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Information on EC 4.3.2.3 - ureidoglycolate lyase and Organism(s) Pseudomonas aeruginosa

for references in articles please use BRENDA:EC4.3.2.3
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EC Tree
     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.2 Amidine-lyases
                4.3.2.3 ureidoglycolate lyase
IUBMB Comments
This microbial enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 3.5.1.116, ureidoglycolate amidohydrolase, which releases ammonia rather than urea.
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Select one or more organisms in this record: ?
This record set is specific for:
Pseudomonas aeruginosa
Word Map
  • 4.3.2.3
  • pituitary
  • neuropeptide
  • endoproteolytic
  • glycine-extended
  • alpha-hydroxylating
  • 1.14.17.3
  • prohormone
  • neurointermediate
  • corticotrope
  • glucuronyl
  • ascorbate-dependent
  • cuproenzymes
  • granule-associated
  • allantoicase
  • beta-monooxygenase
  • uteroglobin
The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The enzyme appears in selected viruses and cellular organisms
Synonyms
(-)-ureidoglycolate urea-lyase, allA, DAL3, lyase, ureidoglycolate, PAL, PAM, peptidyl-alpha-hydroxyglycine alpha-amidating lyase, peptidylglycine alpha-amidating monooxygenase, UGL, ureidoglycolase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
(-)-ureidoglycolate urea-lyase
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-
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lyase, ureidoglycolate
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-
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UGL
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-
ureidoglycolase
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-
-
-
ureidoglycolatase
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ureidoglycolate hydrolase
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SYSTEMATIC NAME
IUBMB Comments
(S)-ureidoglycolate urea-lyase (glyoxylate-forming)
This microbial enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 3.5.1.116, ureidoglycolate amidohydrolase, which releases ammonia rather than urea.
CAS REGISTRY NUMBER
COMMENTARY hide
9014-57-7
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ureidoglycolate
?
show the reaction diagram
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-
-
-
-
ureidoglycolate
glyoxylate + urea
show the reaction diagram
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r
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ureidoglycolate
?
show the reaction diagram
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-
-
-
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
Sequence
A0A2R3ILG3_PSEAI
169
0
19041
TrEMBL
A0A485E7G8_PSEAI
270
0
28849
TrEMBL
A0A0F6UF35_PSEAI
169
0
18967
TrEMBL
A0A080VRW8_PSEAI
169
0
19014
TrEMBL
A0A485E879_PSEAI
143
0
15889
TrEMBL
A0A069Q972_PSEAI
169
0
18983
TrEMBL
A0A2S5IDS5_PSEAI
167
0
18736
TrEMBL
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
70
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15 min, in presence of Mn2+, complete inactivation
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Trijbels, F.; Vogels, G.D.
Allantoate and ureidoglycolate degradation by Pseudomonas aeruginosa
Biochim. Biophys. Acta
132
115-126
1967
Pseudomonas aeruginosa
Manually annotated by BRENDA team
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