Information on EC 5.4.99.12 - tRNA pseudouridine38-40 synthase

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EC Tree
     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.12 tRNA pseudouridine38-40 synthase
IUBMB Comments
The uridylate residues at positions 38, 39 and 40 of nearly all tRNAs are isomerized to pseudouridine. TruA specifically modifies uridines at positions 38, 39, and/or 40 in the anticodon stem loop of tRNAs with highly divergent sequences and structures .
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
Deg1, Deg1p, hisT, mPus3p, pseudouridine synthase, pseudouridine synthase 3, pseudouridine synthase I, PSUI, PUS3, Pus3p, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
tRNA uridine38-40 = tRNA pseudouridine38-40
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