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Information on EC 6.3.2.B24 - beta-tubulin-glutamate ligase

for references in articles please use BRENDA:EC6.3.2.B24
preliminary BRENDA-supplied EC number
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Word Map
  • 6.3.2.B24
  • tubulins
  • polyglutamylation
  • ligase-like
  • microtubule
  • nucleosome
  • carboxypeptidase
  • cilia
  • phosphinic
  • ccp1
  • acid-based
  • axonemal
  • deglutamylation
  • polyglycylated
  • glycylation
The enzyme appears in viruses and cellular organisms
Reaction Schemes
n
+
[beta-tubulin]-C-terminal region L-glutamate
+
n
=
[beta-tubulin]-C-terminal region (gamma-(L-poly-alpha-L-glutamyl))-L-glutamate
+
n
+
n
Synonyms
beta-tubulin polyglutamylase, elongating polyglutamylase, TTLL4, TTLL7, TtTtll6Ap, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
n ATP + [beta-tubulin]-C-terminal region L-glutamate + n L-glutamate = [beta-tubulin]-C-terminal region (gamma-(L-poly-alpha-L-glutamyl))-L-glutamate + n ADP + n phosphate
show the reaction diagram
-
-
-
-
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