa PAO 1 II. Erste Untersuchungen der DAP-Decarboxylase Lysin-auxotropher Mutanten von P. aeruginosa PAO 1
1978
Schroeder, D.; Woelfel, L.; Schroeter, A.; Mach, F.
Z. Allg. Mikrobiol.
18
453-456
-
Purification and properties of meso-alpha,epsilon-diaminopimelate decarboxylase from Bacillus sphaericus
1981
Asada, Y.; Tanizawa, K.; Kawabata, Y.; Misuno, H.; Soda, K.
Agric. Biol. Chem.
45
1513-1514
Stereochemistry of meso-'a,e'-diaminopimelate decarboxylase reaction: the first evidence for pyridoxal 5'phosphate dependent decarboxylation with inversion of configuration
1981
Asada, Y.; Tanizawa, K.; Sawada, S.; Suzuki, T.; Misono, H.; Soda, K.
Biochemistry
20
6881-6886
Lysine biosynthesis and utilization during seed development of normal and opaque-2 Zea mays L.
1983
Dierks-Ventling, C.
Planta
157
233-238
-
Activity of diaminopimelic acid decarboxylase in bacteria producing lysine
1983
Sen, S.K.; Chatterjee, M.; Chatterjee, S.P.; Banerjee, A.K.
Acta Biotechnol.
3
217-220
-
Lysine biosynthesis in Methanobacterium thermoautotrophicum is by the diaminopimelic acid pathway
1984
Bakhiet, N.; Forney, F.W.; Stahly, D.P.; Daniels, L.
Curr. Microbiol.
10
195-198
-
Expression in mammalian cells of the diaminopimelic acid decarboxylase of Escherichia coli permits cell growth in lysine-free medium
1985
Jouanneau, J.; Stragier, P.; Bouvier, J.; Patte, J.C.; Yaniv, M.
Eur. J. Biochem.
145
175-178
Stereochemistry of lysine formation by meso-diaminopimelate decarboxylase from wheat germ: use of 1H-13C NMR shift correlation to detect stereospecific deuterium labeling
1985
Kelland, J.C.; Palcic, M.M.; Pickard, M.A.; Vederas, J.C.
Biochemistry
24
3263-3267
Analogs of diaminopimelic acid as inhibitors of meso-diaminopimelate decarboxylase from Bacillus sphaericus and wheat germ
1986
Kelland, J.C.; Arnold, L.D.; Palcic, M.M.; Pickard, M.A.; Vederas, J.C.
J. Biol. Chem.
261
13216-13223
General organization of the genes specifically involved in the diaminopimelate-lysine biosynthetic pathway of Corynebacterium glutamicum
1988
Yeh, P.; Sicard, A.M.; Sinskey, A.J.
Mol. Gen. Genet.
212
105-111
DAP-decarboxylase activity and lysine production by rumen bacteria
1992
Styriak, I.; Timashova-Kalcheva, E.O.; Kmet, V.; Maljuta, S.S.
Arch. Anim. Nutr.
42
71-77
The regulation of diaminopimelate decarboxylase activity in Escherichia coli strain W
1976
White, P.J.
J. Gen. Microbiol.
96
51-62
Cloning and sequence analysis of the meso-diaminopimelate decarboxylase gene from Bacillus methanolicus MGA 3 and comparison to other decarboxylase genes
1993
Mills, D.A.et al.
Appl. Environ. Microbiol.
59
2927-2937
Specificity profiles of the membrane-bound gamma-D-glutamyl-(L)meso-diaminopimelateendopeptidase and LD-carboxypeptidase from Bacillus sphaericus 9602
1977
Arminjon, F.; Guinand, M.; Vacheron, M.J.; Michel, G.
Eur. J. Biochem.
73
557-565
Envelope-bound N-acetylmuramyl-L-alanine amidase of Escherichia coli K 12. Purification and properties of the enzyme
1975
Van Heijenoort, J.; Parquet, C.; Flouret, B.; Van Heijenoort, Y.
Eur. J. Biochem.
58
611-619
Regulation of enzymes of lysine biosynthesis in Corynebacterium glutamicum
1988
Cremer, J.; Treptow, C.; Eggeling, L.; Sahm, H.
J. Gen. Microbiol.
134
3221-3229
-
Regulation of the enzymes of lysine biosynthesis in Bacillus sphaericus NCTC 9602 during vegetative growth
1986
Bartlett, A.T.M.; White, P.J.
J. Gen. Microbiol.
132
3169-3177
-
Cloning and sequencing of the meso-diaminopimelate-D-dehydrogenase (ddh) gene of Corynebacterium glutamicum
1988
Ishino, S.; Mizukami, T.; Yamaguchi, K.; Katsumata, R.; Araki, K.
Agric. Biol. Chem.
52
2903-2909
Nucleotide sequence of the meso-diaminopimelate D-dehydrogenase gene from Corynebacterium glutamicum
1987
Ishino, S.; Mizukami, T.; Yamaguchi, K.; Katsumata, R.; Araki, K.
Nucleic Acids Res.
15
3917
-
Characterization of meso-diaminopimelate dehydrogenase from Corynebacterium glutamicum and its distribution in bacteria
1986
Misono, H.; Ogasawara, M.; Nagasaki, S.
Agric. Biol. Chem.
50
2729-2734
-
Purification and properties of meso-diaminopimelate dehydrogenase from Brevibacterium sp.
1986
Misono, H.; Ogasawara, M.; Nagasaki, S.
Agric. Biol. Chem.
50
1329-1330
-
2,6-Diaminopimelate
1985
White, P.J.
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
8
377-383
-
Involvement of meso-alpha,epsilon-diamino-pimelate D-dehydrogenase in lysine biosynthesis in Corynebacterium glutamicum
1984
Ishino, S.; Yamaguchi, K.; Shirahata, K.; Araki, K.
Agric. Biol. Chem.
48
2257-2260
-
The essential role of diaminopimelate dehydrogenase in the biosynthesis of lysine by Bacillus sphaericus
1983
White, P.J.
J. Gen. Microbiol.
129
739-749
-
meso-alpha,epsilon-Diaminopimelate D-dehydrogenase: sulfhydryl group modification
1981
Misono, H.; Nagasaki, S.; Soda, K.
Agric. Biol. Chem.
45
1455-1460
Properties of meso-alpha,epsilon-diaminopimelate D-dehydrogenase from Bacillus sphaericus
1980
Misono, H.; Soda, K.
J. Biol. Chem.
255
10599-10605
-
Purification and properties of meso-alpha,epsilon-diaminopimelate D-dehydrogenase from Bacillus sphaericus
1980
Misono, H.; Soda, K.
Agric. Biol. Chem.
44
227-229
meso-alpha,epsilon-Diaminopimelate D-dehydrogenase: distribution and the reaction product
1979
Misono, H.; Togawa, H.; Soda, K.
J. Bacteriol.
137
22-27
Occurrence of meso-alpha, epsilon-diaminopimelate dehydrogenase in Bacillus sphaericus
1976
Misono, H.; Togawa, H.; Yamamoto, T.; Soda, K.
Biochem. Biophys. Res. Commun.
72
89-93
Three-dimensional structure of meso-diaminopimelic acid dehydrogenase from Corynebacterium glutamicum
1996
Scapin, G.; Reddy, S.G.; Blanchard, J.S.
Biochemistry
35
13540-13551
Expression, purification, and crystallization of meso-diaminopimelate dehydrogenase from Corynebacterium glutamicum
1996
Reddy, S.G.; Scapin, G.; Blanchard, J.S.
Proteins Struct. Funct. Genet.
25
514-516
Substrate binding and conformational changes of Corynebacterium glutamicum diaminopimelate dehydrogenase revealed by hydrogen/deuterium exchange and electrospray mass spectrometry
1998
Wang, F.; Scapin, G.; Blanchard, J.S.; Angeletti, R.H.
Protein Sci.
7
293-299
Substrate and inhibitor binding sites in Corynebacterium glutamicum diaminopimelate dehydrogenase
1998
Scapin, G.; Cirilli, M.; Reddy, S.G.; Gao, Y.; Vederas, J.C.; Blanchard, J.S.
Biochemistry
37
3278-3285
The three-dimensional structure of the ternary complex of Corynebacterium glutamicum diaminopimelate dehydrogenase-NADPH-L-2-amino-6-methylene-pimelate
2000
Cirilli, M.; Scapin, G.; Sutherland, A.; Vederas, J.C.; Blanchard, J.S.
Protein Sci.
9
2034-2037
The cell wall and cell division gene cluster in the Mra operon of Pseudomonas aeruginosa: Cloning, production, and purification of active enzymes
2001
Azzolina, B.A.; Yuan, X.; Anderson, M.S.; El-Sherbeini, M.
Protein Expr. Purif.
21
393-400
Crystallization of diaminopimelate decarboxylase from Escherichia coli, a stereospecific D-amino-acid decarboxylase
2002
Momany, C.; Levdikov, V.; Blagova, L.; Crews, K.
Acta Crystallogr. Sect. D
58
549-552
Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments
2001
Dementin, S.; Bouhss, A.; Auger, G.; Parquet, C.; Mengin-Lecreulx, D.; Dideberg, O.; van Heijenoort, J.; Blanot, D.
Eur. J. Biochem.
268
5800-5807
-
Identification of active site cysteine residues that function as general bases: diaminopimelate epimerase
2000
Koo, C.W.; Sutherland, A.; Vederas, J.C.; Blanchard, J.S.
J. Am. Chem. Soc.
122
6122-6123
Crystal structure of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-diaminopimelate ligase from Escherichia coli
2001
Gordon, E.; Flouret, B.; Chantalat, L.; van Heijenoort, J.; Mengin-Lecreulx, D.; Dideberg, O.
J. Biol. Chem.
276
10999-11006
Crystal structure of Mycobacterium tuberculosis diaminopimelate decarboxylase, an essential enzyme in bacterial lysine biosynthesis
2003
Gokulan, K.; Rupp, B.; Pavelka, M.S., Jr.; Jacobs, W.R., Jr.; Sacchettini, J.C.
J. Biol. Chem.
278
18588-18596
Molecular cloning and DNA sequencing of the Staphylococcus aureus UDP-N-acetylmuramyl tripeptide synthetase (murE) gene, essential for the optimal expression of methicillin resistance
1998
Ludovice, A.M.; Wu, S.W.; de Lencastre, H.
Microb. Drug Resist.
4
85-90
Cocrystal structures of diaminopimelate decarboxylase: mechanism, evolution, and inhibition of an antibiotic resistance accessory factor
2002
Ray, S.S.; Bonanno, J.B.; Rajashankar, K.R.; Pinho, M.G.; He, G.; De Lencastre, H.; Tomasz, A.; Burley, S.K.
Structure
10
1499-1508
Use of a codon alteration strategy in a novel approach to cloning the Mycobacterium tuberculosis diaminopimelic acid epimerase
2006
Usha, V.; Dover, L.G.; Roper, D.L.; Lloyd, A.J.; Besra, G.S.
FEMS Microbiol. Lett.
262
39-47
Biochemical characterization and physiological properties of Escherichia coli UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase
2007
Herve, M.; Boniface, A.; Gobec, S.; Bianot, D.; Mengin-Lecreulx, D.
J. Bacteriol.
189
3987-3995
The MurE synthetase from Thermotoga maritima is endowed with an unusual D-lysine adding activity
2006
Boniface, A.; Bouhss, A.; Mengin-Lecreulx, D.; Blanot, D.
J. Biol. Chem.
281
15680-15686
Specificity of L,D-transpeptidases from Gram-positive bacteria producing different peptidoglycan chemotypes
2007
Magnet, S.; Arbeloa, A.; Mainardi, J.L.; Hugonnet, J.E.; Fourgeaud, M.; Dubost, L.; Marie, A.; Delfosse, V.; Mayer, C.; Rice, L.B.; Arthur, M.
J. Biol. Chem.
282
13151-13159
Characterization of Mycobacterium tuberculosis diaminopimelic acid epimerase: paired cysteine residues are crucial for racemization
2008
Usha, V.; Dover, L.G.; Roper, D.L.; Besra, G.S.
FEMS Microbiol. Lett.
280
57-63
The catalytic intermediate stabilized by a "down" active site loop for diaminopimelate decarboxylase from Helicobacter pylori. Enzymatic characterization with crystal structure analysis
2008
Hu, T.; Wu, D.; Chen, J.; Ding, J.; Jiang, H.; Shen, X.
J. Biol. Chem.
283
21284-21293
Pseudomonas aeruginosa MurE amide ligase: enzyme kinetics and peptide inhibitor
2009
Paradis-Bleau, C.; Lloyd, A.; Sanschagrin, F.; Maaroufi, H.; Clarke, T.; Blewett, A.; Dowson, C.; Roper, D.I.; Bugg, T.D.; Levesque, R.C.
Biochem. J.
421
263-272
Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis
2009
Domigan, L.J.; Scally, S.W.; Fogg, M.J.; Hutton, C.A.; Perugini, M.A.; Dobson, R.C.; Muscroft-Taylor, A.C.; Gerrard, J.A.; Devenish, S.R.
Biochim. Biophys. Acta
1794
1510-1516
The three-dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation
2009
Weyand, S.; Kefala, G.; Svergun, D.I.; Weiss, M.S.
J. Struct. Funct. Genomics
10
209-217
Analysis of catalytic determinants of diaminopimelate and ornithine decarboxylases using alternate substrates
2011
Fogle, E.J.; Toney, M.D.
Biochim. Biophys. Acta
1814
1113-1119
Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics
2011
Guzman, J.D.; Wube, A.; Evangelopoulos, D.; Gupta, A.; Huefner, A.; Basavannacharya, C.; Rahman, M.M.; Thomaschitz, C.; Bauer, R.; McHugh, T.D.; Nobeli, I.; Prieto, J.M.; Gibbons, S.; Bucar, F.; Bhakta, S.
J. Antimicrob. Chemother.
66
1766-1772
Evolution and multiplicity of arginine decarboxylases in polyamine biosynthesis and essential role in Bacillus subtilis biofilm formation
2010
Burrell, M.; Hanfrey, C.C.; Murray, E.J.; Stanley-Wall, N.R.; Michael, A.J.
J. Biol. Chem.
285
39224-39238
Comparative modeling of UDP-N-acetylmuramoyl-glycyl-D-glutamate-2,6-diaminopimelate ligase from Mycobacterium leprae and analysis of its binding features through molecular docking studies
2012
Shanmugam, A.; Natarajan, J.
J. Mol. Model.
18
115-125
Improved production of L-lysine by over-expression of meso-diaminopimelate decarboxylase enzyme of Corynebacterium glutamicum in Escherichia coli
2010
Cheraghi, S.; Akbarzade, A.; Farhangi, A.; Chiani, M.; Saffari, Z.; Ghassemi, S.; Rastegari, H.; Mehrabi, M.
Pak. J. Biol. Sci.
13
504-508
Essential residues for the enzyme activity of ATP-dependent MurE ligase from Mycobacterium tuberculosis
2010
Basavannacharya, C.; Moody, P.R.; Munshi, T.; Cronin, N.; Keep, N.H.; Bhakta, S.
Protein Cell
1
1011-1022
-
ATP-dependent MurE ligase in Mycobacterium tuberculosis: Biochemical and structural characterisation
2010
Basavannacharya, C.; Robertson, G.; Munshi, T.; Keep, N.; Bhakta, S.
Tuberculosis
90
16-24
Highly stable meso-diaminopimelate dehydrogenase from an Ureibacillus thermosphaericus strain A1 isolated from a Japanese compost: purification, characterization and sequencing
2011
Akita, H.; Fujino, Y.; Doi, K.; Ohshima, T.
AMB Express
1
43
A novel meso-Diaminopimelate dehydrogenase from Symbiobacterium thermophilum: overexpression, characterization, and potential for D-amino acid synthesis
2012
Gao, X.; Chen, X.; Liu, W.; Feng, J.; Wu, Q.; Hua, L.; Zhu, D.
Appl. Environ. Microbiol.
78
8595-8600
Engineering the meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum by site saturation mutagenesis for D-phenylalanine synthesis
2013
Gao, X.; Huang, F.; Feng, J.; Chen, X.; Zhang, H.; Wang, Z.; Wu, Q.; Zhu, D.
Appl. Environ. Microbiol.
79
5078-5081
Structural insights for the substrate recognition mechanism of LL-diaminopimelate aminotransferase
2011
Watanabe, N.; James, M.N.
Biochim. Biophys. Acta
1814
1528-1533
Creation of a thermostable NADP+-dependent D-amino acid dehydrogenase from Ureibacillus thermosphaericus strain A1 meso-diaminopimelate dehydrogenase by site-directed mutagenesis
2012
Akita, H.; Doi, K.; Kawarabayasi, Y.; Ohshima, T.
Biotechnol. Lett.
34
1693-1699
The structure of LL-diaminopimelate aminotransferase from Chlamydia trachomatis: implications for its broad substrate specificity
2011
Watanabe, N.; Clay, M.D.; van Belkum, M.J.; Fan, C.; Vederas, J.C.; James, M.N.
J. Mol. Biol.
411
649-660
Characterisation of ATP-dependent Mur ligases involved in the biogenesis of cell wall peptidoglycan in Mycobacterium tuberculosis
2013
Munshi, T.; Gupta, A.; Evangelopoulos, D.; Guzman, J.D.; Gibbons, S.; Keep, N.H.; Bhakta, S.
PLoS ONE
8
e60143
Structural insight into the thermostable NADP+-dependent meso-diaminopimelate dehydrogenase from Ureibacillus thermosphaericus
2015
Akita, H.; Seto, T.; Ohshima, T.; Sakuraba, H.
Acta Crystallogr. Sect. D
71
1136-1146
Structural insight into the thermostable NADP+-dependent meso-diaminopimelate dehydrogenase from Ureibacillus thermosphaericus
2015
Akita, H.; Seto, T.; Ohshima, T.; Sakuraba, H.
Acta Crystallogr. Sect. D
71
1136-1146
A newly determined member of the meso-diaminopimelate dehydrogenase family with a broad substrate spectrum
2017
Gao, X.; Zhang, Z.; Zhang, Y.; Li, Y.; Zhu, H.; Wang, S.; Li, C.
Appl. Environ. Microbiol.
83
e00476
Structural and mutational studies on the unusual substrate specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum
2014
Liu, W.; Li, Z.; Huang, C.H.; Guo, R.T.; Zhao, L.; Zhang, D.; Chen, X.; Wu, Q.; Zhu, D.
ChemBioChem
15
217-222
Structural and mutational studies on the unusual substrate specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum
2014
Liu, W.; Li, Z.; Huang, C.H.; Guo, R.T.; Zhao, L.; Zhang, D.; Chen, X.; Wu, Q.; Zhu, D.
ChemBioChem
15
217-222
Structural analysis reveals the substrate-binding mechanism for the expanded substrate specificity of mutant meso-diaminopimelate dehydrogenase
2015
Liu, W.; Guo, R.; Chen, X.; Li, Z.; Gao, X.; Huang, C.; Wu, Q.; Feng, J.; Zhu, D.
ChemBioChem
16
924-929
Structural analysis reveals the substrate-binding mechanism for the expanded substrate specificity of mutant meso-diaminopimelate dehydrogenase
2015
Liu, W.; Guo, R.; Chen, X.; Li, Z.; Gao, X.; Huang, C.; Wu, Q.; Feng, J.; Zhu, D.
ChemBioChem
16
924-929
Effect of residue Y76 on co-enzyme specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum
2015
Zhao, L.; Liu, W.; Chen, X.; Wang, M.; Feng, J.; Wu, Q.; Zhu, D.
Chin. J. Biotechnol.
31
1108-1118
Effect of residue Y76 on co-enzyme specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum
2015
Zhao, L.; Liu, W.; Chen, X.; Wang, M.; Feng, J.; Wu, Q.; Zhu, D.
Chin. J. Biotechnol.
31
1108-1118
Identification of small-molecule inhibitors against meso-2,6-diaminopimelate dehydrogenase from Porphyromonas gingivalis
2015
Stone, V.N.; Parikh, H.I.; El-rami, F.; Ge, X.; Chen, W.; Zhang, Y.; Kellogg, G.E.; Xu, P.
PLoS ONE
10
e0141126
Identification of small-molecule inhibitors against meso-2,6-diaminopimelate dehydrogenase from Porphyromonas gingivalis
2015
Stone, V.N.; Parikh, H.I.; El-rami, F.; Ge, X.; Chen, W.; Zhang, Y.; Kellogg, G.E.; Xu, P.
PLoS ONE
10
e0141126
Unusual substrate specificity of the peptidoglycan MurE ligase from Erysipelothrix rhusiopathiae
2016
Patin, D.; Turk, S.; Barreteau, H.; Mainardi, J.L.; Arthur, M.; Gobec, S.; Mengin-Lecreulx, D.; Blanot, D.
Biochimie
121
209-218
Unusual substrate specificity of the peptidoglycan MurE ligase from Erysipelothrix rhusiopathiae
2016
Patin, D.; Turk, S.; Barreteau, H.; Mainardi, J.L.; Arthur, M.; Gobec, S.; Mengin-Lecreulx, D.; Blanot, D.
Biochimie
121
209-218
Structural basis for substrate specificity of meso-diaminopimelic acid decarboxylase from Corynebacterium glutamicum
2018
Son, H.F.; Kim, K.J.
Biochem. Biophys. Res. Commun.
495
1815-1821
Structural basis for substrate specificity of meso-diaminopimelic acid decarboxylase from Corynebacterium glutamicum
2018
Son, H.F.; Kim, K.J.
Biochem. Biophys. Res. Commun.
495
1815-1821
An optimized coupled assay for quantifying diaminopimelate decarboxylase activity
2015
Peverelli, M.G.; Perugini, M.A.
Biochimie
115
78-85
An optimized coupled assay for quantifying diaminopimelate decarboxylase activity
2015
Peverelli, M.G.; Perugini, M.A.
Biochimie
115
78-85
Dimerization of bacterial diaminopimelate decarboxylase is essential for catalysis
2016
Peverelli, M.G.; Soares da Costa, T.P.; Kirby, N.; Perugini, M.A.
J. Biol. Chem.
291
9785-9795
Dimerization of bacterial diaminopimelate decarboxylase is essential for catalysis
2016
Peverelli, M.G.; Soares da Costa, T.P.; Kirby, N.; Perugini, M.A.
J. Biol. Chem.
291
9785-9795
Characterization of an NAD(P)+-dependent meso-diaminopimelate dehydrogenase from Thermosyntropha lipolytica
2020
Akita, H.; Nakamichi, Y.; Morita, T.; Matsushika, A.
Biochim. Biophys. Acta
1868
140476
Characterization of an NAD(P)+-dependent meso-diaminopimelate dehydrogenase from Thermosyntropha lipolytica
2020
Akita, H.; Nakamichi, Y.; Morita, T.; Matsushika, A.
Biochim. Biophys. Acta
1868
140476
Essential role of amino acid position 71 in substrate preference by meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum IAM14863
2018
Zhang, Y.; Ma, Q.; Dong, M.; Zhang, X.; Chen, Y.; Gao, X.; Song, Y.
Enzyme Microb. Technol.
111
57-62
Essential role of amino acid position 71 in substrate preference by meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum IAM14863
2018
Zhang, Y.; Ma, Q.; Dong, M.; Zhang, X.; Chen, Y.; Gao, X.; Song, Y.
Enzyme Microb. Technol.
111
57-62
Insight into the highly conserved and differentiated cofactor-binding sites of meso-diaminopimelate dehydrogenase StDAPDH
2019
Gao, X.; Ma, Q.; Chen, M.; Dong, M.; Pu, Z.; Zhang, X.; Song, Y.
J. Chem. Inf. Model.
59
2331-2338
Insight into the highly conserved and differentiated cofactor-binding sites of meso-diaminopimelate dehydrogenase StDAPDH
2019
Gao, X.; Ma, Q.; Chen, M.; Dong, M.; Pu, Z.; Zhang, X.; Song, Y.
J. Chem. Inf. Model.
59
2331-2338
Identification and functional characterization of NAD(P)+ -dependent meso-diaminopimelate dehydrogenase from Numidum massiliense
2020
Akita, H.; Nakamichi, Y.; Morita, T.; Matsushika, A.
MicrobiologyOpen
9
e1059
Identification and functional characterization of NAD(P)+ -dependent meso-diaminopimelate dehydrogenase from Numidum massiliense
2020
Akita, H.; Nakamichi, Y.; Morita, T.; Matsushika, A.
MicrobiologyOpen
9
e1059
Overexpression of thermostable meso-diaminopimelate dehydrogenase to redirect diaminopimelate pathway for increasing L-lysine production in Escherichia coli
2019
Xu, J.Z.; Ruan, H.Z.; Liu, L.M.; Wang, L.P.; Zhang, W.G.
Sci. Rep.
9
2423
Overexpression of thermostable meso-diaminopimelate dehydrogenase to redirect diaminopimelate pathway for increasing L-lysine production in Escherichia coli
2019
Xu, J.Z.; Ruan, H.Z.; Liu, L.M.; Wang, L.P.; Zhang, W.G.
Sci. Rep.
9
2423
Wide-open conformation of UDP-MurNc-tripeptide ligase revealed by the substrate-free structure of MurE from Acinetobacter baumannii
2021
Jung, K.H.; Kim, Y.G.; Kim, C.M.; Ha, H.J.; Lee, C.S.; Lee, J.H.; Park, H.H.
FEBS Lett.
595
275-283
-
Structure based in-silico study on UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase (MurE) from Acinetobacter baumannii as a drug target against nosocomial infections
2019
Amera, G.; Khan, R.; Pathak, A.; Kumar, A.; Singh, A.
Inform. Med. Unlocked
16
100216
Structural and conformational behavior of MurE ligase from Salmonella enterica serovar Typhi at different temperature and pH conditions
2020
Bansal, R.; Haque, M.A.; Hassan, M.I.; Ethayathulla, A.S.; Kaur, P.
Int. J. Biol. Macromol.
150
389-399
Design and synthesis of various 5'-deoxy-5'-(4-substituted-1,2,3-triazol-1-yl)-uridine analogues as inhibitors of Mycobacterium tuberculosis Mur ligases
2020
Hervin, V.; Arora, R.; Rani, J.; Ramchandran, S.; Bajpai, U.; Agrofoglio, L.A.; Roy, V.
Molecules
25
4953
Competing substrates for the bifunctional diaminopimelic acid epimerase/glutamate racemase modulate peptidoglycan synthesis in Chlamydia trachomatis
2020
Singh, R.; Slade, J.A.; Brockett, M.; Mendez, D.; Liechti, G.W.; Maurelli, A.T.
Infect. Immun.
89
e00401-20
Structure-function analyses of two plant meso-diaminopimelate decarboxylase isoforms reveal that active-site gating provides stereochemical control
2019
Crowther, J.M.; Cross, P.J.; Oliver, M.R.; Leeman, M.M.; Bartl, A.J.; Weatherhead, A.W.; North, R.A.; Donovan, K.A.; Griffin, M.D.W.; Suzuki, H.; Hudson, A.O.; Kasanmascheff, M.; Dobson, R.C.J.
J. Biol. Chem.
294
8505-8515
Thermostable D-amino acid decarboxylases derived from Thermotoga maritima diaminopimelate decarboxylase
2021
Marjanovic, A.; Ramirez-Palacios, C.J.; Masman, M.F.; Drenth, J.; Otzen, M.; Marrink, S.J.; Janssen, D.B.
Protein Eng. Des. Sel.
34
gzab016
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