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alpha-tubulin + ADP + phosphate
ATP + detyrosinated alpha-tubulin + L-tyrosine
-
-
-
-
r
ATP + detyrosinated alpha-tubulin + 3-fluoro-Tyr
?
-
tubulin covalently labeled with 3-fluoro-Tyr is competient to polimerize into microtubules
-
-
?
ATP + detyrosinated alpha-tubulin + 3-nitro-L-tyrosine
nitrotyrosinated alpha-tubulin + ADP + phosphate
ATP + detyrosinated alpha-tubulin + iodotyrosine
?
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-DOPA
?
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-hydroxyphenylalanine
?
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-Phe
?
ATP + detyrosinated alpha-tubulin + L-Tyr
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
ATP + detyrosinated alpha-tubulin + tyramine
?
ATP + peptide of detyrosinated alpha tubulin + Tyr
peptide of alpha-tubulin + ADP + phosphate
-
peptides ending like alpha-tubulin with the sequence Gly-Glu-Glu are optimally tyrosinated once a peptide length of 12 residues is reached. The carboxy-terminal tetradecapeptide of detyrosinated alpha-tubulin acts as substrate at 50fold lower efficiency than alphabeta-tubulin
-
-
?
additional information
?
-
ATP + detyrosinated alpha-tubulin + 3-nitro-L-tyrosine
nitrotyrosinated alpha-tubulin + ADP + phosphate
-
-
-
-
ir
ATP + detyrosinated alpha-tubulin + 3-nitro-L-tyrosine
nitrotyrosinated alpha-tubulin + ADP + phosphate
-
-
-
-
ir
ATP + detyrosinated alpha-tubulin + 3-nitro-L-tyrosine
nitrotyrosinated alpha-tubulin + ADP + phosphate
-
35fold lower affinity for nitrotyrosine than for L-tyrosine, nitrotyrosine is incoorporated into the C-terminus
-
?
ATP + detyrosinated alpha-tubulin + L-Phe
?
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-Phe
?
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
?
-
posttranslational addition of Tyr to the carboxyterminal end of detyrosinated alpha-tubulin
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
?
-
posttranslational modification of tubulin with potential significance for the regulation of microtubule assembly or function
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
?
-
activity increases from the embryonic stage to the fourth larval stage L4, decreases from L4 to adult and to aged nematodes with only qualitative alterations in substrate specificity
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
?
-
terminal Tyr is present in about 5% of flagellar alpha-chain from cells in stationary phase and 20% from cells from midlog phase. None is detected in tubulin from cytosol or the subpellicular corset. In contrast to mammalian cells, in which higher state of tyrosinylation characterizes recently assembled or unstable microtubules, terminal Tyr is present only in the most stable polymer, the flagellar double microtubules
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
?
-
posttranslational addition of Tyr to the carboxyterminal end of detyrosinated alpha-tubulin
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
-
tyrosinates Crithidia tubulin but not brain tubulin and is specific for the alpha chain
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
the enzyme plays a vital role in neuronal organization
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
-
the enzyme plays a vital role in neuronal organization
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
-
r
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
-
turkey erythrocyte tubulin
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
-
r
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
tubuline alpha/beta-dimers, no activity with tyrosinate polymerized microtubules in which the tubulin subunits adopt a straighter configuration
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
tubulin tyrosination is a major factor affecting the recruitment of cytoskeleton-associated protein glycine-rich proteins at microtubule plus ends
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + tyramine
?
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + tyramine
?
-
very low activity
-
-
?
additional information
?
-
-
full-length stathmin and tubulin tyrosine ligase compete for binding to tubulin and fail to make a stable tubulin:stathmin:tubulin tyrosine ligase triple complex in solution
-
-
?
additional information
?
-
-
the testis-specific apoptosis related gene TTL.6 (member of the tubulin-tyrosine ligase family) undergoes adaptive evolution in the lineage leading to humans
-
-
?
additional information
?
-
-
microtubule-associated protein 1B interaction with tubulin tyrosine ligase contributes to the control of microtubule tyrosination, interaction between MAP1B and TTL is not regulated by MAP1B phosphorylation, overview
-
-
?
additional information
?
-
-
full-length stathmin and tubulin tyrosine ligase compete for binding to tubulin and fail to make a stable tubulin:stathmin:tubulin tyrosine ligase triple complex in solution
-
-
?
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ATP + detyrosinated alpha-tubulin + L-Tyr
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
additional information
?
-
ATP + detyrosinated alpha-tubulin + L-Tyr
?
-
posttranslational addition of Tyr to the carboxyterminal end of detyrosinated alpha-tubulin
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
?
-
posttranslational modification of tubulin with potential significance for the regulation of microtubule assembly or function
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
?
-
activity increases from the embryonic stage to the fourth larval stage L4, decreases from L4 to adult and to aged nematodes with only qualitative alterations in substrate specificity
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
?
-
terminal Tyr is present in about 5% of flagellar alpha-chain from cells in stationary phase and 20% from cells from midlog phase. None is detected in tubulin from cytosol or the subpellicular corset. In contrast to mammalian cells, in which higher state of tyrosinylation characterizes recently assembled or unstable microtubules, terminal Tyr is present only in the most stable polymer, the flagellar double microtubules
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
?
-
posttranslational addition of Tyr to the carboxyterminal end of detyrosinated alpha-tubulin
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
the enzyme plays a vital role in neuronal organization
-
-
?
ATP + detyrosinated alpha-tubulin + L-Tyr
alpha-tubulin + ADP + phosphate
-
the enzyme plays a vital role in neuronal organization
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
tubuline alpha/beta-dimers, no activity with tyrosinate polymerized microtubules in which the tubulin subunits adopt a straighter configuration
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
tubulin tyrosination is a major factor affecting the recruitment of cytoskeleton-associated protein glycine-rich proteins at microtubule plus ends
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
?
ATP + detyrosinated alpha-tubulin + L-tyrosine
alpha-tubulin + ADP + phosphate
-
-
-
-
?
additional information
?
-
-
the testis-specific apoptosis related gene TTL.6 (member of the tubulin-tyrosine ligase family) undergoes adaptive evolution in the lineage leading to humans
-
-
?
additional information
?
-
-
microtubule-associated protein 1B interaction with tubulin tyrosine ligase contributes to the control of microtubule tyrosination, interaction between MAP1B and TTL is not regulated by MAP1B phosphorylation, overview
-
-
?
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Agammaglobulinemia
[Study on Kveim's test. Positive tests in agammaglobulinemia. Comparison with TTL in presence of Kveim's antigen]
Ameloblastoma
Immunohistochemical demonstration of keratin in ameloblastoma as an indication of tumor differentiation.
Breast Neoplasms
Prediction of non-sentinel lymph node metastasis in early breast cancer by assessing total tumoral load in the sentinel lymph node by molecular assay.
Breast Neoplasms
Role of total tumour load of sentinel lymph node on survival in early breast cancer patients.
Breast Neoplasms
[Comparative study of the lymphocyte surface receptors isolated from the blood and tissue of malignant tumors]
Colorectal Neoplasms
Diagnostic value of thiols, paraoxonase 1, arylesterase and oxidative balance in colorectal cancer in human.
Coma
Tilt-to-length noise coupled by wavefront errors in the interfering beams for the space measurement of gravitational waves.
Confusion
Four transthyretin-like genes of the migratory plant-parasitic nematode Radopholus similis: members of an extensive nematode-specific family.
Dehydration
Microphysical Properties of Tropical Tropopause Layer Cirrus.
Dermatitis, Allergic Contact
[Skin and laboratory tests: comparison of the epicutaneous patch test with the TTL and LIF tests in the diagnosis of medicamentous allergic contact dermatitis]
Glioblastoma
The Prognostic Value of CD133 in Predicting the Relapse and Recurrence Pattern of High-Grade Gliomas on MRI: A Meta-Analysis.
Glioma
The Prognostic Value of CD133 in Predicting the Relapse and Recurrence Pattern of High-Grade Gliomas on MRI: A Meta-Analysis.
Hypersensitivity
[Delayed allergic reaction to amlodipine with a positive lymphocyte transformation test].
Intervertebral Disc Degeneration
MRI analysis of the ISOBAR TTL internal fixation system for the dynamic fixation of intervertebral discs: a comparison with rigid internal fixation.
Intervertebral Disc Degeneration
Short-Term Therapeutic Efficacy of the Isobar TTL Dynamic Internal Fixation System for the Treatment of Lumbar Degenerative Disc Diseases.
Intervertebral Disc Displacement
[Influence of isobar ttl dynamic internal fixation system on adjacent segment degeneration by mri measurement of lumbar nucleus pulposus volume].
Leishmaniasis, Visceral
[Study of cellular immunity in patients with Mediterranean visceral leishmaniasis]
Leukemia
Identification of a novel fusion gene, TTL, fused to ETV6 in acute lymphoblastic leukemia with t(12;13)(p13;q14), and its implication in leukemogenesis.
Lung Neoplasms
Serum total thiol levels and the risk of lung, colorectal, breast and prostate cancer: A prospective case-cohort study.
Lung Neoplasms
[Comparative study of the lymphocyte surface receptors isolated from the blood and tissue of malignant tumors]
Neoplasm Metastasis
Epithelial-to-mesenchymal transition promotes tubulin Detyrosination and Microtentacles that enhance endothelial engagement.
Neoplasm Metastasis
Intraoperative Nomograms, Based on One-Step Nucleic Acid Amplification, for Prediction of Non-sentinel Node Metastasis and Four or More Axillary Node Metastases in Breast Cancer Patients with Sentinel Node Metastasis.
Neoplasm Metastasis
Nomogram including the total tumoral load in the sentinel nodes assessed by one-step nucleic acid amplification as a new factor for predicting nonsentinel lymph node metastasis in breast cancer patients.
Neoplasm Metastasis
One-step nucleic acid amplification assay for intraoperative prediction of advanced axillary lymph node metastases in breast cancer patients with sentinel lymph node metastasis.
Neoplasm Metastasis
Prediction of non-sentinel lymph node metastasis in early breast cancer by assessing total tumoral load in the sentinel lymph node by molecular assay.
Neoplasm Metastasis
Safety and oncological efficacy of bilateral recurrent laryngeal nerve lymph-node dissection after neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma: a propensity-matched analysis.
Neoplasm Metastasis
Total tumor load assessed by one-step nucleic acid amplification assay as an intraoperative predictor for non-sentinel lymph node metastasis in breast cancer.
Neoplasms
Activity of paclitaxel liposome formulations against human ovarian tumor xenografts.
Neoplasms
Blood markers of oxidative stress are strongly associated with poorer prognosis in colorectal cancer patients.
Neoplasms
Epithelial-to-mesenchymal transition promotes tubulin Detyrosination and Microtentacles that enhance endothelial engagement.
Neoplasms
Intraoperative Nomograms, Based on One-Step Nucleic Acid Amplification, for Prediction of Non-sentinel Node Metastasis and Four or More Axillary Node Metastases in Breast Cancer Patients with Sentinel Node Metastasis.
Neoplasms
Low expression of human tubulin tyrosine ligase and suppressed tubulin tyrosination/detyrosination cycle are associated with impaired neuronal differentiation in neuroblastomas with poor prognosis.
Neoplasms
Molecularly determined total tumour load in lymph nodes of stage I-II colon cancer patients correlates with high-risk factors. A multicentre prospective study.
Neoplasms
Nomogram including the total tumoral load in the sentinel nodes assessed by one-step nucleic acid amplification as a new factor for predicting nonsentinel lymph node metastasis in breast cancer patients.
Neoplasms
Nomogram to predict non-sentinel lymph node status using total tumor load determined by one-step nucleic acid amplification: first report from Thailand.
Neoplasms
Normal and prostate cancer cells display distinct molecular profiles of alpha-tubulin posttranslational modifications.
Neoplasms
Parthenolide inhibits tubulin carboxypeptidase activity.
Neoplasms
Role of total tumour load of sentinel lymph node on survival in early breast cancer patients.
Neoplasms
Serum total thiol levels and the risk of lung, colorectal, breast and prostate cancer: A prospective case-cohort study.
Neoplasms
Sesterterpenes as tubulin tyrosine ligase inhibitors. First insight of structure-activity relationships and discovery of new lead.
Neoplasms
Suppression of tubulin tyrosine ligase during tumor growth.
Neoplasms
The Prognostic Value of CD133 in Predicting the Relapse and Recurrence Pattern of High-Grade Gliomas on MRI: A Meta-Analysis.
Neoplasms
The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models.
Neoplasms
The third tubulin pool.
Neoplasms
The use of onestep nucleic acid amplification (OSNA) and tumour related factors in the treatment of axillary breast cancer: A predictive model.
Neoplasms
Three steps to cancer: how phosphorylation of tubulin, tubulin tyrosine ligase and P-glycoprotein may generate and sustain cancer.
Neoplasms
Total tumor load assessed by one-step nucleic acid amplification assay as an intraoperative predictor for non-sentinel lymph node metastasis in breast cancer.
Neoplasms
TTLL12 expression in ovarian cancer correlates with a poor outcome.
Neoplasms
Tubulin detyrosination is a frequent occurrence in breast cancers of poor prognosis.
Neoplasms
Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.
Neoplasms
[Comparative study of the lymphocyte surface receptors isolated from the blood and tissue of malignant tumors]
Neoplasms
[Development of a moving target aiming system using an ultrasound imaging unit]
Neoplasms
[Development of targeting thermosensitive liposomes for tumor treatment].
Neoplastic Cells, Circulating
Epithelial-to-mesenchymal transition promotes tubulin Detyrosination and Microtentacles that enhance endothelial engagement.
Neuroblastoma
Low expression of human tubulin tyrosine ligase and suppressed tubulin tyrosination/detyrosination cycle are associated with impaired neuronal differentiation in neuroblastomas with poor prognosis.
Perinatal Death
A vital role of tubulin-tyrosine-ligase for neuronal organization.
Pheochromocytoma
NF-?B inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Identification of a novel fusion gene, TTL, fused to ETV6 in acute lymphoblastic leukemia with t(12;13)(p13;q14), and its implication in leukemogenesis.
Prostatic Neoplasms
Serum total thiol levels and the risk of lung, colorectal, breast and prostate cancer: A prospective case-cohort study.
Sarcoma
Suppression of tubulin tyrosine ligase during tumor growth.
Spondylolisthesis
Posterior Dynamic Stabilization with Direct Pars Repair via Wiltse Approach for the Treatment of Lumbar Spondylolysis: The Application of a Novel Surgery.
Spondylolysis
Posterior Dynamic Stabilization with Direct Pars Repair via Wiltse Approach for the Treatment of Lumbar Spondylolysis: The Application of a Novel Surgery.
Spondylolysis
[Clinical outcome of ISOBAR TTL dynamic stabilization with pars bone grafting for treatment of lumbar spondylolysis].
Stroke
Association of serum markers of oxidative stress with myocardial infarction and stroke: pooled results from four large European cohort studies.
Varicose Veins
Per-rectal portal scintigraphy as an alternative measure of hepatic venous pressure gradient in chronic liver disease: A preliminary report.
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malfunction
-
mutation of tubulin binding residues largely abolishes the enzyme ability to tyrosinate alpha-tubulin and restrict neurite outgrowth in cultured neurons. The neuronal defects of tubulin tyrosine ligase knockout mice are due to the loss of tubulin tyrosination and not because the enzyme is required to tyrosinate any other substrates. Neurons from TTL-null mice show strong developmental defects, including increased neurite extensions and premature differentiation
additional information
the enzyme's tubulin-contacting residues are well conserved. The alpha-tubulin residues alphaGlu441 and alphaGlu449 anchor the tail by forming hydrogen bonds with residues Arg73, Ala75, Ser76, Ser152, and Val179, and Asn10, Ser12, Arg44, and Pro336 of TTL, respectively. When bound to the enzyme, the polypeptide chain of the alpha-tubulin tail adopts a loop-like conformation between the tail-anchoring residues alphaGlu441 and alphaGlu449. The enzyme's orientation on tubulin heterodimers places its catalytic domain near to alpha-tubulin's C-terminal tail, which binds to the enzyme's active site through two glutamate residues missing from beta-tubulin's C-terminus
physiological function
-
plays a role in cell division, in particular in cell wall deposition
physiological function
-
plays a role in cell division, in particular in cell wall deposition
physiological function
-
the enzyme specifically recognizes the C-terminus of alpha-tubulin adding L-tyrosine to modulate the behavior of microtubules, tyrosinated microtubules are more dynamic than detyrosinated filaments in cells. The enzyme is bound at the interface of tubulin alpha- and beta-subunits and specifically recognizes the tubulin dimer's curved conformation
physiological function
the enzyme specifically recognizes the C-terminus of alpha-tubulin adding L-tyrosine to modulate the behavior of microtubules, tyrosinated microtubules are more dynamic than detyrosinated filaments in cells. The enzyme is bound at the interface of tubulin alpha- and beta-subunits and specifically recognizes the tubulin dimer's curved conformation
physiological function
-
tubulin tyrosine ligase forms a stable complex with tubulin and inhibits tubulin polymerization, it competes in this function with stathmin
physiological function
-
tubulin tyrosine ligase forms a stable complex with tubulin and inhibits tubulin polymerization, it competes in this function with stathmin
physiological function
-
tubulin-tyrosine ligase TTL is required to increase the levels of tyrosinated alpha-tubulin at an axon injury site and plays an important role in injury signaling. Preventing the injury-induced increase in tyrosinated alpha-tubulin by knocking down TTL impairs retrograde organelle transport and delays activation of the pro-regenerative transcription factor c-Jun. In the absence of TTL, axon regeneration is reduced severely
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Wehland, J.; Schrder, H.C.; Weber, K.
Isolation and purification of tubulin tyrosine ligase
Methods Enzymol.
134
170-179
1986
Sus scrofa
brenda
Rudiger, M.; Wehland, J.; Weber, K.
The carboxy-terminal peptide of detyrosinated alpha tubulin provides a minimal system to study the substrate specificity of tubulin-tyrosine ligase
Eur. J. Biochem.
220
309-320
1994
Sus scrofa
brenda
Joniau, M.; Coudijzer, K.; de Cuyper, M.
Reaction of alpha-tubulin with iodotyrosines catalyzed by tubulin:tyrosine ligase: carboxy-terminal labeling of tubulin with [125]monoiodotyrosine
Anal. Biochem.
184
325-329
1990
Sus scrofa
brenda
Chang, S.; Flavin, M.
Tubulin tyrosination in Crithidia: modifying enzymes and modification states of tubulin
Cell Motil. Cytoskeleton
10
400-409
1988
Crithidia fasciculata
brenda
Flavin, M.; Kobayashi, T.; Martensen, T.M.
Tubulin-tyrosine ligase from brain
Methods Cell Biol.
24
257-263
1982
Bos taurus
brenda
Nath, J.; Gallin, J.I.
Ionic requirement and subcellular localization of tubulin tyrosinolation in human polymorphonuclear leucocytes
J. Immunol.
136
628-635
1986
Homo sapiens
brenda
Ersfeld, K.; Wehland, J.; Plessmann, U.; Dodemont, H.; Gerke, V.; Weber, K.
Characterization of the tubulin-tyrosine ligase
J. Cell Biol.
120
725-732
1993
Bos taurus, Sus scrofa
brenda
Wehland, J.; Weber, K.
Tubulin-tyrosine ligase has a binding site on beta-tubulin: a two-domain structure of the enzyme
J. Cell Biol.
104
1059-1067
1987
Sus scrofa
brenda
Argarana, C.E.; Barra, H.S.; Caputto, R.
Release of [14C]tyrosine from tubulinyl-[14C]tyrosine by brain extract separation of a carboxypeptidase from tubulin-tyrosine ligase
Mol. Cell. Biochem.
19
17-21
1978
Rattus norvegicus
brenda
Raybin, D.; Flavin, M.
Enzyme which specifically adds tyrosine to the alpha chain of tubulin
Biochemistry
16
2189-2194
1977
Bos taurus
brenda
Gabius, H.J.; Graupner, G.; Cramer, F.
Activity patterns of aminoacyl-tRNA synthetases, tRNA methylases, arginyltransferase and tubulin:tyrosine ligase during development and ageing of Caenorhabditis elegans
Eur. J. Biochem.
131
231-234
1983
Caenorhabditis elegans
brenda
Rudiger, M.; Weber, K.
Characterization of the post-translational modifications in tubulin from the marginal band of avian erythrocytes
Eur. J. Biochem.
218
107-116
1993
Sus scrofa
brenda
Deans, N.L.; Allison, R.D.; Purich, D.L.
Steady-state kinetic mechanism of bovine brain tubulin:tyrosine ligase
Biochem. J.
286
243-251
1992
Bos taurus
brenda
Monasterio, O.; Nova, E.; Lopez-Brauet, A.; Lagos, R.
Tubulin-tyrosine catalyzes covalent binding of 3-fluoro-tyrosine to tubulin: kinetic and [19F]NMR studies
FEBS Lett.
374
165-168
1995
Gallus gallus
brenda
Coudijzer, K.; Joniau, M.
3 Azido-L-tyrosine as a photoinhibitor of tubulin:tyrosine ligase. Role of thiol groups
FEBS Lett.
268
95-98
1990
Sus scrofa
brenda
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