We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Information on EC 4.2.3.26 - R-linalool synthase for references in articles please use BRENDA:EC4.2.3.26
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments Geranyl diphosphate cannot be replaced by isopentenyl diphosphate, dimethylallyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as substrate . Requires Mg2+ or Mn2+ for activity. Unlike many other monoterpene synthases, only a single product, (3R)-linalool, is formed.
The enzyme appears in viruses and cellular organisms
Synonyms
lemts1,
more
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(R)-linalool synthase
-
-
(R)-linalool synthase
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
geranyl diphosphate + H2O = (3R)-linalool + diphosphate
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming]
Geranyl diphosphate cannot be replaced by isopentenyl diphosphate, dimethylallyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as substrate [1]. Requires Mg2+ or Mn2+ for activity. Unlike many other monoterpene synthases, only a single product, (3R)-linalool, is formed.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
farnesyl diphosphate
(E)-nerolidol + diphosphate
-
-
-
?
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
-
-
-
-
?
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
-
-
-
-
?
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
-
-
-
?
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
-
-
-
-
?
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
-
-
-
?
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
-
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
-
-
-
-
?
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
A0A2Z4XFW0
-
-
-
?
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
-
-
-
-
?
geranyl diphosphate + H2O
(3R)-linalool + diphosphate
Q1XBU5
-
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
additional information
-
Mn2+ may not substitute for Mg2+
Mg2+
-
Km-value 4.6 mM, isoenzyme QH1
Mn2+
may substitute for Mg2+
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
EDTA
-
up to 95% loss of activity, isoenzyme QH1, full reactivation by 10 mM Mg2+
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
additional information
expression in leaves is induced by spider mite-infestation and wounding
-
additional information
-
expression in leaves is induced by spider mite-infestation and wounding
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.025 - 0.064
geranyl diphosphate
0.025
geranyl diphosphate
pH 6.5
0.064
geranyl diphosphate
-
isoenzyme QH1, pH 7.0, 30°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.24
geranyl diphosphate
pH 6.5
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
7.5
half-maximal velocity
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
6.22
-
isoenzyme QH1, calculated
6.6
-
isoenzyme QH5, calculated
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
isoenzyme QH1 and QH5
-
-
brenda
-
-
-
brenda
-
UniProt
brenda
champak
-
-
brenda
expression in Escherichia coli
Swissprot
brenda
-
UniProt
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
of stem, isoenzyme QH5, induction by wounding
brenda
-
-
brenda
-
both isoenzyme QH1 and QH5
brenda
-
brenda
-
brenda
additional information
-
not: stem stele, root
brenda
-
brenda
-
-
brenda
-
brenda
-
both isoenzyme QH1 and QH5, induction by wounding
brenda
-
brenda
-
brenda
-
epidermis of, isoenzyme QH5, induction by wounding
brenda
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
metabolism
-
the enzyme is essential for the production of major volatile organic compounds of champak flowers, (R)-linalool and linalool oxides
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
LALIN_LAVAN
564
0
65654
Swiss-Prot
LLOS1_ARTAN
567
0
65701
Swiss-Prot
LLOS1_ARTAN
567
0
65701
Swiss-Prot
LLOS5_ARTAN
583
0
67390
Swiss-Prot
LLOS_MENAQ
606
0
70535
Swiss-Prot
LLOS_OCIBA
574
0
65822
Swiss-Prot
LNSA_STRC2
Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)
329
0
36397
Swiss-Prot
A0A2G9HTP3_9LAMI
296
0
33759
TrEMBL
A0A023UAW9_9LAMI
586
0
66928
TrEMBL
A0A2Z4XFW0_9LAMI
564
0
65771
TrEMBL
Q1XBU5_SOLLC
609
0
70945
TrEMBL
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)
Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)
Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
65700
-
x * 65700, isoenzyme QH1, x * 67400, isoenzyme QH5, calculated
67400
-
x * 65700, isoenzyme QH1, x * 67400, isoenzyme QH5, calculated
70500
x * 70500, calculated
70800
predicted molecular mass
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
?
-
x * 65700, isoenzyme QH1, x * 67400, isoenzyme QH5, calculated
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
additional information
sequence contains a plastidial transit peptide
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
addition of bovine serum albumine, cytochrome c, or carbonic anhydrase stabilizes with concommittant increase in both Km- and kcat-value
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
both isoenzyme QH1 and QH5, partial
-
Ni-NTA Sepharose resin column chromatography
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
expressed in Escherichia coli BL21 pLysS cells
-
into the pET32-a vector for expression in Escherichia coli BL21DE3 cells
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
EDTA-inactivated isoenzyme QH1, full reactivation by 10 mM Mg2+
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Jia, J.W.; Crock, J.; Lu, S.; Croteau, R.; Chen, X.Y.
(3R)-Linalool synthase from Artemisia annua L.: cDNA isolation, characterization, and wound induction
Arch. Biochem. Biophys.
372
143-149
1999
Artemisia annua
brenda
Crowell, A.L.; Williams, D.C.; Davis, E.M.; Wildung, M.R.; Croteau, R.
Molecular cloning and characterization of a new linalool synthase
Arch. Biochem. Biophys.
405
112-121
2002
Mentha aquatica var. citrata (Q8H2B4)
brenda
van Schie, C.C.; Haring, M.A.; Schuurink, R.C.
Tomato linalool synthase is induced in trichomes by jasmonic acid
Plant Mol. Biol.
64
251-263
2007
Solanum lycopersicum (Q1XBU5), Solanum lycopersicum
brenda
Dhandapani, S.; Jin, J.; Sridhar, V.; Sarojam, R.; Chua, N.; Jang, I.
Integrated metabolome and transcriptome analysis of Magnolia champaca identifies biosynthetic pathways for floral volatile organic compounds
BMC Genomics
18
463
2017
Magnolia champaca
brenda
Pragadheesh, V.S.; Chanotiya, C.S.; Rastogi, S.; Shasany, A.K.
Scent from Jasminum grandiflorum flowers Investigation of the change in linalool enantiomers at various developmental stages using chemical and molecular methods
Phytochemistry
140
83-94
2017
Jasminum grandiflorum
brenda
Adal, A.M.; Sarker, L.S.; Malli, R.P.N.; Liang, P.; Mahmoud, S.S.
RNA-Seq in the discovery of a sparsely expressed scent-determining monoterpene synthase in lavender (Lavandula)
Planta
249
271-290
2019
Lavandula x intermedia (A0A2Z4XFW0)
brenda
Select items on the left to see more content.
html completed