Disease on EC 4.4.1.13 - cysteine-S-conjugate beta-lyase
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Acquired Immunodeficiency Syndrome
Tryptophan metabolism in relation to amino acid alterations during typhoid fever.
Anemia, Hypochromic
Rhizobitoxine production and symbiotic compatibility of Bradyrhizobium from Asian and North American lineages of amphicarpaea.
Basal Ganglia Diseases
Immunocytochemical localization of kynurenine aminotransferase in the rat striatum: a light and electron microscopic study.
Carcinogenesis
Upregulation of the Glutaminase II Pathway Contributes to Glutamate Production upon Glutaminase 1 Inhibition in Pancreatic Cancer.
Carcinoma, Hepatocellular
A Novel mRNA-Mediated and MicroRNA-Guided Approach to Specifically Eradicate Drug-Resistant Hepatocellular Carcinoma Cell Lines by Se-Methylselenocysteine.
Cataract
Presence and distribution of l-kynurenine aminotransferases immunoreactivity in human cataractous lenses.
Central Nervous System Neoplasms
Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015).
Diphtheria
Characterization of C-S Lyase from C. diphtheriae: A Possible Target for New Antimicrobial Drugs.
Herpes Simplex
Effect of urethral wall injection of replication-defective herpes simplex virus-mediated gene transfer of kynurenine aminotransferase on urethral pressure in spinal cord-injured rats.
Herpes Simplex
Herpes simplex virus vector-mediated gene transfer of kynurenine aminotransferase improves detrusor overactivity in spinal cord-injured rats.
Huntington Disease
An investigation of the activities of 3-hydroxykynureninase and kynurenine aminotransferase in the brain in Huntington's disease.
Huntington Disease
Characterization of kynurenine aminotransferase III, a novel member of a phylogenetically conserved KAT family.
Huntington Disease
Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015).
Hyperoxaluria
Metabolism of Oxalate in Humans: A Potential Role Kynurenine Aminotransferase/Glutamine Transaminase/Cysteine Conjugate Beta-lyase Plays in Hyperoxaluria.
Ischemic Stroke
Serum indoleamine 2,3-dioxygenase and kynurenine aminotransferase enzyme activity in patients with ischemic stroke.
Melanoma
Presence and distribution of l-kynurenine aminotransferases immunoreactivity in human cataractous lenses.
Melanoma
Presence of L-kynurenine aminotransferase III in retinal ganglion cells and corpora amylacea in the human retina and optic nerve.
Neoplasms
High Levels of Glutaminase II Pathway Enzymes in Normal and Cancerous Prostate Suggest a Role in 'Glutamine Addiction'.
Neoplasms
Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015).
Neoplasms
Perchloroethylene-induced rat kidney tumors: an investigation of the mechanisms involved and their relevance to humans.
Neoplasms
Upregulation of the Glutaminase II Pathway Contributes to Glutamate Production upon Glutaminase 1 Inhibition in Pancreatic Cancer.
Nervous System Diseases
Characterization of kynurenine aminotransferase III, a novel member of a phylogenetically conserved KAT family.
Neuralgia
Kynurenine, Tetrahydrobiopterin, and Cytokine Inflammatory Biomarkers in Individuals Affected by Diabetic Neuropathic Pain.
Neurodegenerative Diseases
Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015).
Osteosarcoma
Toxicity of Bordetella avium beta-cystathionase toward MC3T3-E1 osteogenic cells.
Overweight
TSH levels, overweight, BMI, and skin expression levels of DCT and CCBL2 genes are related to vitiligo treatment response with narrow band UVB phototherapy.
Proteinuria
Nephrotoxicity of sevoflurane compound A [fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether] in rats: evidence for glutathione and cysteine conjugate formation and the role of renal cysteine conjugate beta-lyase.
Renal Insufficiency, Chronic
Long-Term Clinical Outcomes and Optimal Stent Strategy in Left Main Coronary Bifurcation Stenting.
Seizures
Differential expression of the astrocytic enzymes 3-hydroxyanthranilic acid oxygenase, kynurenine aminotransferase and glutamine synthetase in seizure-prone and non-epileptic mice.
Seizures
Electrical kindling is associated with a lasting increase in the extracellular levels of kynurenic acid in the rat hippocampus.
Seizures
Proconvulsive effects of the mitochondrial respiratory chain inhibitor--3-nitropropionic acid.
Starvation
Expression in Lactococcus lactis of functional genes related to amino acid catabolism and cheese aroma formation is influenced by branched chain amino acids.
Tuberculosis
Serum Small Extracellular Vesicles Proteome of Tuberculosis Patients Demonstrated Deregulated Immune Response.
Vitamin B 6 Deficiency
Multiple roles of haem in cystathionine ?-synthase activity: implications for hemin and other therapies of acute hepatic porphyria.
Vitiligo
TSH levels, overweight, BMI, and skin expression levels of DCT and CCBL2 genes are related to vitiligo treatment response with narrow band UVB phototherapy.
Yellow Fever
Isolation, characterization, and functional expression of kynurenine aminotransferase cDNA from the yellow fever mosquito, Aedes aegypti(1).
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