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Information on EC 5.4.3.3 - lysine 5,6-aminomutase

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EC Tree
     5 Isomerases
         5.4 Intramolecular transferases
             5.4.3 Transferring amino groups
                5.4.3.3 lysine 5,6-aminomutase
IUBMB Comments
This enzyme is a member of the 'AdoMet radical' (radical SAM) family. It requires pyridoxal 5'-phosphate and adenosylcobalamin for activity. A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
5,6-lam, kamde, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate
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D-lysine = (2R,5S)-2,5-diaminohexanoate
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