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Information on EC 6.3.4.6 - urea carboxylase

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EC Tree
     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.6 urea carboxylase
IUBMB Comments
A biotinyl-protein. The yeast enzyme (but not that from green algae) also catalyses the reaction of EC 3.5.1.54 allophanate hydrolase, thus bringing about the hydrolysis of urea to CO2 and NH3. Previously also listed as EC 3.5.1.45. The enzyme from the prokaryotic bacterium Oleomonas sagaranensis can also use acetamide and formamide as substrates .
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
urea amidolyase, dur1,2, urea amido-lyase, atp-urea amidolyase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + urea + HCO3- = ADP + phosphate + urea-1-carboxylate
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PATHWAY SOURCE
PATHWAYS
BRENDA
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