| EC Number |
Recommended Name |
Natural Substrates |
Natural Products |
Reversibility |
|---|
  1.1.1.25 | shikimate dehydrogenase (NADP+) |
more |
the bifunctional enzyme dehydroquinate dehydratase/shikimate dehydrogenase (DQD/SDH cf. EC 4.2.1.10 and EC 1.1.1.25) catalyzes the the conversion of 3-dehydroquinate to shikimate via 3-dehydroshikimate |
? |
- |
? |
  1.1.1.25 | shikimate dehydrogenase (NADP+) |
more |
the bifunctional enzyme dehydroquinate dehydratase/shikimate dehydrogenase (DQD3/SDH cf. EC 4.2.1.10 and EC 1.1.1.25) catalyzes the the conversion of 3-dehydroquinate to shikimate via 3-dehydroshikimate |
? |
- |
? |
  1.1.1.25 | shikimate dehydrogenase (NADP+) |
more |
the bifunctional enzyme dehydroquinate dehydratase/shikimate dehydrogenase (DQD/SDH cf. EC 4.2.1.10 and EC 1.1.1.25) catalyzes the the conversion of 3-dehydroquinate to shikimate via 3-dehydroshikimate |
? |
- |
? |
  1.1.1.86 | ketol-acid reductoisomerase (NADP+) |
more |
the enzyme is involved in biosynthesis of branched chain amino acids valine, isoleucine, and leucine, effects of KARI inhibition effects on other enzymes, such as alcohol dehydrogenase, EC 1.1.1.1, pyruvate dehydrogenase, EC 4.1.1.1, lactate dehydrogenase, EC 1.1.1.27, and alanine aminotransferase, EC 2.6.1.2, overview |
? |
- |
? |
  1.1.1.206 | tropinone reductase I |
tropinone + NADPH + H+ |
reaction of tropinone reductase I, EC 1.1.1.206, tropane alkaloid biosynthesis, overview |
tropine + NADP+ |
leading to formation of tropane alkaloids |
? |
  1.1.1.282 | quinate/shikimate dehydrogenase [NAD(P)+] |
more |
the enzyme preferentially uses quinate as a substrate in vitro like a quinate dehydrogenase, EC 1.1.1.24, with only residual shikimate dehydrogenase, SDH, activity, cf. EC 1.1.1.25 |
? |
- |
? |
  1.1.1.298 | 3-hydroxypropionate dehydrogenase (NADP+) |
more |
the malonyl-CoA reductase, MCR, from Chloroflexus aurantiacus is bifunctional, it forms malonyl-CoA from malonyl-semialdehyde, EC 1.2.1.75, and subsequently catalyzes the formation of 3-hydroxypropionate, EC 1.1.1.298 |
? |
- |
? |
  1.1.1.298 | 3-hydroxypropionate dehydrogenase (NADP+) |
more |
the malonyl-CoA reductase, MCR, from Chloroflexus aurantiacus is bifunctional, it forms malonyl-CoA from malonyl-semialdehyde, EC 1.2.1.75, and subsequently catalyzes the formation of 3-hydroxypropionate, EC 1.1.1.298 |
? |
- |
? |
  1.1.2.3 | L-lactate dehydrogenase (cytochrome) |
(S)-lactate + 2 ferricytochrome c |
replaces activity of EC 1.1.1.27 in limited substrate conditions |
pyruvate + 2 ferrocytochrome c + 2 H+ |
- |
? |
  4.4.1.22 | S-(hydroxymethyl)glutathione synthase |
S-(hydroxymethyl)glutathione |
the enzyme accelerates the spontaneous reaction in which the adduct of formaldehyde and glutathione is formed, i.e. the substrate for EC 1.1.1.284, S-(hydroxymethyl)glutathione dehydrogenase, in the formaldehyde-detoxification pathway |
glutathione + formaldehyde |
- |
? |