Reference on EC 6.4.1.1 - pyruvate carboxylase and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ahmad, F.; Ahmad, P.M.; Mendez, A.
Rat liver pyruvate carboxylase. Purification, detection and quantification of apo and holo forms by immuno-blotting and by an enzyme-linked immunosorbent assay
Biochem. J.
236
527-533
1986
Homo sapiens, Mammalia, Rattus norvegicus
Barden, R.E.; Taylor, B.L.; Isohashi, F.; Frey, W.H.; Zander, G.; Lee, J.C.; Utter, M.F.
Structural properties of pyruvate carboxylase from chicken liver and other sources
Proc. Natl. Acad. Sci. USA
72
4308-4312
1975
Bos taurus, Saccharomyces cerevisiae, Gallus gallus, Homo sapiens, Meleagris gallopavo, Pseudomonas citronellolis, Rattus norvegicus, Sus scrofa
MacKay, N.; Rigat, B.; Douglas, C.; Chen, H.S.; Robinson, B.H.
cDNA cloning of human kidney pyruvate carboxylase
Biochem. Biophys. Res. Commun.
29
1009-1014
1994
Homo sapiens
Wexler, I.D.; Du, Y.; Lisgaris, M.V.; Mandal, S.K.; Freytag, S.O.; Yang, B.S.; Liu, T.C.; Kwon, M.; Patel, M.S.; Kerr, D.S.
Primary amino acid sequence and structure of human pyruvate carboxylase
Biochim. Biophys. Acta
1227
46-52
1994
Homo sapiens
Chandler, C.S.; Ballard, F.J.
Distribution and degradation of biotin-containing carboxylases in human cell lines
Biochem. J.
232
385-393
1985
Homo sapiens
Jitrapakdee, S.; Walker, M.E.; Wallace, J.C.
Functional expression, purification, and characterization of recombinant human pyruvate carboxylase
Biochem. Biophys. Res. Commun.
266
512-517
1999
Homo sapiens (P11498), Homo sapiens
Jitrapakdee, S.; Wallace, J.C.
Structure, function and regulation of pyruvate carboxylase
Biochem. J.
340
1-16
1999
Geobacillus stearothermophilus, Saccharomyces cerevisiae, Mammalia, Methanothermobacter thermautotrophicus, Rhizobium etli, Homo sapiens (P11498)
-
Carbone, M.A.; Robinson, B.H.
Expression and characterization of a human pyruvate carboxylase variant by retroviral gene transfer
Biochem. J.
370
275-282
2003
Homo sapiens
Kim, Y.H.; Kim, S.S.
Bcl-2 inhibits tumor necrosis factor-alpha-mediated increase of glycolytic enzyme activities and enhances pyruvate carboxylase activity
Mol. Cells
16
67-73
2003
Homo sapiens
Baez-Saldana, A.; Zendejas-Ruiz, I.; Revilla-Monsalve, C.; Islas-Andrade, S.; Cardenas, A.; Rojas-Ochoa, A.; Vilches, A.; Fernandez-Mejia, C.
Effects of biotin on pyruvate carboxylase, acetyl-CoA carboxylase, propionyl-CoA carboxylase, and markers for glucose and lipid homeostasis in type 2 diabetic patients and nondiabetic subjects
Am. J. Clin. Nutr.
79
238-243
2004
Homo sapiens
Vlasova, T.I.; Stratton, S.L.; Wells, A.M.; Mock, N.I.; Mock, D.M.
Biotin deficiency reduces expression of SLC19A3, a potential biotin transporter, in leukocytes from human blood
J. Nutr.
135
42-47
2005
Homo sapiens
Kim, S.H.; Lee, G.M.
Functional expression of human pyruvate carboxylase for reduced lactic acid formation of Chinese hamster ovary cells (DG44)
Appl. Microbiol. Biotechnol.
76
659-665
2007
Homo sapiens (P11498), Homo sapiens
Jitrapakdee, S.; St Maurice, M.; Rayment, I.; Cleland, W.W.; Wallace, J.C.; Attwood, P.V.
Structure, mechanism and regulation of pyruvate carboxylase
Biochem. J.
413
369-387
2008
Aquifex aeolicus, Geobacillus thermodenitrificans, Bos taurus, Saccharomyces cerevisiae, Ogataea angusta, Homo sapiens, Methanobacterium sp., Methanococcus sp., Methanosarcina sp., Staphylococcus aureus, Mus musculus, Komagataella pastoris, Pseudomonas sp., Rattus norvegicus, Rhizobium etli
Wang, D.; Yang, H.; De Braganca, K.C.; Lu, J.; Yu Shih, L.; Briones, P.; Lang, T.; De Vivo, D.C.
The molecular basis of pyruvate carboxylase deficiency: mosaicism correlates with prolonged survival
Mol. Genet. Metab.
95
31-38
2008
Homo sapiens
Xiang, S.; Tong, L.
Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction
Nat. Struct. Mol. Biol.
15
295-302
2008
Staphylococcus aureus (A0A0H3JRU9), Staphylococcus aureus, Homo sapiens (P11498), Homo sapiens
Monnot, S.; Serre, V.; Chadefaux-Vekemans, B.; Aupetit, J.; Romano, S.; De Lonlay, P.; Rival, J.M.; Munnich, A.; Steffann, J.; Bonnefont, J.P.
Structural insights on pathogenic effects of novel mutations causing pyruvate carboxylase deficiency
Hum. Mutat.
30
734-740
2009
Homo sapiens
Fan, T.W.; Lane, A.N.; Higashi, R.M.; Farag, M.A.; Gao, H.; Bousamra, M.; Miller, D.M.
Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM)
Mol. Cancer
8
41
2009
Homo sapiens
Minet, A.D.; Gaster, M.
Pyruvate carboxylase is expressed in human skeletal muscle
Biochem. Biophys. Res. Commun.
402
196-197
2010
Homo sapiens
Wallace, J.
My favorite pyruvate carboxylase
IUBMB Life
62
535-538
2010
Homo sapiens, Rattus norvegicus
Cheng, T.; Sudderth, J.; Yang, C.; Mullen, A.; Jin, E.; Mates, J.; DeBerardinis, R.
Pyruvate carboxylase is required for glutamine-independent growth of tumor cells
Proc. Natl. Acad. Sci. USA
108
8674-8679
2011
Homo sapiens
Sellers, K.; Fox, M.P.; Bousamra, M.; Slone, S.P.; Higashi, R.M.; Miller, D.M.; Wang, Y.; Yan, J.; Yuneva, M.O.; Deshpande, R.; Lane, A.N.; Fan, T.W.
Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation
J. Clin. Invest.
125
687-698
2015
Homo sapiens (P11498), Homo sapiens
