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Information on EC 4.3.1.28 - L-lysine cyclodeaminase

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EC Tree
     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.1 Ammonia-lyases
                4.3.1.28 L-lysine cyclodeaminase
IUBMB Comments
Requires bound NAD+. The enzyme produces the non-proteinogenic amino acid L-pipecolate, which is incorporated into multiple secondary metabolite products, including rapamycin, tobulysin, virginiamycin and pristinamycin.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
fkbL, LCD, lysine cyclodeaminase, rapL, tubZ, visC, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-lysine = L-pipecolate + NH3
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