Reference on EC 4.1.2.38 - benzoin aldolase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Gonzales, B.; Vicuna, R.
Benzaldehyde lyase, a novel thiamine PPi-requiring enzyme, from Pseudomonas fluorescens biovar I
J. Bacteriol.
171
2401-2405
1989
Pseudomonas fluorescens
Demir, A.S.; Sesenoglu, O.; Dunkelmann, P.; Muller, M.
Benzaldehyde lyase-catalyzed enantioselective carboligation of aromatic aldehydes with mono- and dimethoxy acetaldehyde
Org. Lett.
5
2047-2050
2003
Pseudomonas fluorescens
Hinrichsen, P.; Gomez, I.; Vicuna, R.
Cloning and sequencing of the gene encoding benzaldehyde lyase from Pseudomonas fluorescens biovar I
Gene
144
137-138
1994
Pseudomonas fluorescens
Mosbacher, T.G.; Mueller, M.; Schulz, G.E.
Structure and mechanism of the ThDP-dependent benzaldehyde lyase from Pseudomonas fluorescens
FEBS J.
272
6067-6076
2005
Pseudomonas fluorescens
Kurlemann, N.; Liese, A.
Immobilization of benzaldehyde lyase and its application as a heterogeneous catalyst in the continuous synthesis of a chiral 2-hydroxy ketone
Tetrahedron
15
2955-2958
2004
Escherichia coli, Escherichia coli SG13009/BALHIS
-
Hischer, T.; Gocke, D.; Fernandez, M.; Hoyos, P.; Alcantara, A.R.; Sinisterra, J.V.; Hartmeier, W.; Ansorge-Schumacher, M.B.
Stereoselective synthesis of novel benzoins catalysed by benzaldehyde lyase in a gel-stabilised two-phase system
Tetrahedron
61
7378-7383
2005
Pseudomonas fluorescens
-
Maraite, A.; Schmidt, T.; Ansoerge-Schumacher, M.B.; Brzozowski, A.M.; Grogan, G.
Structure of the ThDP-dependent enzyme benzaldehyde lyase refined to 1.65 A resolution
Acta Crystallogr. Sect. F
F63
546-548
2007
Pseudomonas fluorescens
Janzen, E.; Mueller, M.; Kolter-Jung, D.; Kneen, M.M.; McLeish, M.J.; Pohl, M.
Characterization of benzaldehyde lyase from Pseudomonas fluorescens: A versatile enzyme for asymmetric C-C bond formation
Bioorg. Chem.
34
345-361
2006
Pseudomonas fluorescens
Hildebrand, F.; Kuehl, S.; Pohl, M.; Vasic-Racki, D.; Mueller, M.; Wandrey, C.; Luetz, S.
The production of (R)-2-hydroxy-1-phenyl-propan-1-one derivatives by benzaldehyde lyase from Pseudomonas fluorescens in a continuously operated membrane reactor
Biotechnol. Bioeng.
96
835-843
2007
Pseudomonas fluorescens
Ansorge-Schumacher, M.B.; Greiner, L.; Schroeper, F.; Mirtschin, S.; Hischer, T.
Operational concept for the improved synthesis of (R)-3,3-furoin and related hydrophobic compounds with benzaldehyde lyase
Biotechnol. J.
1
564-568
2006
Pseudomonas fluorescens
Kuehl, S.; Zehentgruber, D.; Pohl, M.; Mueller, M.; Luetz, S.
Process development for enzyme catalysed asymmetric C-C-bond formation
Chem. Eng. Sci.
62
5201-5205
2007
Pseudomonas fluorescens
-
Knoll, M.; Mueller, M.; Pleiss, J.; Pohl, M.
Factors mediating activity, selectivity, and substrate specificity for the thiamin diphosphate-dependent enzymes benzaldehyde lyase and benzoylformate decarboxylase
Chembiochem
7
1928-1934
2006
Pseudomonas fluorescens
Mikolajek, R.; Spiess, A.C.; Pohl, M.; Lamare, S.; Buechs, J.
An activity, stability and selectivity comparison of propioin synthesis by thiamine diphosphate-dependent enzymes in a solid/gas bioreactor
Chembiochem
8
1063-1070
2007
Pseudomonas fluorescens
Calik, P.; Yilgoer, P.; Demir, A.S.
Influence of controlled-pH and uncontrolled-pH operations on recombinant benzaldehyde lyase production by Escherichia coli
Enzyme Microb. Technol.
38
617-627
2006
Pseudomonas fluorescens
-
Dominguez de Maria, P.; Pohl, M.; Gocke, D.; Groeger, H.; Trauthwein, H.; Stillger, T.; Walter, L.; Mueller, M.
Asymmetric synthesis of aliphatic 2-hydroxy ketones by enzymatic carboligation of aldehydes
Eur. J. Org. Chem.
2007
2940-2944
2007
Pseudomonas fluorescens
-
Mikolajek, R.; Spiess, A.C.; Buechs, J.
Feasibility of gas/solid carboligation: conversion of benzaldehyde to benzoin using thiamine diphosphate-dependent enzymes
J. Biotechnol.
129
723-725
2007
Pseudomonas fluorescens
Dominguez de Maria, P.; Stillger, T.; Pohl, M.; Wallert, S.; Drauz, K.; Groeger, H.; Trauthwein, H.; Liese, A.
Preparative enantioselective synthesis of benzoins and (R)-2-hydroxy-1-phenylpropanone using benzaldehyde lyase
J. Mol. Catal. B
38
43-47
2006
Pseudomonas fluorescens
-
Stillger, T.; Pohl, M.; Wandrey, C.; Liese, A.
Reaction engineering of benzaldehyde lyase from Pseudomonas fluorescens catalyzing enantioselective C-C bond formation
Org. Proc. Res. Dev.
10
1172-1177
2006
Pseudomonas fluorescens
-
Dominguez de Maria, P.; Stillger, T.; Pohl, M.; Kiesel, M.; Liese, A.; Groeger, H.; Trauthwein, H.
Enantioselective C-C bond ligation using recombinant Escherichia coli-whole-cell biocatalysts
Adv. Synth. Catal.
350
165-173
2008
Pseudomonas fluorescens
-
Chakraborty, S.; Nemeria, N.; Yep, A.; McLeish, M.J.; Kenyon, G.L.; Jordan, F.
Mechanism of benzaldehyde lyase studied via thiamin diphosphate-bound intermediates and kinetic isotope effects
Biochemistry
47
3800-3809
2008
Pseudomonas fluorescens (P51853)
Brandt, G.S.; Nemeria, N.; Chakraborty, S.; McLeish, M.J.; Yep, A.; Kenyon, G.L.; Petsko, G.A.; Jordan, F.; Ringe, D.
Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester
Biochemistry
47
7734-7743
2008
Pseudomonas fluorescens
Zavrel, M.; Schmidt, T.; Michalik, C.; Ansorge-Schumacher, M.; Marquardt, W.; Buechs, J.; Spiess, A.C.
Mechanistic kinetic model for symmetric carboligations using benzaldehyde lyase
Biotechnol. Bioeng.
101
27-38
2008
Pseudomonas fluorescens
Oelceroglu, A.H.; Calik, P.; Yilmaz, L.
Development of enhanced ultrafiltration methodologies for the resolution of racemic benzoin
J. Membr. Sci.
322
446-452
2008
Escherichia coli
-
Calik, P.; Levent, H.
Effects of pulse feeding of beet molasses on recombinant benzaldehyde lyase production by Escherichia coli BL21(DE3)
Appl. Microbiol. Biotechnol.
85
65-73
2009
synthetic construct
Schmidt, T.; Zavrel, M.; Spiess, A.; Ansorge-Schumacher, M.B.
Biochemical peculiarities of benzaldehyde lyase from Pseudomonas fluorescens Biovar I in the dependency on pH and cosolvent concentration
Bioorg. Chem.
37
84-89
2009
Pseudomonas fluorescens
Kaya-Celiker, H.; Angardi, V.; Calik, P.
Regulatory effects of oxygen transfer on overexpression of recombinant benzaldehyde lyase production by Escherichia coli BL21 (DE3)
Biotechnol. J.
4
1066-1076
2009
synthetic construct
Mikolajek, R.J.; Spiess, A.C.; Pohl, M.; Buechs, J.
Propioin synthesis using thiamine diphosphate-dependent enzymes
Biotechnol. Prog.
25
132-138
2009
Pseudomonas fluorescens
Brandt, G.S.; Kneen, M.M.; Petsko, G.A.; Ringe, D.; McLeish, M.J.
Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition
J. Am. Chem. Soc.
132
438-439
2010
Pseudomonas fluorescens
Calik, P.; Levent, H.
Effects of pretreated beet molasses on benzaldehyde lyase production by recombinant Escherichia coli BL21(DE3)pLySs
J. Appl. Microbiol.
107
1536-1541
2009
synthetic construct
Wiemann, L.O.; Buthe, A.; Klein, M.; van den Wittenboer, A.; Daehne, L.; Ansorge-Schumacher, M.B.
Encapsulation of synthetically valuable biocatalysts into polyelectrolyte multilayer systems
Langmuir
25
618-623
2009
Pseudomonas fluorescens
Sopaci, S.B.; Simsek, I.; Tural, B.; Volkan, M.; Demir, A.S.
Carboligation reactions with benzaldehyde lyase immobilized on superparamagnetic solid support
Org. Biomol. Chem.
7
1658-1664
2009
synthetic construct
Natalia, D.; Kohlmann, C.; Ansorge-Schumacher, M.B.; Greiner, L.
Direct spectrophotometric assay for benzaldehyde lyase activity
Biotechnol. Res. Int.
2011
478925
2011
Pseudomonas fluorescens
Van Den Wittenboer, A.; Niemeijer, B.; Karmee, S.; Ansorge-Schumacher, M.
Systematic assessment of the stability of benzaldehyde lyase in aqueous-organic biphasic systems and its stabilization by modification with methoxy-poly(ethylene) glycol
J. Mol. Catal. B
67
208-213
2010
Pseudomonas fluorescens
-
Mueller, C.R.; Perez-Sanchez, M.; Dominguez de Maria, P.
Benzaldehyde lyase-catalyzed diastereoselective C-C bond formation by simultaneous carboligation and kinetic resolution
Org. Biomol. Chem.
11
2000-2004
2013
Pseudomonas fluorescens (P51853)
Hernandez, K.; Parella, T.; Petrillo, G.; Uson, I.; Wandtke, C.M.; Joglar, J.; Bujons, J.; Clapes, P.
Intramolecular benzoin reaction catalyzed by benzaldehyde lyase from Pseudomonas fluorescens biovar I
Angew. Chem. Int. Ed. Engl.
56
5304-5307
2017
Pseudomonas fluorescens
Zhang, J.; Sheng, X.; Hou, Q.; Liu, Y.
Theoretical investigation on the dissociation of (R)-benzoin catalyzed by benzaldehyde lyase
Int. J. Quantum Chem.
114
375-382
2014
Pseudomonas fluorescens (P51853)
Maugeri, Z.; Dominguez De Maria, P.
Benzaldehyde lyase (BAL)-catalyzed enantioselective CC bond formation in deep-eutectic-solvents-buffer mixtures
J. Mol. Catal. B
107
120-123
2014
Pseudomonas fluorescens (P51853)
-
Peng, M.; Siebert, D.L.; Engqvist, M.K.M.; Niemeyer, C.M.; Rabe, K.S.
Modeling-assisted design of thermostable benzaldehyde lyases from Rhodococcus erythropolis for continuous production of alpha-hydroxy ketones
Chembiochem
23
e202100468
2021
Rhodococcus erythropolis, Pseudomonas fluorescens (P51853), Rhodococcus erythropolis R138
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