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Information on EC 6.3.2.46 - fumarate-(S)-2,3-diaminopropanoate ligase

for references in articles please use BRENDA:EC6.3.2.46
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IUBMB Comments
The enzyme, characterized from the bacterium Enterobacter agglomerans, is involved in biosynthesis of dapdiamide tripeptide antibiotics, a family of fumaramoyl- and epoxysuccinamoyl-peptides named for the presence of an L-2,3-diaminopropanoate (DAP) moiety and two amide linkages in their scaffold.
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The enzyme appears in viruses and cellular organisms
Synonyms
DdaG, fumaroyl-2,3-diaminopropionate ligase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + fumarate + L-2,3-diaminopropanoate = AMP + diphosphate + N3-fumaroyl-L-2,3-diaminopropanoate
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