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Reference on EC 4.2.3.124 - 2-deoxy-scyllo-inosose synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Nango, E.; Kumasaka, T.; Sato, T.; Tanaka, N.; Kakinuma, K.; Eguchi, T.
Crystallization and X-ray analysis of 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics
Acta Crystallogr. Sect. F
61
709-711
2005
Niallia circulans (Q9S5E2), Niallia circulans, Niallia circulans SANK72073 (Q9S5E2)
Manually annotated by BRENDA team
Huang, Z.; Kakinuma, K.; Eguchi, T.
Stereospecificity of hydride transfer in NAD+-catalyzed 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics
Bioorg. Chem.
33
82-89
2005
Niallia circulans (Q9S5E2)
Manually annotated by BRENDA team
Hirayama, T.; Kudo, F.; Huang, Z.; Eguchi, T.
Role of glutamate 243 in the active site of 2-deoxy-scyllo-inosose synthase from Bacillus circulans
Bioorg. Med. Chem.
15
418-423
2007
Niallia circulans (Q9S5E2), Niallia circulans
Manually annotated by BRENDA team
Iwase, N.; Kudo, F.; Yamauchi, N.; Kakinuma, K.
Substrate specificity of 2-deoxy-scyllo-inosose synthase, the starter enzyme for 2-deoxystreptamine biosynthesis, toward deoxyglucose-6-phosphates and proposed mechanism
Biosci. Biotechnol. Biochem.
62
2396-2407
1998
Niallia circulans (Q9S5E2), Niallia circulans SANK72073 (Q9S5E2)
Manually annotated by BRENDA team
Tamegai, H.; Nango, E.; Koike-Takeshita, A.; Kudo, F.; Kakinuma, K.
Significance of the 20-kDa subunit of heterodimeric 2-deoxy-scyllo-inosose synthase for the biosynthesis of butirosin antibiotics in Bacillus circulans
Biosci. Biotechnol. Biochem.
66
1538-1545
2002
Niallia circulans (Q9S5E2), Niallia circulans, Niallia circulans SANK72073 (Q9S5E2)
Manually annotated by BRENDA team
Tamegai, H.; Sawada, H.; Nango, E.; Aoki, R.; Hirakawa, H.; Iino, T.; Eguchi, T.
Roles of a 20 kDa protein associated with a carbocycle-forming enzyme involved in aminoglycoside biosynthesis in primary and secondary metabolism
Biosci. Biotechnol. Biochem.
74
1215-1219
2010
Niallia circulans (Q9S5E2), Niallia circulans, Niallia circulans SANK72073 (Q9S5E2)
Manually annotated by BRENDA team
Thuy, M.L.; Kharel, M.K.; Lamichhane, R.; Lee, H.C.; Suh, J.W.; Liou, K.; Sohng, J.K.
Expression of 2-deoxy-scyllo-inosose synthase (kanA) from kanamycin gene cluster in Streptomyces lividans
Biotechnol. Lett.
27
465-470
2005
Streptomyces lividans
Manually annotated by BRENDA team
Nango, E.; Kudo, F.; Eguchi, T.; Kakinuma, K.
Reaction stereochemistry of 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine
Chem. Lett.
32
438-439
2003
Niallia circulans (Q9S5E2)
-
Manually annotated by BRENDA team
Kudo, F.; Yamauchi, N.; Suzuki, R.; Kakinuma, K.
Kinetic isotope effect and reaction mechanism of 2-deoxy-scyllo-inosose synthase derived from butirosin-producing Bacillus circulans
J. Antibiot.
50
424-428
1997
Niallia circulans (Q9S5E2), Niallia circulans, Niallia circulans SANK72073 (Q9S5E2)
Manually annotated by BRENDA team
Kudo, F.; Tamegai, H.; Fujiwara, T.; Tagami, U.; Hirayama, K.; Kakinuma, K.
Molecular cloning of the gene for the key carbocycle-forming enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics and its comparison with dehydroquinate synthase
J. Antibiot.
52
559-571
1999
Streptomyces fradiae, Niallia circulans (Q9S5E2), Niallia circulans, Streptomyces fradiae IFO 13147, Niallia circulans SANK72073 (Q9S5E2)
Manually annotated by BRENDA team
Kudo, F.; Hosomi, Y.; Tamegai, H.; Kakinuma, K.
Purification and characterization of 2-deoxy-scyllo-inosose synthase derived from Bacillus circulans. A crucial carbocyclization enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics
J. Antibiot.
52
81-88
1999
Niallia circulans (Q9S5E2), Niallia circulans, Niallia circulans SANK72073 (Q9S5E2)
Manually annotated by BRENDA team
Hirayama, T.; Tamegai, H.; Kudo, F.; Kojima, K.; Kakinuma, K.; Eguchi, T.
Biosynthesis of 2-deoxystreptamine-containing antibiotics in Streptoalloteichus hindustanus JCM 3268: characterization of 2-deoxy-scyllo-inosose synthase
J. Antibiot.
59
358-361
2006
Streptoalloteichus hindustanus, Streptoalloteichus hindustanus JCM 3268
Manually annotated by BRENDA team
Kogure, T.; Wakisaka, N.; Takaku, H.; Takagi, M.
Efficient production of 2-deoxy-scyllo-inosose from D-glucose by metabolically engineered recombinant Escherichia coli
J. Biotechnol.
129
502-509
2007
Niallia circulans (Q9S5E2), Niallia circulans, Niallia circulans SANK72073 (Q9S5E2)
Manually annotated by BRENDA team
Kharel, M.; Subba, B.; Lee, H.; Liou, K.; Woo, J.; Kim, D.; Moon, Y.; Sohng, J.
Identification of 2-deoxy-scyllo-inosose synthase in aminoglycoside producer Streptomyces
J. Microbiol. Biotechnol.
13
828-831
2003
no activity in Streptomyces lividans, Streptomyces kanamyceticus, Streptomyces ribosidificus, Streptoalloteichus tenebrarius, Streptoalloteichus tenebrarius IFO 13396, Streptomyces kanamyceticus IFO13414, no activity in Streptomyces lividans TK24, Streptomyces ribosidificus IFO13796
-
Manually annotated by BRENDA team
Nango, E.; Eguchi, T.; Kakinuma, K.
Active site mapping of 2-deoxy-scyllo-inosose synthase, the key starter enzyme for the biosynthesis of 2-deoxystreptamine. Mechanism-based inhibition and identification of lysine-141 as the entrapped nucleophile
J. Org. Chem.
69
593-600
2004
Niallia circulans (Q9S5E2), Niallia circulans SANK72073 (Q9S5E2)
Manually annotated by BRENDA team
Nango, E.; Kumasaka, T.; Hirayama, T.; Tanaka, N.; Eguchi, T.
Structure of 2-deoxy-scyllo-inosose synthase, a key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics, in complex with a mechanism-based inhibitor and NAD+
Proteins
70
517-527
2008
Niallia circulans (Q9S5E2), Niallia circulans, Niallia circulans SANK72073 (Q9S5E2)
Manually annotated by BRENDA team
Watanabe, S.; Ozawa, H.; Kato, H.; Nimura-Matsune, K.; Hirayama, T.; Kudo, F.; Eguchi, T.; Kakinuma, K.; Yoshikawa, H.
Carbon-free production of 2-deoxy-scyllo-inosose (DOI) in cyanobacterium Synechococcus elongatus PCC 7942
Biosci. Biotechnol. Biochem.
82
161-165
2018
Niallia circulans (Q9S5E2), Niallia circulans
Manually annotated by BRENDA team
Lim, J.H.; Hwang, H.H.; Lee, N.J.; Lee, J.W.; Seo, E.G.; Son, H.B.; Kim, H.J.; Yoon, Y.J.; Park, J.W.
Enhanced biosynthesis of 2-deoxy-scyllo-inosose in metabolically engineered Bacillus subtilis recombinants
Front. Microbiol.
9
2333
2018
Streptoalloteichus tenebrarius (Q2MF16), Streptoalloteichus tenebrarius, Niallia circulans (Q9S5E2), Streptoalloteichus tenebrarius ATCC 17920 (Q2MF16)
Manually annotated by BRENDA team