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Information on EC 4.4.1.22 - S-(hydroxymethyl)glutathione synthase

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EC Tree
IUBMB Comments
The enzyme from Paracoccus denitrificans accelerates the spontaneous reaction in which the adduct of formaldehyde and glutathione is formed, i.e. the substrate for EC 1.1.1.284, S-(hydroxymethyl)glutathione dehydrogenase, in the formaldehyde-detoxification pathway.
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The enzyme appears in viruses and cellular organisms
Synonyms
glutathione-dependent formaldehyde-activating enzyme, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-(hydroxymethyl)glutathione = glutathione + formaldehyde
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