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Information on EC 5.1.1.14 - nocardicin A epimerase

for references in articles please use BRENDA:EC5.1.1.14

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IUBMB Comments

Requires pyridoxal 5'-phosphate. The enzyme, characterized from the bacterium Nocardia uniformis, is involved in the biosynthesis of the monolactam antibiotic nocardicin A. It catalyses the epimerization of the amino group at position 9' from (S)- configuration to (R)-. The enzyme can act on both isonocardicin A and isonocardicin C, but the in vivo substrate appears to be the latter .

The expected taxonomic range for this enzyme is: Nocardia uniformis

Synonyms
Epimerase, isonocardicin A, nocardicin C-9'epimerase, NocJ, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
isonocardicin A = nocardicin A
show the reaction diagram
(2)
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isonocardicin C = nocardicin C
show the reaction diagram
(1)
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