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Information on EC 4.2.1.172 - trans-4-hydroxy-L-proline dehydratase

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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.172 trans-4-hydroxy-L-proline dehydratase
IUBMB Comments
The enzyme has been characterized from the bacterium Peptoclostridium difficile. The active form contains a glycyl radical that is generated by a dedicated activating enzyme via chemistry involving S-adenosyl-L-methionine (SAM) and a [4Fe-4S] cluster.
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The enzyme appears in viruses and cellular organisms
Synonyms
t4LHypD, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
trans-4-hydroxy-L-proline = (S)-1-pyrroline-5-carboxylate + H2O
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PATHWAY SOURCE
PATHWAYS
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