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Information on EC 4.3.2.9 - gamma-glutamylcyclotransferase

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EC Tree
     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.2 Amidine-lyases
                4.3.2.9 gamma-glutamylcyclotransferase
IUBMB Comments
The enzyme, found in animals and plants, acts on derivatives of L-glutamate, L-2-aminobutanoate, L-alanine and glycine. The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the alpha-amine of the L-glutamyl residue, releasing it as the cyclic 5-oxo-L-proline.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
A2LD1, C7orf24, C7orf24 protein, cyclotransferase, gamma-glutamyl, gamma-glutamyl cyclotransferase, gamma-glutamyl cyclotransferases, gamma-glutamyl-amino acid cyclotransferase, gamma-glutamylamine cyclotransferase, gamma-glutamyltranspeptidase, gamma-L-glutamylcyclotransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
alpha-(gamma-L-glutamyl)-L-amino acid = alpha-L-amino acid + 5-oxo-L-proline
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PATHWAY SOURCE
PATHWAYS
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