Information on EC 5.2.1.13 - prolycopene isomerase

additional information

additional information

additional information

additional information

additional information

additional information

Substrates: isozyme substrate specificity in different genotypes, overview. Isozyme CoCRTISO1-Y, which is expressed in yellow petals, converts carotenoids from the cis-to-trans-configuration
Products: -

additional information

additional information

additional information

additional information

additional information

additional information

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview. Isozyme CoCRTISO1-ORb, which is expressed in orange petals, shows no activity with any of the cis-carotenoids tested. Moreover, the CoCRTISO1 genotypes of the F2 progeny obtained by crossing orange and yellow lines link closely to petal color
Products: -

additional information

additional information

additional information

additional information

additional information

additional information

additional information

Substrates: the enzyme can not isomerize the 15-cis double bond of 9,15,9'-tri-cis-zeta-carotene
Products: -

additional information

Substrates: the enzyme can not isomerize the 15-cis double bond of 9,15,9'-tri-cis-zeta-carotene
Products: -

show all columns Go to Natural Substrate Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

LITERATURE

COMMENTARY

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

7,9,7',9'-tetracis-lycopene

all-trans-lycopene

5 entries

additional information

28 entries

7,9,7',9'-tetracis-lycopene

all-trans-lycopene

Substrates: -
Products: -

7,9,7',9'-tetracis-lycopene

all-trans-lycopene

Substrates: -
Products: -

7,9,7',9'-tetracis-lycopene

all-trans-lycopene

Substrates: -
Products: -

7,9,7',9'-tetracis-lycopene

all-trans-lycopene

Substrates: -
Products: -

7,9,7',9'-tetracis-lycopene

all-trans-lycopene

Substrates: -
Products: -

additional information

additional information

additional information

additional information

additional information

additional information

additional information

additional information

additional information

additional information

additional information

additional information

additional information

additional information

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

Substrates: isozyme substrate specificity in different genotypes, overview
Products: -

additional information

additional information

additional information

additional information

additional information

additional information

additional information

show all columns Go to Cofactor Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

COFACTOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

FADH2

requires the reduced cofactor for activity. The enzyme requires anaerobic conditions for activity. Km: 0.00055 mM

FMNH2

can substitute for FADH2, with about 60% loss effectivity

show all columns Go to Activating Compound Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

ACTIVATING COMPOUND

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

additional information

the enzyme requires anaerobic conditions for activity

show all columns Go to pH Optimum Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

pH OPTIMUM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

5.8 - 8

exhibits no pH-dependence in the range pH 5.8-8.0

show all columns Go to Pi Value Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

pI VALUE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

8.24

calculated from sequence

show all columns Go to Organism Search

only manually annotated data include textmining data from AMENDAenzyme occurrence in organism, localization and source tissue with reliability ranks include all textmining data from AMENDAenzyme occurrence in organism, localization and source tissue with reliability ranks + FRENDAco-occurrence of enzyme names and organism names (less precise)

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

cv. Pera

brenda

UniProt

brenda

Oryza sativa

L. var. Nipponbare

B0L964

UniProt

brenda

748913, 749018, 749378

UniProt

brenda

UniProt

brenda

UniProt

brenda

UniProt

brenda

isozyme CoCRTISO1-ORa; gene crtiso

UniProt

brenda

isozyme CoCRTISO1-ORb; gene crtiso

UniProt

brenda

isozyme CoCRTISO1-Y; gene crtiso

UniProt

brenda

isozyme CoCRTISO2; gene crtiso

UniProt

brenda

isozyme CoCRTISO3; gene crtiso

UniProt

brenda

isozyme CoCRTISO4; gene crtiso

UniProt

brenda

712505, 713267, 775767

brenda

var. Periyakulam 1 (PKM1)

UniProt

brenda

show all columns Go to Source Tissue Search

only manually annotated data include textmining data from AMENDAenzyme occurrence in organism, localization and source tissue with reliability ranks

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SOURCE TISSUE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

SOURCE

endosperm

the transcript of Zmcrtiso1 increases throughout endosperm development to day 25 after pollination. Until 30 after pollination the level decreases

brenda

ZEBRA2 is predominantly expressed in mesophyll cells of mature leaves

brenda

panicle

highest expression in the leaf, followed by the pod and the panicle

brenda

petal

brenda

pod

highest expression in the leaf, followed by the pod and the panicle

brenda

additional information

brenda

brenda

brenda

brenda

highest expression in maturing fruit

brenda

fruit

in wild-type fruit, the mRNA levels of CRTISO increase 10fold during the breaker stage of fruit ripening. Expression of CRTISO in fruit of the mutant tangerine(mic) is similar to that in the wild type

brenda

brenda

high expression level, gene CRTISO has the maximal transcription at the stages of colour change (from green to red) and biological ripeness of the fruit

brenda

leaf

brenda

brenda

ZEBRA2 is predominantly expressed in mesophyll cells of mature leaves

brenda

leaf

highest expression among the tissues tested. In plants carrying the Zebra leaf mutation, yellow and green striped leaves appear at the seedling stage and gradually turn pale green towards the end of the tillering stage

brenda

brenda

brenda

additional information

tissue expression analysis of CRTISO gene expression (CsCRTISO, CsCRTISO-L1, CsCRITSOL2, and CsCRITSO-L2B), overview

brenda

additional information

Lycium chinense

A0A140YIA2

expressed in all tissues tested

brenda

additional information

expressed in all tested tissues and organs, with the highest expression in the leaf, followed by the pod and the panicle. Lowest expression in stem and the root

brenda

additional information

analysis of transcriptional pattern of PtCRTISO4 at different cultivation periods

brenda

additional information

analysis of transcriptional pattern of PtCRTISO4 at different cultivation periods

brenda

additional information

18 accessions of tomato cultivars and lines differing in the color of ripe fruit

brenda

show all columns Go to Localization Search

only manually annotated data include textmining data from AMENDAenzyme occurrence in organism, localization and source tissue with reliability ranks

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

LOCALIZATION

ORGANISM

UNIPROT

COMMENTARY

GeneOntology No.

LITERATURE

SOURCE

brenda

brenda

brenda

brenda

brenda

brenda

Highest Expressing Human Cell Lines

Filter by:

Cell Line Links

Gene Links

show all columns Go to General Information Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

malfunction

6 entries

metabolism

4 entries

physiological function

9 entries

additional information

14 entries

malfunction

in the wild type, 7 days after the breaker stage, 75% of total carotenoids in ripe fruit consist of all-trans-lycopene and more than 15% are lycopene precursors (neurosporene, zeta-carotene, phytofluene, and phytoene). In fruit of the mutant tangerine3183, the major carotenoid accumulates is prolycopene, whereas lycopene precursors, mostly in the cis configuration, constitute the rest of the carotenoids

713267

malfunction

Oryza sativa

B0L964

mutation of the ZEBRA2 gene results in the accumulation of all-trans-lycopene precursor, prolycopene (7,9,7',9'-tetracis-lycopene), in dark-grown zebra2 tissues. Light-grown zebra2 mutant exhibits the characteristic zebra phenotype and decreases level of lutein

malfunction

the orange-flowered calendula is a carotenoid isomerase (crtiso) loss-of function mutant that impairs the cis-to-trans conversion of 5-cis-carotenoids. Deletion of Cys-His-His at positions 462-464 in isozyme CoCRTISO1-ORa abolishes enzyme activity completely

malfunction

the orange-flowered calendula is a carotenoid isomerase (crtiso) loss-of function mutant that impairs the cis-to-trans conversion of 5-cis-carotenoids

malfunction

the orange-flowered calendula is a carotenoid isomerase (crtiso) loss-of function mutant that impairs the cis-to-trans conversion of 5-cis-carotenoids. A Gly-to-Glu amino acid substitution at position 450 in CoCRTISO1-ORb abolishes enzyme activity completely

malfunction

downregulation of gene CRTISO results in the low conversion of prolycopene to lycopene. Downregulation of CRTISO expression leading to a phenotype that is intermediate to wild-type and tangerine

metabolism

hypothetic carotenoid pathway in Nannochloropsis, overview. Lycopene is the first branch point in carotenoid biosynthesis pathway

metabolism

regulation of the expression of the carotenoid pathway genes by CRTISO, overview

metabolism

the enzyme is involved in the carotinoid pathway. In plants, carotenoid biosynthesis takes place via the central isoprenoid pathway of plastids. The pathway begins with the formation of phytoene from two molecules of geranylgeranyl diphosphate. Phytoene desaturase (PDS) and carotene desaturase (ZDS) introduce four double bonds into phytoene which then undergoes two symmetric dehydrogenation steps to yield zeta-carotene and lycopene, respectively. A specific enzyme, zeta-carotene isomerase (ZISO), is required for the cis-to-trans conversion to form tri-cis-zeta-carotene and another isomerase, carotenoid cis-trans isomerase (CRTISO), produces all-trans lycopene (commonly known as lycopene) from tetra-cis-lycopene (prolycopene). The all-trans-lycopene gets converted to alpha- or beta-carotene via cyclization of the terminal isoprene groups

metabolism

hypothetic carotenoid pathway in Nannochloropsis, overview. Lycopene is the first branch point in carotenoid biosynthesis pathway

physiological function

Oryza sativa

B0L964

ZEBRA2 is involved in photoprotection in rice

physiological function

isozyme CoCRTISO1 is a key regulator of the accumulation of 5-cis-carotenoids in calendula petals

physiological function

mutation in Mhz5 blocks carotenoid biosynthesis, reduces abscisic acid accumulation, and promotes ethylene production in etiolated seedlings. Mutation or overexpression of Mhz5 alters the expression of ethylene-responsive genes. The Mhz5-mediated abscisic acid pathway acts downstream of ethylene signaling to inhibit root growth

748913

physiological function

mutation leads to moderately increased tiller numbers, semi-dwarfism and leaf variegation. Prolycopene accumulates while all-trans-lycopene is barely detectable in the dark-grown Mit3 mutant seedlings. Content of lutein and beta-carotene and of 2'-5-epi-5-deoxystrigol is significant in the mutants

749018

physiological function

Lycium chinense

A0A140YIA2

overexpression in transgenic tobacco resultsin an increase of total carotenoids in the leaves with betaotene and lutein being the predominants

physiological function

carotenoid isomerase (CRTISO) catalyzing the lycopene formation, is regarded as a key enzyme for carotenogenesis in Phaeodactylum tricornutum, which can accumulate high-level carotenoids under optimal conditions. Isozyme PtCRTISO4 plays an additional regulatory role in terms of carotenoid accumulation

physiological function

the red color of tomato (Solanum lycopersicum) fruit comes from lycopene that is an effective natural antioxidant and is formed by enzyme carotinoid isomerase from prolycopene. Central role of carotenoid isomerase (CRTISO) in the cis to trans isomerization of prolycopene in tomato

physiological function

carotene cis-trans isomerase CRTISO catalyzes cis-trans isomerization of double bonds leading to the formation of all-trans-lycopene, which is the most powerful antioxidant among carotenoids and a substrate for subsequent synthesis of alpha-, beta-carotenes, and xanthophylls. The enzyme plays an important role in the carotenoid metabolism due to the wide variety of carotenoid-mediated pigmentation of the ripe fruit. Effect of the carotenoid content and activity of the carotene cis-trans isomerase CRTISO on tomato fruit colour, e.g. the green-fruited line L-Nesozrevayushchii, the yellow-fruited cv. Viking, the redfruited cv. Malinovyi Silach, and the brown-redfruited line L-176, overview. Quantitative real-time PCR does not reveal any strong correlation between the level of CRTISO gene expression and total carotenoids, which may be explained by a different quantity of metabolites preceding prolycopene

physiological function

additional information

residues Cys-His-His at positions 462-464 in isozymes CoCRTISO1-ORa are important for the enzymatic activity of the CRTISO isozyme

additional information

residues Cys-His-His at positions 462-464 in isozymes CoCRTISO1-ORa are important for the enzymatic activity of the CRTISO isozyme

additional information

residues Cys-His-His at positions 462-464 in isozymes CoCRTISO1-ORa are important for the enzymatic activity of the CRTISO isozyme

additional information

residues Cys-His-His at positions 462-464 in isozymes CoCRTISO1-ORa are important for the enzymatic activity of the CRTISO isozyme

additional information

residues Cys-His-His at positions 462-464 in isozymes CoCRTISO1-ORa are important for the enzymatic activity of the CRTISO isozyme

additional information

residues Cys-His-His at positions 462-464 in isozymes CoCRTISO1-ORa are important for the enzymatic activity of the CRTISO isozyme

additional information

residues Cys-His-His at positions 462-464 in isozymes CoCRTISO1-ORa are important for the enzymatic activity of the CRTISO isozyme

additional information

residue Gly450 in isozyme CoCRTISO1-ORb is important for the enzymatic activity of the CRTISO isozyme

additional information

residue Gly450 in isozyme CoCRTISO1-ORb is important for the enzymatic activity of the CRTISO isozyme

additional information

residue Gly450 in isozyme CoCRTISO1-ORb is important for the enzymatic activity of the CRTISO isozyme

additional information

residue Gly450 in isozyme CoCRTISO1-ORb is important for the enzymatic activity of the CRTISO isozyme

additional information

residue Gly450 in isozyme CoCRTISO1-ORb is important for the enzymatic activity of the CRTISO isozyme

additional information

residue Gly450 in isozyme CoCRTISO1-ORb is important for the enzymatic activity of the CRTISO isozyme

additional information

residue Gly450 in isozyme CoCRTISO1-ORb is important for the enzymatic activity of the CRTISO isozyme

Go to AA Sequence and Transmembrane Helices SearchGo to Localization Prediction

Show AA Sequence and Transmembrane Helices (807 entries)
Please use the AA Sequence and Transmembrane Helices Search for a specific query.

show all columns Go to Molecular Weight Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

MOLECULAR WEIGHT

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

63700

x * 63700, calculated from sequence

show all columns Go to Subunit Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SUBUNIT

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

2 entries

Lycium chinense

A0A140YIA2

x * 664240, calculated from sequence

x * 63700, calculated from sequence

show all columns Go to Protein Variants Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

A412S

site-directed mutagenesis, the mutant shows substrate specificity like the wild-type enzyme

G450E

site-directed mutagenesis, the isozyme CoCRTISO1-ORb mutant is catalytically inactive

I370T

site-directed mutagenesis, the isozyme CoCRTISO1-ORa mutant is catalytically inactive

L581P

site-directed mutagenesis, the isozyme CoCRTISO1-ORa mutant is catalytically inactive

P584L

site-directed mutagenesis, the mutant shows substrate specificity like the wild-type enzyme

S412A

site-directed mutagenesis, the isozyme CoCRTISO1-ORb mutant is catalytically inactive

additional information

4 entries

additional information

the enzyme can complement the Micro-Tom tangerine mutant, that is deficient for the carotenoid isomerase (CRTISO) gene. MT-t plants are successfully complemented with the CsCRTISO, and fruits show a carotenoid profile similar to the control, indicating that the Citrus allele indeed encodes an authentic functional carotenoid isomerase and that the signal peptide is functional in tomato. MT is silenced using an inverted repeat of a fragment from the Citrus CRTISO resulting in a stronger phenotype than MT-t. MT-t and MT silenced for CRTISO presented an overall decrease in transcript accumulation of all genes from the biosynthesis pathway. The expression of the Citrus CRTISO gene is able to restore the biosynthesis of carotenoids with the appropriate regulation in MT-t. The decrease in transcript accumulation in MT-t and MT-CRTISO-suppressed lines reinforces previous suggestions that transcriptional regulation of the carotenoid biosynthesis involves regulatory loops by intermediate products

additional information

compared to the wild-type, all three transgenic lines (T1-T3) of Nannochloropsis oceanica expressing the isozyme PtCRTISO4 exhibit higher levels of total carotenoid and violaxanthin. Quantitative RT-PCR demonstrates that phytoene synthase (NoPSY) rather than z-carotene desaturase (NoZDS) and lycopene beta-cyclase (NoLCYB) exhibits the highest upregulation, suggesting that PtCRTISO4 plays an additional regulatory role in terms of carotenoid accumulation. PtCRTISO4 overexpression increases C18:1n-9 but decreases C16:1n-7, implying that C18:1 may serve as a main feedstock for xanthophyll esterification in Nannochloropsis

additional information

additional information

targeted editing of tomato carotenoid isomerase reveals the role of 5' UTR region in gene expression regulation. Mutations are generated in the 5' UTR and exon 1 of the carotenoid isomerase gene using CRISPR/Cas9 expression via Agrobacterium-mediated transformation of tomato variety Periyakulam 1 (PKM1), transcriptome analysis and fruit phenotype analysis, overview. 5' UTR region deletion leads to a lower expression of CRTISO and to an intermediate phenotype, while the point mutation in exon 1 leads to a knockout loss of function of the CRTISO enzyme. Exon 1 mutants of T1 generation show a heritable tangerine fruit phenotype. Chlorophyll and carotinoid contents are reduced in the mutants compared to wild-type leading to a reduced pigmentation of the fruits

Go to Purification (commentary) Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

PURIFICATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

Go to Cloned (commentary) Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

2 entries

DNA and amino acid sequence determination and analysis, four putative loci in the Citrus sinensis genome, named CsCRTISO, CsCRTISO Like 1, CsCRTISO-Like 2, and CsCRTISO-Like 2B, phylogenetic analysis, recombinant expression of CsCRTISO in Solanum lycopersicum var. Micro-Tom tangerine mutant with functional complementation of the carotinoid isomerase deficiency. In silico expression analysis of CRTISO genes from tomato and Citrus

expression in Escherichia coli

gene CoCRTISO1-ORa, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative real-time PCR analysis

gene CoCRTISO1-ORb, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative real-time PCR analysis

gene CoCRTISO1-Y, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative real-time PCR analysis

gene CoCRTISO2, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative real-time PCR analysis

gene CoCRTISO3, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative real-time PCR analysis

gene CoCRTISO4, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative real-time PCR analysis

gene CRTISO, quantitative real-time PCR enzyme expression analysis in 18 accessions of tomato cultivars and lines differing in the color of ripe fruit

gene CRTISO, quantitative RT-PCR enzyme expression analysis

gene PtCRTISO4, enzyme overexpressing in Nannochloropsis oceanica strain IMET1. Compared to the wild-type, all three transgenic lines (T1-T3) of Nannochloropsis oceanica exhibit higher levels of total carotenoid and violaxanthin. Quantitative RT-PCR demonstrates that phytoene synthase (NoPSY) rather than z-carotene desaturase (NoZDS) and lycopene beta-cyclase (NoLCYB) exhibits the highest upregulation, suggesting that PtCRTISO4 plays an additional regulatory role in terms of carotenoid accumulation

mutant enzyme tangerine3183

Go to Expression Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

EXPRESSION

ORGANISM

UNIPROT

LITERATURE

a deletion created by CRISPR/Cas9 system in the 5' UTR of the carotenoid isomerase gene in tomato leads to downregulation of the gene resulting in the low conversion of prolycopene to lycopene. Role of 5' UTR region in gene expression regulation

ethylene induces Mhz5 expression, the production of neoxanthin, and abscisic acid accumulation in roots

748913

in wild-type fruit, the mRNA levels of CRTISO increases 10fold during the breaker stage of fruit ripening. Expression of CRTISO in fruit of the mutant tangerine(mic) is similar to that in the wild type

713267

the transcript of Zmcrtiso1 increases throughout endosperm development to day 25 after pollination. Until 30 after pollination the levels decreases

top print hide References Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

REF.

AUTHORS

TITLE

JOURNAL

VOL.

PAGES

YEAR

ORGANISM (UNIPROT)

PUBMED ID

SOURCE

Yu, Q.; Ghisla, S.; Hirschberg, J.; Mann, V.; Beyer, P.

Plant carotene cis-trans isomerase CRTISO: a new member of the FADred-dependent flavopreoteins catalyzing non-redox reactions

J. Biol. Chem.

286

8666-8676

2011

Solanum lycopersicum

21209101

brenda

713267

Isaacson, T.; Ronen, G.; Zamir, D.; Hirschberg, J.

Cloning of tangerine from tomato reveals a carotenoid isomerase essential for the production of beta-carotene and xanthophylls in plants

Plant Cell

333-342

2002

Solanum lycopersicum

11884678

brenda

Chai, C.; Fang, J.; Liu, Y.; Tong, H.; Gong, Y.; Wang, Y.; Liu, M.;, Wang, Y.; Qian, Q.; Cheng, Z.; Chu, C.

ZEBRA2, encoding a carotenoid isomerase, is involved in photoprotection in rice

Plant Mol. Biol.

211-221

2011

Oryza sativa (B0L964), Oryza sativa

21161331

brenda

Li, Q.; Farre, G.; Naqvi, S.; Breitenbach, J.; Sanahuja, G.; Bai, C.; Sandmann, G.; Capell, T.; Christou, P.; Zhu, C.

Cloning and functional characterization of the maize carotenoid isomerase and beta-carotene hydroxylase genes and their regulation during endosperm maturation

Transgenic Res.

1053-1068

2010

Zea mays (C1JFF5), Zea mays

20221689

brenda

Kishimoto, S.; Ohmiya, A.

Carotenoid isomerase is key determinant of petal color of Calendula officinalis

J. Biol. Chem.

287

276-285

2012

Calendula officinalis (G9MAL3), Calendula officinalis (G9MAL5), Calendula officinalis (G9MAL6), Calendula officinalis (G9MAL7), Calendula officinalis (G9MAL8), Calendula officinalis (G9MAL4), Calendula officinalis

22069331

brenda

748913

Yin, C.C.; Ma, B.; Collinge, D.P.; Pogson, B.J.; He, S.J.; Xiong, Q.; Duan, K.X.; Chen, H.; Yang, C.; Lu, X.; Wang, Y.Q.; Zhang, W.K.; Chu, C.C.; Sun, X.H.; Fang, S.; Chu, J.F.; Lu, T.G.; Chen, S.Y.; Zhang, J.S.

Ethylene responses in rice roots and coleoptiles are differentially regulated by a carotenoid isomerase-mediated abscisic acid pathway

Plant Cell

1061-1081

2015

Oryza sativa Japonica Group (Q2R2A6)

25841037

brenda

749018

Liu, L.; Xie, T.; Peng, P.; Qiu, H.; Zhao, J.; Fang, J.; Patil, S.B.; Wang, Y.; Fang, S.; Chu, J.; Yuan, S.; Zhang, W.; Li, X.

Mutations in the MIT3 gene encoding a caroteniod isomerase lead to increased tiller number in rice

Plant Sci.

267

1-10

2018

Oryza sativa Japonica Group (Q2R2A6)

29362087

brenda

Zhao, J.; Fang, Y.; Kang, S.; Ruan, B.; Xu, J.; Dong, G.; Yan, M.; Hu, J.; Zeng, D.; Zhang, G.; Gao, Z.; Guo, L.; Qian, Q.; Zhu, L.

Identification and characterization of a new allele for ZEBRA LEAF 2, a gene encoding carotenoid isomerase in rice

South Afr. J. Bot.

102-111

2014

Oryza sativa Japonica Group (Q2R2A6)

brenda

Li, Z.; Ji, J.; Wang, G.

Cloning and characterization of a Lycium chinense carotenoid isomerase gene enhancing carotenoid accumulation in transgenic tobacco

Transact. Tianjin Univ.

468-476

2015

Lycium chinense (A0A140YIA2)

brenda

Sun, Y.; Xin, Y.; Zhang, L.; Wang, Y.; Liu, R.; Li, X.; Zhou, C.; Zhang, L.; Han, J.

Enhancement of violaxanthin accumulation in Nannochloropsis oceanica by overexpressing a carotenoid isomerase gene from Phaeodactylum tricornutum

Front. Microbiol.

942883

2022

Phaeodactylum tricornutum (B7FWY8), Phaeodactylum tricornutum CCAP 1055/1 (B7FWY8)

36118188

brenda

Pinheiro, T.T.; Peres, L.E.P.; Purgatto, E.; Latado, R.R.; Maniero, R.A.; Martins, M.M.; Figueira, A.

Citrus carotenoid isomerase gene characterization by complementation of the Micro-Tom tangerine mutant

Plant Cell Rep.

623-636

2019

Citrus sinensis

30737538

brenda

Lakshmi Jayaraj, K.; Thulasidharan, N.; Antony, A.; John, M.; Augustine, R.; Chakravartty, N.; Sukumaran, S.; Uma Maheswari, M.; Abraham, S.; Thomas, G.; Lachagari, V.B.R.; Seshagiri, S.; Narayanan, S.; Kuriakose, B.

Targeted editing of tomato carotenoid isomerase reveals the role of 5' UTR region in gene expression regulation

Plant Cell Rep.

621-635

2021

Solanum lycopersicum (Q8S4R4)

33449143

brenda