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Information on EC 4.2.2.11 - guluronate-specific alginate lyase

for references in articles please use BRENDA:EC4.2.2.11

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IUBMB Comments

The enzyme catalyses the degradation of alginate by a β-elimination reaction. It cleaves the (1→4) bond between α-L-guluronate and either α-L-guluronate or β-D-mannuronate, generating oligosaccharides with 4-deoxy-α-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and α-L-guluronate at the reducing end. Depending on the composition of the substrate, the enzyme produces oligosaccharides ranging from two to six residues, with preference for shorter products. cf. EC 4.2.2.3, mannuronate-specific alginate lyase.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
algmytc, guluronate-specific alginate lyase, guluronate lyase, alya1pl7, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and alpha-L-guluronate at their reducing end
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
alginate degradation
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