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Information on EC 4.4.1.34 - isoprene-epoxide-glutathione S-transferase

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IUBMB Comments
The enzyme, characterized from the bacterium Rhodococcus sp. AD45, is involved in isoprene degradation. The enzyme can catalyse the glutathione-dependent ring opening of various epoxides, but the highest activity is with (3R)-3,4-epoxy-3-methylbut-1-ene, which is derived from isoprene by EC 1.14.13.69, alkene monooxygenase.
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The expected taxonomic range for this enzyme is: Rhodococcus sp.
Synonyms
IsoI, isol, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-(glutathion-S-yl)-2-methylbut-3-en-1-ol = (3R)-3,4-epoxy-3-methylbut-1-ene + glutathione
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PATHWAY SOURCE
PATHWAYS
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