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Disease on EC 5.3.99.4 - prostaglandin-I synthase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Aberrant Crypt Foci
Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1.
Abortion, Spontaneous
Nonsteroidal Anti-inflammatory Drug Interaction with Prostacyclin Synthase Protects from Miscarriage.
Acute Kidney Injury
Prostacyclin in endotoxemia-induced acute kidney injury: cyclooxygenase inhibition and renal prostacyclin synthase transgenic mice.
Variable number tandem repeats in the promoter region of prostacyclin synthase gene in choline deficient rats.
Adenocarcinoma
Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors.
TARGETING THE PROSTACYCLIN/PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AXIS IN LUNG CANCER CHEMOPREVENTION.
Adenolymphoma
Parotid incidentaloma identified by positron emission/computed tomography: when to consider diagnoses other than warthin tumor.
Adenoma
Genetic variability in prostaglandin synthesis, fish intake and risk of colorectal polyps.
Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps.
Arthritis
Genetic control of experimental spondylarthropathy.
Microsomal prostaglandin E synthase-1 is a major terminal synthase that is selectively up-regulated during cyclooxygenase-2-dependent prostaglandin E2 production in the rat adjuvant-induced arthritis model.
Atherosclerosis
CD40 ligand-dependent tyrosine nitration of prostacyclin synthase in vivo.
Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients.
Expression of thromboxane synthase, prostacyclin synthase and thromboxane receptor in atherosclerotic lesions: Correlation with plaque composition.
Peroxynitrite and protein tyrosine nitration of prostacyclin synthase.
Prostacyclin and vascular disease.
Prostaglandin E2 synthesis in pigeon aorta: comparison of atherosclerosis-resistant (Show Racer) and atherosclerosis-prone (White Carneau) breeds.
Prostaglandins, platelets, and atherosclerosis.
Radical acetoacetate oxidation by myeloperoxidase, lactoperoxidase, prostaglandin synthetase, and prostacyclin synthetase: implications for atherosclerosis.
Bradycardia
Reversal of bradykinin-induced reflex tachycardia to bradycardia by captopril; evidence for prostacyclin involvement.
Brain Injuries
Beraprost sodium protects against chronic brain injury in aluminum-overload rats.
Breast Neoplasms
Association of CYP8A1 (Prostacyclin I2 synthase) polymorphism rs5602 with breast cancer in Mexican woman.
Common polymorphisms in the prostaglandin pathway genes and their association with breast cancer susceptibility and survival.
CYP2W1, CYP4F11 and CYP8A1 polymorphisms and interaction of CYP2W1 genotypes with risk factors in Mexican women with breast cancer.
Differential effects of tranylcypromine and imidazole on mammary carcinogenesis in rats fed low and high fat diets.
Expression of Prostacyclin-Synthase in Human Breast Cancer: Negative Prognostic Factor and Protection against Cell Death In Vitro.
The JAK2/STAT3 signaling pathway is required for growth of CD44?CD24? stem cell-like breast cancer cells in human tumors.
Carcinogenesis
Chemoprevention of murine lung cancer by gefitinib in combination with prostacyclin synthase overexpression.
Differential effects of tranylcypromine and imidazole on mammary carcinogenesis in rats fed low and high fat diets.
Genetic and epigenetic regulation of the human prostacyclin synthase promoter in lung cancer cell lines.
Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1.
Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy.
Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer.
Pulmonary prostacyclin synthase overexpression chemoprevents tobacco smoke lung carcinogenesis in mice.
Role of prostacyclin synthase in carcinogenesis.
TARGETING THE PROSTACYCLIN/PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AXIS IN LUNG CANCER CHEMOPREVENTION.
Carcinoma
Differential Expression of Prostaglandin I2 Synthase Associated with Arachidonic Acid Pathway in the Oral Squamous Cell Carcinoma.
Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors.
Prostacyclin synthase expression and epigenetic regulation in nonsmall cell lung cancer.
Prostacyclin-synthase expression in head and neck carcinoma patients and its prognostic value in the response to radiotherapy.
Targeted overexpression of prostacyclin synthase inhibits lung tumor progression by recruiting CD4+ T lymphocytes in tumors that express MHC class II.
Carcinoma, Lewis Lung
Targeted overexpression of prostacyclin synthase inhibits lung tumor progression by recruiting CD4+ T lymphocytes in tumors that express MHC class II.
Carcinoma, Non-Small-Cell Lung
Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model.
Prostacyclin synthase expression and epigenetic regulation in nonsmall cell lung cancer.
Carcinoma, Squamous Cell
Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors.
Prostacyclin synthase expression and epigenetic regulation in nonsmall cell lung cancer.
Cardiovascular Diseases
Association of polymorphisms of PTGS2 and CYP8A1 with myocardial infarction.
Dysfunctional recovery of prostacyclin synthase in aspirin-treated vascular cells: implications for prophylaxis of cardiovascular disease.
Genetic polymorphisms of prostacyclin synthase gene and cardiovascular disease.
Human prostacyclin synthase gene and hypertension : the Suita Study.
Prostacyclin analogues: prevention of cardiovascular diseases.
Prostacyclin synthase gene: genetic polymorphisms and prevention of some cardiovascular diseases.
Splicing mutation of the prostacyclin synthase gene in a family associated with hypertension.
Cerebral Hemorrhage
A Promoter polymorphism (rs17222919, -1316T/G) of ALOX5AP is associated with intracerebral hemorrhage in Korean population.
Cerebral Infarction
Association of 5' upstream promoter region of prostacyclin synthase gene variant with cerebral infarction.
Haplotype analysis of the prostacyclin synthase gene and essential hypertension.
Splicing mutation of the prostacyclin synthase gene in a family associated with hypertension.
Total Flavones of Rhododendron simsii Planch Flower Protect against Cerebral Ischemia-Reperfusion Injury via the Mechanism of Cystathionine-?-Lyase-Produced H2S.
Choline Deficiency
Variable number tandem repeats in the promoter region of prostacyclin synthase gene in choline deficient rats.
Colitis, Ulcerative
[Prostacyclin (PGI2) activity in the rectal mucosa of patients with ulcerative colitis (author's transl)]
Colonic Neoplasms
Overexpression of PTGIS Could Predict Liver Metastasis and is Correlated with Poor Prognosis in Colon Cancer Patients.
Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps.
Colorectal Neoplasms
Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy.
Overexpression of PTGIS Could Predict Liver Metastasis and is Correlated with Poor Prognosis in Colon Cancer Patients.
Coronary Artery Disease
CYP8A1 Gene Polymorphisms and Left Main Coronary Artery Disease.
Coronary Vasospasm
Hypoxia-reoxygenation triggers coronary vasospasm in isolated bovine coronary arteries via tyrosine nitration of prostacyclin synthase.
Dengue
[Effects of Dengue virus infection on PGIS expression and PGI2 secretion of human vascular endothelial cells]
Dermatitis, Contact
Coordinated action of microsomal prostaglandin E synthase-1 and prostacyclin synthase on contact hypersensitivity.
Diabetes Mellitus, Type 2
Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients.
The Role of Oxidative Stress in the Pathogenesis of Type 2 Diabetes Mellitus Micro- and Macrovascular Complications:Avenues for a Mechanistic-Based Therapeutic Approach.
Diabetic Neuropathies
Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene.
Diabetic Retinopathy
Tyrosine nitration of prostacyclin synthase is associated with enhanced retinal cell apoptosis in diabetes.
Ductus Arteriosus, Patent
Determination of genetic predisposition to patent ductus arteriosus in preterm infants.
Interactions between PDA-associated polymorphisms and genetic ancestry alter ductus arteriosus gene expression.
Endotoxemia
Prostacyclin in endotoxemia-induced acute kidney injury: cyclooxygenase inhibition and renal prostacyclin synthase transgenic mice.
Erysipelas
Effect of antibiotics on the immune system of animals. III. Experiments in pgis immunized with live and inactivated swine erysipelas vaccines.
Essential Hypertension
Association study between a novel single nucleotide polymorphism of the promoter region of the prostacyclin synthase gene and essential hypertension.
Haplotype analysis of the prostacyclin synthase gene and essential hypertension.
Organization of the human prostacyclin synthase gene and association analysis of a novel CA repeat in essential hypertension.
Polymorphism of the promoter region of prostacyclin synthase gene is not related to essential hypertension.
Familial Primary Pulmonary Hypertension
Association of Rare PTGIS Variants With Susceptibility and Pulmonary Vascular Response in Patients With Idiopathic Pulmonary Arterial Hypertension.
Hepatorenal Syndrome
Immunohistochemical distribution of renal prostaglandin endoperoxide synthase and prostacyclin synthase: diminished endoperoxide synthase in the hepatorenal syndrome.
Hypertension
Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.
Alterations to the vascular vasodepressor prostaglandin system in DOCA-salt hypertensive rats and their enzymatic analysis.
Arthur C. Corcoran Memorial Lecture. The role of eicosanoids in angiotensin-dependent hypertension.
Assessment of the genetic component of hypertension.
Association of Rare PTGIS Variants With Susceptibility and Pulmonary Vascular Response in Patients With Idiopathic Pulmonary Arterial Hypertension.
Comparative Safety and Tolerability of Prostacyclins in Pulmonary Hypertension.
Derivation of an induced pluripotent stem cell line (PUMCHi003-A) from a patient with pulmonary arterial hypertension carrying heterozygous mutation in PTGIS gene.
Functional Prostacyclin Synthase Promoter Polymorphisms: Impact in Pulmonary Arterial Hypertension.
Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension.
Gene transfer therapy by either type 1 or type 2 adeno-associated virus expressing human prostaglandin I2 synthase gene is effective for treatment of pulmonary arterial hypertension.
Generation of an induced pluripotent stem cell line (PUMCHi006-A) derived from a patient with pulmonary arterial hypertension carrying heterozygous c.1339 G > A mutation in PTGIS gene.
Human prostacyclin synthase gene and hypertension : the Suita Study.
Peroxynitrite and protein tyrosine nitration of prostacyclin synthase.
Polymorphism of the promoter region of prostacyclin synthase gene in chronic thromboembolic pulmonary hypertension.
Possible role of prostacyclin synthase in altered prostacyclin generation in DOCA-salt hypertensive rats.
Prostacyclin synthase promoter regulation and familial pulmonary arterial hypertension.
Prostacyclin therapy for pulmonary arterial hypertension.
Relevance of vascular PGI2 synthase to vascular prostacyclin production in Dahl rats susceptible to salt-induced hypertension.
Splicing mutation of the prostacyclin synthase gene in a family associated with hypertension.
Hypertension, Pregnancy-Induced
Control of prostacyclin synthesis in pregnancy-induced hypertension.
Hypertension, Pulmonary
Attenuation of Monocrotaline-Induced Pulmonary Hypertension by Luminal Adeno-Associated Virus Serotype 9 Gene Transfer of Prostacyclin Synthase.
Drug therapy of primary pulmonary hypertension.
Effects of selective and unselective endothelin-receptor antagonists on prostacyclin synthase gene expression in experimental pulmonary hypertension.
Gene transfer of hepatocyte growth factor with prostacyclin synthase in severe pulmonary hypertension of rats.
Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats.
Gene transfer of human prostacyclin synthase into the liver is effective for the treatment of pulmonary hypertension in rats.
Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats.
Polymorphism of the promoter region of prostacyclin synthase gene in chronic thromboembolic pulmonary hypertension.
Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension.
Protein complex formation with heat shock protein 90 in chronic hypoxia-induced pulmonary hypertension in newborn piglets.
Pulmonary prostacyclin synthase overexpression in transgenic mice protects against development of hypoxic pulmonary hypertension.
Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscles attenuates monocrotaline-induced pulmonary hypertension and prolongs survival in rats.
Hypotension
Post-suspension hypotension is attenuated in Sprague-Dawley rats by prostacyclin synthase inhibition.
Prostaglandin synthetase inhibitor treatment and the regulatory role of prostaglandins on organ perfusion.
Infections
Functional polymorphism of the promoter region of the prostacyclin synthase gene and severity of RSV infection in hospitalized children.
Prostaglandin I2 (PGI2) inhibits Brucella abortus internalization in macrophages via PGI2 receptor signaling, and its analogue affects immune response and disease outcome in mice.
Insulin Resistance
A genome-wide association study of gestational diabetes mellitus in Chinese women.
Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation.
Ischemic Stroke
A Promoter polymorphism (rs17222919, -1316T/G) of ALOX5AP is associated with intracerebral hemorrhage in Korean population.
Variants in COX-2, PTGIS, and TBXAS1 Are Associated with Carotid Artery or Intracranial Arterial Stenosis and Neurologic Deterioration in Ischemic Stroke Patients.
Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke.
Liver Cirrhosis
DNA Methylation of PTGIS Enhances Hepatic Stellate Cells Activation and Liver Fibrogenesis.
Lung Diseases
Prostacyclin synthase in smoking-related lung disease.
Lung Neoplasms
Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model.
Chemoprevention of murine lung cancer by gefitinib in combination with prostacyclin synthase overexpression.
Genetic and epigenetic regulation of the human prostacyclin synthase promoter in lung cancer cell lines.
Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer.
Prognostic value of prostaglandin I2 synthase and its correlation with tumor-infiltrating immune cells in lung cancer, ovarian cancer, and gastric cancer.
Prostacyclin prevents murine lung cancer independent of the membrane receptor by activation of peroxisomal proliferator--activated receptor gamma.
Prostacyclin synthase expression and epigenetic regulation in nonsmall cell lung cancer.
Pulmonary prostacyclin synthase overexpression chemoprevents tobacco smoke lung carcinogenesis in mice.
Targeted overexpression of prostacyclin synthase inhibits lung tumor progression by recruiting CD4+ T lymphocytes in tumors that express MHC class II.
TARGETING THE PROSTACYCLIN/PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AXIS IN LUNG CANCER CHEMOPREVENTION.
The future of cyclooxygenase-2 inhibitors and other inhibitors of the eicosanoid signal pathway in the prevention and therapy of lung cancer.
Myocardial Infarction
Association of a novel single nucleotide polymorphism of the prostacyclin synthase gene with myocardial infarction.
Association of polymorphisms of PTGS2 and CYP8A1 with myocardial infarction.
Haplotype Analysis of the CYP8A1 Gene Associated With Myocardial Infarction.
Haplotype analysis of the prostacyclin synthase gene and essential hypertension.
In vivo therapy of myocardial infarction with mesenchymal stem cells modified with prostaglandin I synthase gene improves cardiac performance in mice.
Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke.
[Association of GLu461ALa polymorphism of prostacyclin synthase gene with myocardial infarction in Uigur population]
[Association of polymorphism of the prostacyclin synthase gene with myocardial infarction in Uigur population of Xinjiang]
[Haplotypes analysis of the prostacyclin synthase gene and myocardial infarction in Uigur population]
[Study on the association of cyclooxygenase-2 -765g>C and prostacyclin synthase C1117A polymorphisms and the risk of myocardial infarction in Uigur population of Xinjiang, China]
Neoplasm Metastasis
Combination of Haptoglobin and Osteopontin Could Predict Colorectal Cancer Hepatic Metastasis.
Overexpression of PTGIS Could Predict Liver Metastasis and is Correlated with Poor Prognosis in Colon Cancer Patients.
The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer.
Neoplasms
A Novel Immune-Related Seventeen-Gene Signature for Predicting Early Stage Lung Squamous Cell Carcinoma Prognosis.
Cellular and molecular biology of prostacyclin synthase.
Chemoprevention of murine lung cancer by gefitinib in combination with prostacyclin synthase overexpression.
CIRBP is a novel oncogene in human bladder cancer inducing expression of HIF-1?.
Determination of genetic predisposition to patent ductus arteriosus in preterm infants.
Differential Expression of Prostaglandin I2 Synthase Associated with Arachidonic Acid Pathway in the Oral Squamous Cell Carcinoma.
Elevated expression of the genes encoding TNF-alpha and thromboxane synthase in leucocytes from patients with systemic sclerosis.
Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer.
Evaluation of Epigenetic Drug Targeting of Heterogenous Tumor Cell Fractions Using Potential Biomarkers of Response in Ovarian Cancer.
Expression of Prostacyclin-Synthase in Human Breast Cancer: Negative Prognostic Factor and Protection against Cell Death In Vitro.
Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1.
Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy.
Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors.
In vivo response of the corpus luteum to progesterone treatment of gilts during early gestation.
Isolation and molecular cloning of prostacyclin synthase from bovine endothelial cells.
Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer.
Overexpression of PTGIS Could Predict Liver Metastasis and is Correlated with Poor Prognosis in Colon Cancer Patients.
Prognostic value of prostaglandin I2 synthase and its correlation with tumor-infiltrating immune cells in lung cancer, ovarian cancer, and gastric cancer.
Prostacyclin prevents murine lung cancer independent of the membrane receptor by activation of peroxisomal proliferator--activated receptor gamma.
Prostacyclin-synthase expression in head and neck carcinoma patients and its prognostic value in the response to radiotherapy.
Pulmonary prostacyclin synthase overexpression chemoprevents tobacco smoke lung carcinogenesis in mice.
Role of prostacyclin synthase in carcinogenesis.
Specific components of prostanoid-signaling pathways are present in non-small cell lung cancer cells.
Targeted overexpression of prostacyclin synthase inhibits lung tumor progression by recruiting CD4+ T lymphocytes in tumors that express MHC class II.
The effect of magnesium sulfate on gene expression in maternal microvascular endothelial cells.
The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer.
VEGF expression is augmented by hypoxia?induced PGIS in human fibroblasts.
Neuralgia
Microglial TNF? Induces COX2 and PGI2 Synthase Expression in Spinal Endothelial Cells during Neuropathic Pain.
Obesity
Involvement of prostacyclin synthase in high-fat-diet-induced obesity.
Ovarian Neoplasms
Prognostic value of prostaglandin I2 synthase and its correlation with tumor-infiltrating immune cells in lung cancer, ovarian cancer, and gastric cancer.
Peripheral Nervous System Diseases
Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene.
Pre-Eclampsia
Activities of phospholipase A2, cyclooxygenase, and PGI2 synthase of umbilical venous endothelial cells in preeclamptic women.
Control of prostacyclin synthesis in pregnancy-induced hypertension.
prostaglandin-e synthase deficiency
Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1.
prostaglandin-i synthase deficiency
Drug therapy of primary pulmonary hypertension.
Endothelial prostacyclin protects the kidney from ischemia-reperfusion injury.
Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1.
Involvement of prostacyclin synthase in high-fat-diet-induced obesity.
Pulmonary prostacyclin synthase overexpression in transgenic mice protects against development of hypoxic pulmonary hypertension.
Pulmonary Arterial Hypertension
Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.
Comparative Safety and Tolerability of Prostacyclins in Pulmonary Hypertension.
Derivation of an induced pluripotent stem cell line (PUMCHi003-A) from a patient with pulmonary arterial hypertension carrying heterozygous mutation in PTGIS gene.
Functional Prostacyclin Synthase Promoter Polymorphisms: Impact in Pulmonary Arterial Hypertension.
Gene transfer therapy by either type 1 or type 2 adeno-associated virus expressing human prostaglandin I2 synthase gene is effective for treatment of pulmonary arterial hypertension.
Generation of an induced pluripotent stem cell line (PUMCHi006-A) derived from a patient with pulmonary arterial hypertension carrying heterozygous c.1339 G > A mutation in PTGIS gene.
Polymorphism of the promoter region of prostacyclin synthase gene in chronic thromboembolic pulmonary hypertension.
Prostacyclin synthase promoter regulation and familial pulmonary arterial hypertension.
Prostacyclin therapy for pulmonary arterial hypertension.
Pulmonary Disease, Chronic Obstructive
Beraprost sodium attenuates cigarette smoke extract-induced apoptosis in vascular endothelial cells.
[The expression of prostacyclin in lungs from patients with chronic obstructive pulmonary disease.]
Renal Insufficiency, Chronic
The protective effect of prostacyclin on adriamycin-induced apoptosis in rat renal tubular cells.
Respiratory Tract Infections
Functional polymorphism of the promoter region of the prostacyclin synthase gene and severity of RSV infection in hospitalized children.
Spondylitis
Genetic control of experimental spondylarthropathy.
Spondylitis, Ankylosing
Genetic control of experimental spondylarthropathy.
Squamous Cell Carcinoma of Head and Neck
Differential Expression of Prostaglandin I2 Synthase Associated with Arachidonic Acid Pathway in the Oral Squamous Cell Carcinoma.
Prostacyclin-synthase expression in head and neck carcinoma patients and its prognostic value in the response to radiotherapy.
Stomach Neoplasms
Prognostic value of prostaglandin I2 synthase and its correlation with tumor-infiltrating immune cells in lung cancer, ovarian cancer, and gastric cancer.
Stroke
Cyclooxygenase-1 and bicistronic cyclooxygenase-1/prostacyclin synthase gene transfer protect against ischemic cerebral infarction.
Interactions among Variants in Eicosanoid Genes Increase Risk of Atherothrombotic Stroke in Chinese Populations.
Swine Erysipelas
Effect of antibiotics on the immune system of animals. III. Experiments in pgis immunized with live and inactivated swine erysipelas vaccines.
Tendinopathy
Divergent roles of prostacyclin and PGE2 in human tendinopathy.
Thromboembolism
Effect of thromboxane synthetase inhibitors (OKY-046, OKY-1580) on experimentally induced air embolism in anesthetized dogs.
Thrombosis
CD40 ligand-dependent tyrosine nitration of prostacyclin synthase in vivo.
Effect of a prostaglandin E1 derivative (OP-1206) and acetylsalicylic acid on electrically induced thrombosis in guinea-pig mesenteric artery and its modification by an inhibitor of prostaglandin I2 synthetase, tranylcypromine.
Gene therapy for all aspects of vein-graft disease.
Hypoxia-reoxygenation triggers coronary vasospasm in isolated bovine coronary arteries via tyrosine nitration of prostacyclin synthase.
Inhibition of PGI2 (prostacyclin) synthesis in the arterial wall enhances the formation of white platelet thrombi in vivo.
Role of prostaglandin biochemical pathway in platelet-vessel wall interaction and local thrombosis.
The action of cyclooxygenase and prostacyclin-synthetase inhibitors on platelet-vessel wall interaction.
The inhibition of PGI2 synthetase within the arterial wall by 15-hydroperoxyarachidonic acid enhances local white platelet thrombosis.
The role of prostaglandins in platelet-vessel wall interaction.
[Prostanoids in the treatment of pulmonary arterial hypertension]
Thyroid Cancer, Papillary
Role of COX-2, thromboxane A2 synthase, and prostaglandin I2 synthase in papillary thyroid carcinoma growth.
Trichothiodystrophy Syndromes
Reduced levels of prostaglandin I2 synthase: a distinctive feature of the cancer-free trichothiodystrophy.
Tuberculosis
Structural studies of phosphoglucose isomerase from Mycobacterium tuberculosis H37Rv.
Urinary Bladder Neoplasms
CIRBP is a novel oncogene in human bladder cancer inducing expression of HIF-1?.
Vascular Diseases
Overexpression of prostacyclin synthase inhibits growth of vascular smooth muscle cells.
Peroxynitrite and protein tyrosine nitration of prostacyclin synthase.
Virus Diseases
[Effects of Dengue virus infection on PGIS expression and PGI2 secretion of human vascular endothelial cells]