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Information on EC 6.2.1.5 - succinate-CoA ligase (ADP-forming) and Organism(s) Pseudomonas aeruginosa

for references in articles please use BRENDA:EC6.2.1.5

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The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The enzyme appears in selected viruses and cellular organisms

Synonyms
sucla2, succd, a-scs, cg11963, scact, adp-forming succinyl-coa synthetase, scs-betaa, a-stk, succinyl-coa synthetase (adp-forming), succinyl-coa ligase (atp-forming), more

SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
A-SCS
-
-
-
-
A-STK
-
-
-
-
SCS-alpha
-
-
-
-
SCS-beta
-
-
-
-
SCS-betaA
-
-
-
-
STK
-
-
-
-
Succinate thiokinase
-
-
-
-
Succinic thiokinase
-
-
-
-
Succinyl coenzyme A synthetase
-
-
-
-
Succinyl coenzyme A synthetase (adenosine diphosphate-forming)
-
-
-
-
Succinyl-CoA synthetase
-
-
-
-
Succinyl-CoA synthetase (ADP-forming)
-
-
-
-
Synthetase, succinyl coenzyme A (adenosine diphosphate-forming)
-
-
-
-
VEG239
-
-
-
-
VEG63
-
-
-
-
Vegetative protein 239
-
-
-
-
Vegetative protein 63
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acid-thiol ligation
-
-
-
-
PATHWAY SOURCE
PATHWAYS
MetaCyc
adipate biosynthesis, adipate degradation, anaerobic energy metabolism (invertebrates, mitochondrial), incomplete reductive TCA cycle, methylaspartate cycle, pyruvate fermentation to acetate V, pyruvate fermentation to acetate VI, reductive TCA cycle I, reductive TCA cycle II, TCA cycle I (prokaryotic), TCA cycle II (plants and fungi), TCA cycle III (animals), TCA cycle V (2-oxoglutarate synthase), TCA cycle VIII (Chlamydia)
SYSTEMATIC NAME
IUBMB Comments
succinate:CoA ligase (ADP-forming)
-
CAS REGISTRY NUMBER
COMMENTARY hide
9080-33-5
-
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY hide
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + succinate + CoA
ADP + phosphate + succinyl-CoA
show the reaction diagram
GTP + succinate + CoA
GDP + phosphate + succinyl-CoA
show the reaction diagram
-
Substrates: enzyme has a low Km value for ADP and for GDP
Products: -
?
top print hide Go to Organism Search
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Highest Expressing Human Cell Lines
Cell Line Links Gene Links
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A8G7CND4_PSEAI
388
0
41539
TrEMBL
-
A0A140SJ79_PSEAI
295
0
30266
TrEMBL
-
A0A431XFA6_PSEAI
388
0
41513
TrEMBL
-
A0A3M5ER22_PSEAI
388
0
41542
TrEMBL
-
A0A8G5U922_PSEAI
388
0
41561
TrEMBL
-
A0A8G7NCH5_PSEAI
295
0
30294
TrEMBL
-
A0A5E5QUL4_PSEAI
295
0
30256
TrEMBL
-
A0A8G7D0Q6_PSEAI
388
0
41571
TrEMBL
-
A0A8G6GL56_PSEAI
295
0
30232
TrEMBL
-
A0A8G4GQZ3_PSEAI
295
0
30238
TrEMBL
-
A0A8G2JTG9_PSEAI
388
0
41559
TrEMBL
-
A0A8G7JTG6_PSEAI
388
0
41559
TrEMBL
-
A0A8G7ND53_PSEAI
388
0
41517
TrEMBL
-
A0A485EQ55_PSEAI
354
0
39052
TrEMBL
-
A0A485ESG7_PSEAI
271
0
27919
TrEMBL
-
A0A367M6K6_PSEAI
246
0
25229
TrEMBL
-
A0A8G6FXF1_PSEAI
295
0
30298
TrEMBL
-
A0A072ZTV5_PSEAI
388
0
41543
TrEMBL
-
A0A8G3TIE8_PSEAI
295
0
30298
TrEMBL
-
A0A8G4NQR0_PSEAI
388
0
41513
TrEMBL
-
A0A8G6YXX4_PSEAI
295
0
30296
TrEMBL
-
A0A8G6YXX9_PSEAI
388
0
41509
TrEMBL
-
A0A4P0V9A2_PSEAI
243
0
24994
TrEMBL
-
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Weitzman, P.D.J.; Jaskowska-Hodges, H.
Pattern of nucleotide utilization in bacterial succinate thiokinases
FEBS Lett.
143
237-240
1982
Klebsiella aerogenes, Alcaligenes faecalis, Salmonella enterica subsp. arizonae, Pimelobacter simplex, Geobacillus stearothermophilus, Priestia megaterium, Brevibacterium linens, Escherichia coli, Kurthia zopfii, Paracoccus denitrificans, More, Pseudomonas aeruginosa, Pseudomonas fluorescens, Pseudomonas stutzeri, Cereibacter sphaeroides, Serratia marcescens, Thermus aquaticus
Manually annotated by BRENDA team
Kavanaugh-Black, A.; Connolly, D.M.; Chugani, S.A.; Chakrabarty, A.M.
Characterization of nucleoside-diphosphate kinase from Pseudomonas aeruginosa: Complex formation with succinyl-CoA synthetase
Proc. Natl. Acad. Sci. USA
91
5883-5887
1994
Pseudomonas aeruginosa
Manually annotated by BRENDA team