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Information on EC 6.3.1.2 - glutamine synthetase

for references in articles please use BRENDA:EC6.3.1.2

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IUBMB Comments

Glutamine synthetase, which catalyses the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life. Several types have been described, differing in their oligomeric structures and cofactor requirements.

The enzyme appears in viruses and cellular organisms

Synonyms
glutamine synthetase, gamma-glutamyl transferase, gs-ii, gsiii, taase, glna1, glna2, gln1;2, gln synthetase, gs(1), more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
ammonia assimilation cycle I, ammonia assimilation cycle II, ammonia assimilation cycle III, L-aspartate degradation II (aerobic), L-aspartate degradation III (anaerobic), L-glutamine biosynthesis I
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