Reference on EC 4.6.1.14 - glycosylphosphatidylinositol diacylglycerol-lyase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Fox, J.A.; Duszenko, M.; Ferguson, M.A.J.; Low, M.G.; Cross, G.A.M.
Purification and characterization of a novel glycan-phosphatidylinositol-specific phospholipase C from Trypanosoma brucei
J. Biol. Chem.
261
15767-15771
1986
Trypanosoma brucei, Trypanosoma brucei 427
Hereld, D.; Krakow, J.L.; Bangs, J.D.; Hart, G.W.; Englund, P.T.
A phospholipase C from Trypanosoma brucei which selectively cleaves the glycolipid on the variant surface glycoprotein
J. Biol. Chem.
261
13813-13819
1986
Trypanosoma brucei
Fouchier, F.; Baltz, T.; Rougon, G.
Identification of glycosylphosphatidylinositol-specific phospholipases C in mouse brain membranes
Biochem. J.
269
321-327
1990
Mus musculus
Morris, J.C.; Ping-Sheng, L.; Shen, T.Y.; Mensa-Wilmot, K.
Glycan requirements of glycosylphosphatidylinositol phospholipase C from Trypanosoma brucei. Glucosaminylinositol derivatives inhibit phosphatidylinositol phospholipase C
J. Biol. Chem.
270
2517-2524
1995
Trypanosoma brucei
Butikofer, P.; Brodbeck, U.
Partial purification and characterization of a (glycosyl) inositol phospholipid-specific phospholipase C from peanut
J. Biol. Chem.
268
17794-17802
1993
Arachis hypogaea
Mller, G.; Grey, S.; Jung, C.; Bandlow, W.
Insulin-like signaling in yeast: modulation of protein phosphatase 2A, protein kinase A, cAMP-specific phosphodiesterase, and glycosyl-phosphatidylinositol-specific phospholipase C activities
Biochemistry
39
1475-1488
2000
Saccharomyces cerevisiae, Rattus norvegicus
Mller, G.; Deary, E.A.; Korndrfer, A.; Bandlow, W.
Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport
J. Cell Biol.
126
1267-1276
1994
Rattus norvegicus
Mensa-Wilmot, K.; Morris, J.C.; Al-Qahtani, A.; Englund, P.T.
Purification and use of recombinant glycosylphosphatidylinositol-phospholipase C
Methods Enzymol.
250
641-655
1995
Trypanosoma brucei
Rolin, S.; Hanocq-Quertier, J.; Paturiaux-Hanocq, F.; Nolan, D.; Salmon, D.; Webb, H.; Carrington, M.; Voorheis, P.; Pays, E.
Simultaneous but independent activation of adenylate cyclase and glycosylphosphatidylinositol-phospholipase C under stress conditions in Trypanosoma brucei
J. Biol. Chem.
271
10844-10852
1996
Trypanosoma brucei
Webb, H.; Carnall, N.; Vanhamme, L.; Rolin, S.; Van Den Abbeele, J.; Welburn, S.; Pays, E.; Carrington, M.
The GPI-phospholipase C of Trypanosoma brucei is nonessential but influences parasitemia in mice
J. Cell. Biol.
139
103-114
1997
Trypanosoma brucei
Buetikofer, P.; Boschung, M.; Brodbeck, U.; Menon, A.K.
Phosphatidylinositol hydrolysis by Trypanosoma brucei glycosylphosphatidylinositol phospholipase C
J. Biol. Chem.
271
15533-15541
1996
Arachis hypogaea, Trypanosoma brucei
Carnall, N.; Webb, H.; Carrington, M.
Mutagenesis study of the glycosylphosphatidylinositol phospholipase C of Trypanosoma brucei
Mol. Biochem. Parasitol.
90
423-432
1997
Trypanosoma brucei
Carrington, M.; Carnall, N.; Crow, M.S.; Gaud, A.; Redpath, M.B.; Wasunna, C.L.; Webb, H.
The properties and function of the glycosylphosphatidylinositol-phospholipase C in Trypanosoma brucei
Mol. Biochem. Parasitol.
91
153-164
1998
Trypanosoma brucei
Rashid, M.B.; Russell, M.; Mensa-Wilmot, K.
Roles of Gln81 and Cys80 in catalysis by glycosylphosphatidylinositol-phospholipase C from Trypanosoma brucei
Eur. J. Biochem.
264
914-920
1999
Trypanosoma brucei
Armah, D.A.; Mensa-Wilmot, K.
S-myristoylation of a glycosylphosphatidylinositol-specific phospholipase C in Trypanosoma brucei
J. Biol. Chem.
274
5931-5938
1999
Trypanosoma brucei
Ochatt, C.M.; Buetikofer, P.; Navarro, M.; Wirtz, E.; Boschung, M.; Armah, D.; Cross, G.A.
Conditional expression of glycosylphosphatidylinositol phospholipase C in Trypanosoma brucei
Mol. Biochem. Parasitol.
103
35-48
1999
Trypanosoma brucei
Armah, D.A.; Mensa-Wilmot, K.
Tetramerization of glycosylphosphatidylinositol-specific phospholipase C from Trypanosoma brucei
J. Biol. Chem.
275
19334-19342
2000
Trypanosoma brucei
Paturiaux-Hanocq, F.; Hanocq-Quertier, J.; de Almeida, M.L.; Nolan, D.P.; Pays, A.; Vanhamme, L.; Van den Abbeele, J.; Wasunna, C.L.; Carrington, M.; Pays, E.
A role for the dynamic acylation of a cluster of cysteine residues in regulating the activity of the glycosylphosphatidylinositol-specific phospholipase C of Trypanosoma brucei
J. Biol. Chem.
275
12147-12155
2000
Trypanosoma brucei
Mller, G.; Schulz, A.; Wied, S.; Frick, W.
Regulation of lipid raft proteins by glimepiride- and insulin-induced glycosylphosphatidylinositol-specific phospholipase C in rat adipocytes
Biochem. Pharmacol.
69
761-780
2005
Bacillus cereus, Rattus norvegicus, Trypanosoma brucei
Zheng, Z.; Butler, K.D.; Tweten, R.K.; Mensa-Wilmot, K.
Endosomes, glycosomes, and glycosylphosphatidylinositol catabolism in Leishmania major
J. Biol. Chem.
279
42106-42113
2004
Trypanosoma brucei
Gruszynski, A.E.; van Deursen, F.J.; Albareda, M.C.; Best, A.; Chaudhary, K.; Cliffe, L.J.; Del Rio, L.; Dunn, J.D.; Ellis, L.; Evans, K.J.; Figueiredo, J.M.; Malmquist, N.A.; Omosun, Y.; Palenchar, J.B.; Prickett, S.; Punkosdy, G.A.; van Dooren, G.; Wang, Q.; Menon, A.K.; Matthews, K.R.; Bangs, J.D.
Regulation of surface coat exchange by differentiating African trypanosomes
Mol. Biochem. Parasitol.
147
211-223
2006
Trypanosoma brucei
Subramanya, S.; Mensa-Wilmot, K.
Regulated cleavage of intracellular glycosylphosphatidylinositol in a trypanosome. Peroxisome-to-endoplasmic reticulum translocation of a phospholipase C
FEBS J.
273
2110-2126
2006
Trypanosoma brucei, Trypanosoma brucei 427
Subramanya, S.; Hardin, C.F.; Steverding, D.; Mensa-Wilmot, K.
Glycosylphosphatidylinositol-specific phospholipase C regulates transferrin endocytosis in the African trypanosome
Biochem. J.
417
685-694
2009
Trypanosoma brucei
Mueller, G.; Wied, S.; Jung, C.; Over, S.
Hydrogen peroxide-induced translocation of glycolipid-anchored (c)AMP-hydrolases to lipid droplets mediates inhibition of lipolysis in rat adipocytes
Br. J. Pharmacol.
154
901-913
2008
Rattus norvegicus
Subramanya, S.; Armah, D.A.; Mensa-Wilmot, K.
Trypanosoma brucei: reduction of GPI-phospholipase C protein during differentiation is dependent on replication of newly transformed cells
Exp. Parasitol.
125
222-229
2010
Trypanosoma brucei
Davies, A.; Kadurin, I.; Alvarez-Laviada, A.; Douglas, L.; Nieto-Rostro, M.; Bauer, C.S.; Pratt, W.S.; Dolphin, A.C.
The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function
Proc. Natl. Acad. Sci. USA
107
1654-1659
2010
Trypanosoma brucei
Xing, Y.; Gu, Y.; Xu, L.C.; Siedlecki, C.A.; Donahue, H.J.; You, J.
Effects of membrane cholesterol depletion and GPI-anchored protein reduction on osteoblastic mechanotransduction
J. Cell. Physiol.
226
2350,235-9
2010
Mus musculus
Sunter, J.; Webb, H.; Carrington, M.
Determinants of GPI-PLC localisation to the flagellum and access to GPI-anchored substrates in trypanosomes
PLoS Pathog.
9
e1003566
2013
Trypanosoma brucei, Trypanosoma brucei 427, Trypanosoma congolense
Van Veen, M.; Matas-Rico, E.; van de Wetering, K.; Leyton-Puig, D.; Kedziora, K.; de Lorenzi, V.; Stijf-Bultsma, Y.; van den Broek, B.; Jalink, K.; Sidenius, N.; Perrakis, A.; Moolenaar, W.
Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells
eLife
6
e23649
2017
Homo sapiens (Q9HCC8)
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