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Information on EC 6.3.4.1 - GMP synthase
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Synonyms
gmps, more
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DISEASE 
TITLE OF PUBLICATION
LINK TO PUBMED
Acne Vulgaris
In Vivo Reflectance Confocal Microscopy of Gold Microparticles Deposited in the Skin. A Case Report on Cutaneous Chrysiasis.
Acne Vulgaris
Transfollicular delivery of gold microparticles in healthy skin and acne vulgaris, assessed by in vivo reflectance confocal microscopy and optical coherence tomography.
Acquired Immunodeficiency Syndrome
TRIM21-SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis.
Amebiasis
Gut microbiome communication with bone marrow regulates susceptibility to amebiasis.
Atherosclerosis
Roles of hematopoietic stem and progenitor cells in ischemic cardiovascular disease.
Autoimmune Diseases
Nucleotide biosynthetic enzyme GMP synthase is a TRIM21-controlled relay of p53 stabilization.
Blast Crisis
Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.
Breast Neoplasms
Biomineralized anisotropic gold microplate-macrophage interactions reveal frustrated phagocytosis-like phenomenon: a novel paclitaxel drug delivery vehicle.
Breast Neoplasms
Grand multiparity and reproductive cancer in the Jerusalem Perinatal Study Cohort.
Breast Neoplasms
Identification of potential prognostic biomarkers for node-negative breast tumours by proteomic analysis: a multicentric 2004 national PHRC study.
Breast Neoplasms
The noncoding RNAs SNORD50A and SNORD50B-mediated TRIM21-GMPS interaction promotes the growth of p53 wild-type breast cancers by degrading p53.
Carcinoma
The upregulated expression of RFC4 and GMPS mediated by DNA copy number alteration is associated with the early diagnosis and immune escape of ESCC based on a bioinformatic analysis.
Carcinoma, Hepatocellular
Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.
Cardiomyopathies
Clinical usefulness of gated technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography with phase analysis for the management of patients with isolated ventricular noncompaction.
Cardiovascular Diseases
Bone marrow-derived CMPs and GMPs represent highly functional pro-angiogenic cells: implications for ischemic cardiovascular disease.
Cervical Intraepithelial Neoplasia
Guanosine monophosphate synthase upregulation mediates cervical cancer progression by inhibiting the apoptosis of cervical cancer cells via the Stat3/P53 pathway.
Colitis
Dysregulated hematopoietic stem and progenitor cell activity promotes interleukin-23-driven chronic intestinal inflammation.
Coronary Artery Disease
Normal values of cardiac mechanical synchrony parameters using gated myocardial perfusion single-photon emission computed tomography: Impact of population and study protocol.
Coronary Disease
Application of the R0-R3 formulas using the ECToolbox software to calculate left ventricular ejection fraction in myocardial perfusion SPET and comparison with equilibrium radionuclide ventriculography. Normal cutoff values for a Chinese population.
Heart Diseases
Prognostic value of left ventricular dyssynchrony evaluated by gated myocardial perfusion imaging in patients with chronic kidney disease and normal perfusion defect scores.
Heart Failure
Can LV dyssynchrony as assessed with phase analysis on gated myocardial perfusion SPECT predict response to CRT?
Heart Failure
Clinical impacts of scar reduction on gated myocardial perfusion SPECT after cardiac resynchronization therapy.
Heart Failure
Clinical usefulness of gated technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography with phase analysis for the management of patients with isolated ventricular noncompaction.
Heart Failure
Gated single-photon emission computed tomography myocardial perfusion imaging phase analysis as an imaging biomarker for mortality prediction in heart failure patients undergoing cardiac resynchronization therapy.
Heart Failure
Left ventricular dyssynchrony assessed by two three-dimensional imaging modalities: phase analysis of gated myocardial perfusion SPECT and tri-plane tissue Doppler imaging.
Heart Failure
Phase analysis of gated myocardial perfusion single-photon emission computed tomography compared with tissue Doppler imaging for the assessment of left ventricular dyssynchrony.
Heart Failure
Quantitative Gated SPECT-Derived Phase Analysis on Gated Myocardial Perfusion SPECT Detects Left Ventricular Dyssynchrony and Predicts Response to Cardiac Resynchronization Therapy.
Heart Failure
Real-time three-dimensional echocardiography as a novel approach to quantify left ventricular dyssynchrony: a comparison study with phase analysis of gated myocardial perfusion single photon emission computed tomography.
Heart Failure
Reproducibility of global LV function and dyssynchrony parameters derived from phase analysis of gated myocardial perfusion SPECT: A multicenter comparison with core laboratory setting.
Infections
A Focus Group on Dental Pain Complaints with General Medical Practitioners: Developing a Treatment Algorithm.
Infections
Discovery of Novel GMPS Inhibitors of Candidatus Liberibacter Asiaticus by Structure Based Design and Enzyme Kinetic.
Infections
GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway.
Latent Infection
The Critical Role of Genome Maintenance Proteins in Immune Evasion During Gammaherpesvirus Latency.
Leukemia
Cellular and molecular architecture of hematopoietic stem cells and progenitors in genetic models of bone marrow failure.
Leukemia
Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.
Leukemia, Myeloid, Acute
t(3;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (GUANOSINE 5' MONOPHOSPHATE SYNTHETASE) gene.
Liver Neoplasms
Multi-Omics Data Fusion via a Joint Kernel Learning Model for Cancer Subtype Discovery and Essential Gene Identification.
Liver Neoplasms
Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.
Lung Neoplasms
Multi-Omics Data Fusion via a Joint Kernel Learning Model for Cancer Subtype Discovery and Essential Gene Identification.
Melanoma
Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity.
Melanoma
Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers.
Mouth Neoplasms
An audit to analyse the two-week wait pathway at an oral cancer specialist district general hospital.
Mouth Neoplasms
Conducting oral examinations for cancer in general practice: what are the barriers?
Mouth Neoplasms
Oral Cancer Early Detection--a Pressing Need for Continuing Education in Jordan.
Mouth Neoplasms
Oral Cancer Teaching of Medical Students in the UK: Time for a New Approach?
Mouth Neoplasms
The role of primary healthcare professionals in oral cancer prevention and detection.
Myocardial Infarction
Application of the R0-R3 formulas using the ECToolbox software to calculate left ventricular ejection fraction in myocardial perfusion SPET and comparison with equilibrium radionuclide ventriculography. Normal cutoff values for a Chinese population.
Nasopharyngeal Carcinoma
TRIM21-SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis.
Neoplasm Metastasis
Distinct Classes of Flavonoids and Epigallocatechin Gallate, Polyphenol Affects an Oncogenic Mutant p53 Protein, Cell Growth and Invasion in a TNBC Breast Cancer Cell Line.
Neoplasm Metastasis
The upregulated expression of RFC4 and GMPS mediated by DNA copy number alteration is associated with the early diagnosis and immune escape of ESCC based on a bioinformatic analysis.
Neoplasms
Circulating hematopoietic stem and progenitor cells are myeloid-biased in cancer patients.
Neoplasms
Comparison of the diagnostic yield of medical and dental referrals an oral and maxillofacial 2 weeks rule clinic.
Neoplasms
Glomeruloid microvascular proliferation is superior to intratumoral microvessel density as a prognostic marker in non-small cell lung cancer.
Neoplasms
GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7.
Neoplasms
Grand multiparity and reproductive cancer in the Jerusalem Perinatal Study Cohort.
Neoplasms
Guanosine monophosphate synthase upregulation mediates cervical cancer progression by inhibiting the apoptosis of cervical cancer cells via the Stat3/P53 pathway.
Neoplasms
Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.
Neoplasms
Incorporating Geriatric Medicine Providers into the Care of the Older Adult with Cancer.
Neoplasms
Increased expression of VEGF-receptors (FLT-1, KDR, NRP-1) and thrombospondin-1 is associated with glomeruloid microvascular proliferation, an aggressive angiogenic phenotype, in malignant melanoma.
Neoplasms
Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth.
Neoplasms
Integrated Analysis of an lncRNA-Associated ceRNA Network Reveals Potential Biomarkers for Hepatocellular Carcinoma.
Neoplasms
Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers.
Neoplasms
Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.
Neoplasms
The noncoding RNAs SNORD50A and SNORD50B-mediated TRIM21-GMPS interaction promotes the growth of p53 wild-type breast cancers by degrading p53.
Neoplasms
The upregulated expression of RFC4 and GMPS mediated by DNA copy number alteration is associated with the early diagnosis and immune escape of ESCC based on a bioinformatic analysis.
Neoplasms
Two-week wait false alarms? A prospective investigation of 2WW head and neck cancer referrals.
Neutropenia
Pathway genes and metabolites in thiopurine therapy in Korean children with acute lymphoblastic leukaemia.
Periodontal Diseases
Awareness of the association between periodontal disease and pre-term births among general dentists, general medical practitioners and gynecologists.
Periodontal Diseases
Knowledge, awareness, and practice among gynecologists, medical practitioners and dentists in Madurai regarding association between periodontitis and pregnancy outcomes.
Periodontitis
Knowledge, awareness, and practice among gynecologists, medical practitioners and dentists in Madurai regarding association between periodontitis and pregnancy outcomes.
Prostatic Neoplasms
Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth.
Prostatic Neoplasms
Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers.
Stupor
[Intra-individual comparison of alpha- and beta-TCP ceramics in an animal experiment]
Trypanosomiasis, African
GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway.
Tuberculosis
Biochemical characterization of recombinant guaA-encoded guanosine monophosphate synthetase (EC 6.3.5.2) from Mycobacterium tuberculosis H37Rv strain.
Uterine Cervical Neoplasms
Grand multiparity and reproductive cancer in the Jerusalem Perinatal Study Cohort.
Uterine Neoplasms
Grand multiparity and reproductive cancer in the Jerusalem Perinatal Study Cohort.
Highest Expressing Human Cell Lines
Cell Line LinksPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
metabolism
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Release 2026.1 (March 2026)
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