Reference on EC 6.3.4.13 - phosphoribosylamine-glycine ligase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ebbole, D.J.; Zalkin, H.
Cloning and characterization of a 12-gene cluster from Bacillus subtilis encoding nine enzymes for de novo purine nucleotide synthesis
J. Biol. Chem.
262
8274-8287
1987
Bacillus subtilis
Schrimsher, J.L.; Schendel, F.J.; Stubbe, J.
Isolation of a multifunctional protein with aminoimidazole ribonucleotide synthetase, glycinamide ribonucleotide synthetase, and glycinamide ribonucleotide transformylase activities: characterization of aminoimidazole ribonucleotide synthetase
Biochemistry
25
4356-4365
1986
Gallus gallus
Daubner, S.C.; Young, M.; Sammons, R.D.; Courtney, L.F.; Benkovic, S.J.
Structural and mechanistic studies on the HeLa and chicken liver proteins that catalyze glycinamide ribonucleotide synthesis and formylation and aminoimidazole ribonucleotide synthesis
Biochemistry
25
2951-2957
1986
Gallus gallus, Homo sapiens
Daubner, S.C.; Schrimsher, J.L.; Schendel, F.J.; Young, M.; Henikoff, S.; Patterson, D.; Stubbe, J.; Benkovic, S.J.
A multifunctional protein possessing glycinamide ribonucleotide synthetase, glycinamide ribonucleotide transformylase, and aminoimidazole ribonucleotide synthetase activities in de novo purine biosynthesis
Biochemistry
24
7059-7062
1985
Gallus gallus
Gandhi, N.R.; Westby, C.A.
The synthesis of 5'-phosphoribosylglycinamide in Salmonella typhimurium
Enzymologia
42
185-200
1972
Salmonella enterica subsp. enterica serovar Typhimurium
-
Rowe, P.B.; McCairns, E.; Madsen, G.; Sauer, D.; Elliott, H.
De novo purine synthesis in avian liver. Co-purification of the enzymes and properties of the pathway
J. Biol. Chem.
253
7711-7721
1978
Pigeon
Nierlich, D.P.
Phosphoribosylglycinamide synthetase from Aerobacter aerogenes
Methods Enzymol.
51
179-185
1978
Klebsiella aerogenes
Cheng, Y.S.; Murray, M.; Schendel, F.; Otvos, J.; Wehrli, S.; Stubbe, J.
Chemical characterization of phosphoribosylamine, a substrate for newly discovered trifunctional protein containing glycinamide ribonucleotide synthetase activity
Adv. Enzyme Regul.
26
319-333
1987
Gallus gallus, Drosophila melanogaster, Escherichia coli, Schizosaccharomyces pombe
Wheeler, P.R.
Enzymes for purine synthesis and scavening in pathogenic Mycobacterium leprae
J. Gen. Microbiol.
133
3013-3018
1987
Mycobacterium avium, Mycobacterium tuberculosis variant microti
Gnirke, A.; Barnes, T.S.; Patterson, D.; Schild, D.; Featherstone, T.; Olson, M.V.
Cloning and in vivo expression of the human GART gene using yeast artificial chromosomes
EMBO J.
10
1629-1634
1991
Homo sapiens
Antle, V.D.; Liu, D.; McKellar, B.R.; Caperelli, C.A.; Hua, M.; Vince, R.
Substrate specificity of glycinamide ribonucleotide synthetase from chicken liver
J. Biol. Chem.
271
8192-8195
1996
Gallus gallus
Caperelli, C.A.; Liu, D.
Carbocyclic substrates for de novo purine biosynthesis. Enantiospecific synthesis and enantiospecificity of enzymatic utilization
J. Biol. Chem.
267
9783-9787
1992
Gallus gallus
Shen, Y.; Rudolph, J.M.; Stern, J.R.; Stubbe, J.
Glycinamide ribonucleotide synthetase from Escherichia coli: cloning, overproduction, sequencing, isolation, and characterization
Biochemistry
29
218-227
1990
Escherichia coli
Poch, M.T.; Qin, W.; Caperelli, C.A.
The human trifunctional enzyme of de novo purine biosynthesis: heterologous expression, purification, and preliminary characterization
Protein Expr. Purif.
12
17-24
1998
Homo sapiens
Schnorr, K.M.; Laloue, M.; Hirel, B.
Isolation of cDNAs encoding two purine biosynthetic enzymes of soybean and expression of the corresponding transcripts in roots and root nodules
Plant Mol. Biol.
32
751-757
1996
Glycine max
Kan, J.L.; Jannatipour, M.; Taylor, S.M.; Moran, R.G.
Mouse cDNAs encoding a trifunctional protein of de novo purine biosynthesis and a related single-domain glycinamide ribonucleotide synthetase
Gene
137
195-202
1993
Mus musculus
Liu, D.S.; Caperelli, C.A.
Carbocyclic substrates for de novo purine biosynthesis
J. Biol. Chem.
266
16699-16702
1991
Escherichia coli, eukaryota
Henikoff, S.
The Saccharomyces cerevisiae ADE5,7 protein is homologous to overlapping Drosophila melanogaster Gart polypeptides
J. Mol. Biol.
190
519-528
1986
Saccharomyces cerevisiae
Bera, A.K.; Chen, S.; Smith, J.L.; Zalkin, H.
Temperature-dependent function of the glutamine phosphoribosylpyrophosphate amidotransferase ammonia channel and coupling with glycinamide ribonucleotide synthetase in a hyperthermophile
J. Bacteriol.
182
3734-3739
2000
Aquifex aeolicus
Weaver, T.M.; Wang, W.; Ealick, S.E.
Purification, crystallization and preliminary X-ray diffraction data from selenomethionine glycinamide ribonucleotide synthetase
Acta Crystallogr. Sect. D
55
518-521
1999
Escherichia coli
-
Wang, W.; Kappock, T.J.; Stubbe, J.; Ealick, S.E.
X-ray crystal structure of glycinamide ribonucleotide synthetase from Escherichia coli
Biochemistry
37
15647-15662
1998
Escherichia coli (P15640), Escherichia coli
Kanai, S.; Toh, H.
Identification of new members of the GS ADP-forming family from the de novo purine biosynthesis pathway
J. Mol. Evol.
48
482-492
1999
Synechocystis sp., Arabidopsis thaliana, Archaeoglobus fulgidus, Bacillus subtilis, Saccharomyces cerevisiae, Yarrowia lipolytica, Gallus gallus, Drosophila melanogaster, Drosophila pseudoobscura, Escherichia coli, Haemophilus influenzae, Homo sapiens, Methanothermobacter thermautotrophicus, Methanocaldococcus jannaschii, Mus musculus, Pyrococcus horikoshii, Salmonella enterica subsp. enterica serovar Typhimurium, Schizosaccharomyces pombe, Chironomus tentans, Pyrococcus horikoshii OT-3
Kim, J.; Myong, K.; Shim, W.; Yun, S.; Lee, Y.
Functional characterization of acetylglutamate synthase and phosphoribosylamine-glycine ligase genes in Gibberella zeae
Curr. Genet.
51
99-108
2007
Fusarium graminearum
Ng, A.; Uribe, R.A.; Yieh, L.; Nuckels, R.; Gross, J.M.
Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development
Development
136
2601-2611
2009
Danio rerio
Sampei, G.; Baba, S.; Kanagawa, M.; Yanai, H.; Ishii, T.; Kawai, H.; Fukai, Y.; Ebihara, A.; Nakagawa, N.; Kawai, G.
Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria
J. Biochem.
148
429-438
2010
Aquifex aeolicus (O66949), Aquifex aeolicus, Geobacillus kaustophilus (Q5L3C7), Geobacillus kaustophilus, Thermus thermophilus (Q5SK40), Thermus thermophilus
Stoyanov, A.; Petrova, P.; Lyutskanova, D.; Lahtchev, K.
Structural and functional analysis of PUR2,5 gene encoding bifunctional enzyme of de novo purine biosynthesis in Ogataea (Hansenula) polymorpha CBS 4732(T.)
Microbiol. Res.
169
378-387
2014
Ogataea angusta (G8EWC8)
Liu, X.; Ding, Z.; Liu, Y.; Zhang, J.; Liu, F.; Wang, X.; He, X.; Cui, G.; Wang, D.
Glycinamide ribonucleotide formyl transferase is frequently overexpressed in glioma and critically regulates the proliferation of glioma cells
Pathol. Res. Pract.
210
256-263
2014
Homo sapiens (P22102)
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