Disease on EC 7.1.1.3 - ubiquinol oxidase (H+-transporting)
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Colitis
Epithelial-Derived Reactive Oxygen Species Enable AppBCX-Mediated Aerobic Respiration of Escherichia coli during Intestinal Inflammation.
Infections
A fluorescence-based reporter for monitoring expression of mycobacterial cytochrome bd in response to antibacterials and during infection.
Infections
Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis.
Infections
Cytochrome bd in Mycobacterium tuberculosis: A respiratory chain protein involved in the defense against antibacterials.
Infections
Cytochrome bd Protects Bacteria against Oxidative and Nitrosative Stress: A Potential Target for Next-Generation Antimicrobial Agents.
Infections
Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection.
Infections
Respiratory Heterogeneity Shapes Biofilm Formation and Host Colonization in Uropathogenic Escherichia coli.
Infections
The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB.
Persistent Infection
Changes in energy metabolism of Mycobacterium tuberculosis in mouse lung and under in vitro conditions affecting aerobic respiration.
Trypanosomiasis, African
Three redox states of trypanosoma brucei alternative oxidase identified by infrared spectroscopy and electrochemistry.
Tuberculosis
A fluorescence-based reporter for monitoring expression of mycobacterial cytochrome bd in response to antibacterials and during infection.
Tuberculosis
A Mycobacterium tuberculosis cytochrome bd oxidase mutant is hypersensitive to bedaquiline.
Tuberculosis
Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis.
Tuberculosis
Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc1:aa3 in Mycobacterium tuberculosis.
Tuberculosis
Changes in energy metabolism of Mycobacterium tuberculosis in mouse lung and under in vitro conditions affecting aerobic respiration.
Tuberculosis
Cytochrome bd in Mycobacterium tuberculosis: A respiratory chain protein involved in the defense against antibacterials.
Tuberculosis
Cytochrome bd oxidase and hydrogen peroxide resistance in Mycobacterium tuberculosis.
Tuberculosis
Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis.
Tuberculosis
Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection.
Tuberculosis
Features and Functional Importance of Key Residues of the Mycobacterium tuberculosis Cytochrome bd Oxidase.
Tuberculosis
Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase.
Tuberculosis
Identification of 4-Amino-Thieno[2,3-d]Pyrimidines as QcrB Inhibitors in Mycobacterium tuberculosis.
Tuberculosis
Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A Novel Antimycobacterial Class Targeting Mycobacterial Respiration.
Tuberculosis
Structure guided generation of thieno[3,2-d]pyrimidin-4-amine Mycobacterium tuberculosis bd oxidase inhibitors.
Tuberculosis
Susceptibility of Mycobacterium tuberculosis Cytochrome bd Oxidase Mutants to Compounds Targeting the Terminal Respiratory Oxidase, Cytochrome c.
Tuberculosis
The anti-mycobacterial activity of the cytochrome bcc inhibitor Q203 can be enhanced by small-molecule inhibition of cytochrome bd.
Tuberculosis
The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB.
Tuberculosis
The cytochrome bd-type quinol oxidase is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress.
ubiquinol oxidase (h+-transporting) deficiency
Cytochrome bd promotes Escherichia coli biofilm antibiotic tolerance by regulating accumulation of noxious chemicals.
Urinary Tract Infections
Respiratory Heterogeneity Shapes Biofilm Formation and Host Colonization in Uropathogenic Escherichia coli.
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