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Reference on EC 5.1.3.2 - UDP-glucose 4-epimerase and Organism(s) Homo sapiens

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bergren, W.R.; Ng, W.G.; Donnell, G.N.
Uridine diphosphate galactose 4-epimerase in human and other mammalian hemolysates
Biochim. Biophys. Acta
315
464-472
1973
Felis catus, Homo sapiens, Mus musculus
-
Manually annotated by BRENDA team
Daude, N.; Gallaher, T.K.; Zeschnigk, M.; Starzinski-Powitz, A.; Petry, K.G.; Haworth, I.S.; Reichhardt, J.K.V.
Molecular cloning, characterization, and mapping of a full-length cDNA encoding human UDP-galactose 4'-epimerase
Biochem. Mol. Med.
56
1-7
1995
Homo sapiens
Manually annotated by BRENDA team
Thoden, J.B.; Wohlers, T.M.; Fridovich-Keil, J.L.; Holden, H.M.
Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase
Biochemistry
39
5691-5701
2000
Homo sapiens
Manually annotated by BRENDA team
Thoden, J.B.; Wohlers, T.M.; Fridovich-Keil, J.L.; Holden, H.M.
Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site
J. Biol. Chem.
276
15131-15136
2001
Homo sapiens (Q14376), Homo sapiens
Manually annotated by BRENDA team
Holden, H.M.; Rayment, I.; Thoden, J.B.
Structure and function of enzymes of the Leloir pathway for galactose metabolism
J. Biol. Chem.
278
43885-43888
2003
Escherichia coli, Homo sapiens
Manually annotated by BRENDA team
Timson, D.J.
Functional analysis of disease-causing mutations in human UDP-galactose 4-epimerase
FEBS J.
272
6170-6177
2005
Homo sapiens
Manually annotated by BRENDA team
Schulz, J.M.; Watson, A.L.; Sanders, R.; Ross, K.L.; Thoden, J.B.; Holden, H.M.; Fridovich-Keil, J.L.
Determinants of function and substrate specificity in human UDP-galactose 4'-epimerase
J. Biol. Chem.
279
32796-32803
2004
Homo sapiens
Manually annotated by BRENDA team
Schulz, J.M.; Ross, K.L.; Malmstrom, K.; Krieger, M.; Fridovich-Keil, J.L.
Mediators of galactose sensitivity in UDP-galactose 4'-epimerase-impaired mammalian cells
J. Biol. Chem.
280
13493-13502
2005
Escherichia coli, Homo sapiens
Manually annotated by BRENDA team
Urbaniak, M.D.; Tabudravu, J.N.; Msaki, A.; Matera, K.M.; Brenk, R.; Jaspars, M.; Ferguson, M.A.
Identification of novel inhibitors of UDP-Glc 4-epimerase, a validated drug target for african sleeping sickness
Bioorg. Med. Chem. Lett.
16
5744-5747
2006
Homo sapiens, Trypanosoma brucei, Homo sapiens CHO-K1
Manually annotated by BRENDA team
Prodan-Zitnik, I.; Karas-Kuzelicki, N.; Lukac-Bajalo, J.
Positive correlation between galactose-1-phosphate uridyltransferase (GALT) and UDP-galactose-4-epimerase (GALE) activities
Clin. Biochem.
42
1561-1564
2009
Homo sapiens
Manually annotated by BRENDA team
Bang, Y.L.; Nguyen, T.T.; Trinh, T.T.; Kim, Y.J.; Song, J.; Song, Y.H.
Functional analysis of mutations in UDP-galactose-4-epimerase (GALE) associated with galactosemia in Korean patients using mammalian GALE-null cells
FEBS J.
276
1952-1961
2009
Homo sapiens (Q14376), Homo sapiens
Manually annotated by BRENDA team
McCorvie, T.J.; Wasilenko, J.; Liu, Y.; Fridovich-Keil, J.L.; Timson, D.J.
In vivo and in vitro function of human UDP-galactose 4-epimerase variants
Biochimie
93
1747-1754
2011
Homo sapiens
Manually annotated by BRENDA team
Wen, Y.; Qin, J.; Deng, Y.; Wang, H.; Magdalou, J.; Chen, L.
The critical role of UDP-galactose-4-epimerase in osteoarthritis modulating proteoglycans synthesis of the articular chondrocytes
Biochem. Biophys. Res. Commun.
452
906-911
2014
Homo sapiens (Q14376), Homo sapiens
Manually annotated by BRENDA team
Beerens, K.; Soetaert, W.; Desmet, T.
UDP-hexose 4-epimerases a view on structure, mechanism and substrate specificity
Carbohydr. Res.
414
8-14
2015
Marinithermus hydrothermalis (F2NQX6), Thermus thermophilus (F6DEY6), Saccharomyces cerevisiae (P04397), Escherichia coli (P09147), Streptococcus thermophilus (P21977), Homo sapiens (Q14376), Homo sapiens, Drosophila melanogaster (Q9W0P5), Saccharomyces cerevisiae ATCC 204508 / S288c (P04397), Thermus thermophilus SG0.5JP17-16 (F6DEY6), Marinithermus hydrothermalis DSM 14884 / JCM 11576 / T1 (F2NQX6)
Manually annotated by BRENDA team