Disease on EC 6.1.1.3 - threonine-tRNA ligase
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DISEASE 
TITLE OF PUBLICATION
LINK TO PUBMED
Arthritis
Dermatomyositis with erosive arthropathy: association with the anti-PL-7 antibody.
Brucellosis, Bovine
Exploring the Molecular Basis for Binding of Inhibitors by Threonyl-tRNA Synthetase from Brucella abortus: A Virtual Screening Study.
Dermatomyositis
Dermatomyositis with erosive arthropathy: association with the anti-PL-7 antibody.
Dermatomyositis
Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells.
Dermatomyositis
Polydermatomyositis with anti-PL7 antibody: clinical and laboratory follow-up over a five year period.
Glioma
miR-720 is a key regulator of glioma migration and invasion by controlling TARSL2 expression.
Infections
Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping.
Joint Diseases
Dermatomyositis with erosive arthropathy: association with the anti-PL-7 antibody.
Leishmaniasis, Visceral
Genetic manipulation of Leishmania donovani threonyl tRNA synthetase facilitates its exploration as a potential therapeutic target.
Mitochondrial Diseases
A Human Disease-causing Point Mutation in Mitochondrial Threonyl-tRNA Synthetase Induces Both Structural and Functional Defects.
Mitochondrial Encephalomyopathies
A Human Disease-causing Point Mutation in Mitochondrial Threonyl-tRNA Synthetase Induces Both Structural and Functional Defects.
Myositis
Myositis autoantibody reactivity and catalytic function of threonyl-tRNA synthetase.
Myositis
RENAL, HEPATIC AND IMMUNE FUNCTION INDICES IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY.
Myositis
Secreted Threonyl-tRNA synthetase stimulates endothelial cell migration and angiogenesis.
Neoplasms
Assessing the effects of threonyl-tRNA synthetase on angiogenesis-related responses.
Neoplasms
Contribution of upregulated aminoacyl-tRNA biosynthesis to metabolic dysregulation in gastric cancer.
Neoplasms
Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping.
Ovarian Neoplasms
Threonyl-tRNA synthetase overexpression correlates with angiogenic markers and progression of human ovarian cancer.
Pancreatic Neoplasms
Inhibition of MUC1 biosynthesis via threonyl-tRNA synthetase suppresses pancreatic cancer cell migration.
Polymyositis
Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells.
Polymyositis
Myositis autoantibody reactivity and catalytic function of threonyl-tRNA synthetase.
Polymyositis
Onset of polymyositis with autoantibodies to threonyl-tRNA synthetase during pregnancy.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Borrelidin, a small molecule nitrile-containing macrolide inhibitor of threonyl-tRNA synthetase, is a potent inducer of apoptosis in acute lymphoblastic leukemia.
Starvation
Aminoacyl-tRNA synthetase gene regulation in Bacillus subtilis: induction, repression and growth-rate regulation.
Starvation
Processing of the leader mRNA plays a major role in the induction of thrS expression following threonine starvation in Bacillus subtilis.
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