Reference on EC 4.1.2.27 - sphinganine-1-phosphate aldolase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Stoffel, W.; Lekim, D; Stich, G.
Distribution and properties of dihydrosphingosine-1-phosphate aldolase (Sphinganine-1-phosphate alkanal-lyase)
Hoppe-Seyler's Z. Physiol. Chem.
350
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1969
Bos taurus, Wickerhamomyces ciferrii, Rattus norvegicus, Sus scrofa
Shimojo, T.; Akino, T.; Miura, Y.; Schroepfer, G.J
Shingolipid base metabolism
J. Biol. Chem.
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1976
Rattus norvegicus
Shimojo, T; Schroepfer, Jr., G.J.
Sphingolipid base metabolism Sphinganine-1-phosphate lyase: Identification of ethanolamine 1-phosphate as product
Biochim. Biophys. Acta
431
433-446
1976
Rattus norvegicus
Stoffel, W.; Grol, M.
Chemistry and biochemistry of 1-desoxysphinganine 1-phosphonate (dihydrosphingosine-1-phosphonate)
Chem. Phys. Lipids
13
372-388
1974
Rattus norvegicus, Tetrahymena pyriformis
Stoffel, W.; Assmann, G.
Degradation in vitro of phytosphingosine (4D-Hydroxysphinganine)
Hoppe-Seyler's Z. Physiol. Chem.
353
965-970
1972
Rattus norvegicus
Akino, T.; Shimojo, Y.; Schroepfer, Jr., G.J.
Stereospecificity of proton uptake in the enzymatic conversion of sphinganine 1-phosphate to ethanolamine 1-phosphate
J. Am. Chem. Soc.
96
939-940
1974
Rattus norvegicus
Van Veldhoven, P.P.; Mannaerts, G.P
Subcellular localisation and membrane topology of sphingosine-1-phosphate lyase in rat liver
J. Biol. Chem.
266
12502-12507
1991
Rattus norvegicus
Van Veldhoven, P.P.
Sphingosine-phosphate lyase
Adv. Lipid Res.
26
69-98
1993
Canis lupus familiaris, Cavia porcellus, Homo sapiens, Platyrrhini, Mus musculus, Rattus norvegicus, Sus scrofa, Tetrahymena pyriformis
Van Veldhoven, P.P.; Mannaerts, G.P.
Sphinganine 1-phosphate metabolism in cultured skin fibroblasts: evidence for the existence of a sphingosine phosphatase
Biochem. J.
299
597-601
1994
Canis lupus familiaris, Homo sapiens
Saba, J.D.; Nara, F.; Bielawska, A.; Garrett, S.; Hannun, Y.A.
The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase
J. Biol. Chem.
272
26087-26090
1997
Saccharomyces cerevisiae
Zhou, J.; Saba, J.D.
Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast
Biochem. Biophys. Res. Commun.
242
502-507
1998
Mus musculus (Q8R0X7), Mus musculus
Van Veldhoven, P.P.; Gijsbers, S.; Mannaerts, G.P.; Vermeesch, J.R.; Brys, V.
Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q221
Biochim. Biophys. Acta
1487
128-134
2000
Homo sapiens (O95470), Homo sapiens
Li, G.; Foote, C.; Alexander, S.; Alexander, H.
Sphingosine-1-phosphate lyase has a central role in the development of Dictyostelium discoideum
Development
128
3473-3483
2001
Dictyostelium discoideum (Q54RV9), Dictyostelium discoideum
Kihara, A.; Ikeda, M.; Kariya, Y.; Lee, E.Y.; Lee, Y.M.; Igarashi, Y.
Sphingosine-1-phosphate lyase is involved in the differentiation of F9 embryonal carcinoma cells to primitive endoderm
J. Biol. Chem.
278
14578-14585
2003
Mus musculus
Mendel, J.; Heinecke, K.; Fyrst, H.; Saba, J.D.
Sphingosine phosphate lyase expression is essential for normal development in Caenorhabditis elegans
J. Biol. Chem.
278
22341-22349
2003
Caenorhabditis elegans
Reiss, U.; Oskouian, B.; Zhou, J.; Gupta, V.; Sooriyakumaran, P.; Kelly, S.; Wang, E.; Merrill, A.H., Jr.; Saba, J.D.
Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis
J. Biol. Chem.
279
1281-1290
2004
Homo sapiens (O95470), Homo sapiens
Van Veldhoven, P.P.
Sphingosine-1-phosphate lyase
Methods Enzymol.
311
244-254
2000
Homo sapiens, Mammalia, Mus musculus, Rattus norvegicus, Tetrahymena pyriformis
Ikeda, M.; Kihara, A.; Igarashi, Y.
Sphingosine-1-phosphate lyase SPL is an endoplasmic reticulum-resident, integral membrane protein with the pyridoxal 5'-phosphate binding domain exposed to the cytosol
Biochem. Biophys. Res. Commun.
325
338-343
2004
Mus musculus
Ikeda, M.; Kihara, A.; Kariya, Y.; Lee, Y.M.; Igarashi, Y.
Sphingolipid-to-glycerophospholipid conversion in SPL-null cells implies the existence of an alternative isozyme
Biochem. Biophys. Res. Commun.
329
474-479
2005
Mus musculus
Bandhuvula, P.; Tam, Y.Y.; Oskouian, B.; Saba, J.D.
The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity
J. Biol. Chem.
280
33697-33700
2005
Homo sapiens, Mus musculus
Min, J.; Van Veldhoven, P.P.; Zhang, L.; Hanigan, M.H.; Alexander, H.; Alexander, S.
Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner
Mol. Cancer Res.
3
287-296
2005
Homo sapiens
Kim, D.H.; Lee, Y.S.; Lee, Y.M.; Oh, S.; Yun, Y.P.; Yoo, H.S.
Elevation of sphingoid base 1-phosphate as a potential contributor to hepatotoxicity in fumonisin B1-exposed mice
Arch. Pharm. Res.
30
962-969
2007
Mus musculus
Miyazaki, Y.; Hiraide, M.; Shibuya, H.
Molecular cloning of functional genes for high growth-temperature and salt tolerance of the basidiomycete Fomitopsis pinicola isolated in a mangrove forest in Micronesia
Biosci. Biotechnol. Biochem.
71
273-278
2007
Fomitopsis pinicola, Fomitopsis pinicola 130-2
Peest, U.; Sensken, S.C.; Andreani, P.; Haenel, P.; Van Veldhoven, P.P.; Graeler, M.H.
S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake
J. Cell. Biochem.
104
756-772
2008
Homo sapiens
Niu, Y.; Chen, K.; Wang, J.; Liu, X.; Qin, H.; Zhang, A.; Wang, D.
Molecular and functional characterization of sphingosine-1-phosphate lyase homolog from higher plants
J. Integr. Plant Biol.
49
323-335
2007
Oryza sativa, Arabidopsis thaliana (Q9C509)
-
Bandhuvula, P.; Fyrst, H.; Saba, J.D.
A rapid fluorescence assay for sphingosine-1-phosphate lyase enzyme activity
J. Lipid Res.
48
2769-2778
2007
Homo sapiens, Mus musculus
Oskouian, B.; Sooriyakumaran, P.; Borowsky, A.D.; Crans, A.; Dillard-Telm, L.; Tam, Y.Y.; Bandhuvula, P.; Saba, J.D.
Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer
Proc. Natl. Acad. Sci. USA
103
17384-17389
2006
Homo sapiens, Mus musculus
Bandhuvula, P.; Saba, J.D.
Sphingosine-1-phosphate lyase in immunity and cancer: silencing the siren
Trends Mol. Med.
13
210-217
2007
Caenorhabditis elegans, Dictyostelium discoideum, Drosophila melanogaster, Homo sapiens, Leishmania major, Mus musculus, Rattus norvegicus
Mukhopadhyay, D.; Howell, K.S.; Riezman, H.; Capitani, G.
Identifying key residues of sphinganine-1-phosphate lyase for function in vivo and in vitro
J. Biol. Chem.
283
20159-20169
2008
Saccharomyces cerevisiae (Q05567)
Colie, S.; Codogno, P.; Levade, T.; Andrieu-Abadie, N.
Regulation of cell death by sphingosine 1-phosphate lyase
Autophagy
6
426-427
2010
Mus musculus
Bandhuvula, P.; Li, Z.; Bittman, R.; Saba, J.D.
Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate
Biochem. Biophys. Res. Commun.
380
366-370
2009
Homo sapiens
Dunlap, K.A.; Kwak, H.I.; Burghardt, R.C.; Bazer, F.W.; Magness, R.R.; Johnson, G.A.; Bayless, K.J.
The sphingosine 1-phosphate (S1P) signaling pathway is regulated during pregnancy in sheep
Biol. Reprod.
82
876-887
2010
Ovis aries
Claas, R.F.; ter Braak, M.; Hegen, B.; Hardel, V.; Angioni, C.; Schmidt, H.; Jakobs, K.H.; Van Veldhoven, P.P.; zu Heringdorf, D.M.
Enhanced Ca2+ storage in sphingosine-1-phosphate lyase-deficient fibroblasts
Cell. Signal.
22
476-483
2010
Mus musculus
Ling, B.; Chen, L.; Alcorn, J.; Ma, B.; Yang, J.
Sphingosine-1-phosphate: a potential therapeutic agent against human breast cancer
Invest. New Drugs
29
396-399
2009
Homo sapiens
Hagen, N.; Van Veldhoven, P.P.; Proia, R.L.; Park, H.; Merrill, A.H.; van Echten-Deckert, G.
Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons
J. Biol. Chem.
284
11346-11353
2009
Mus musculus
Bektas, M.; Allende, M.L.; Lee, B.G.; Chen, W.; Amar, M.J.; Remaley, A.T.; Saba, J.D.; Proia, R.L.
Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver
J. Biol. Chem.
285
10880-10889
2010
Mus musculus
Weber, C.; Krueger, A.; Muenk, A.; Bode, C.; Van Veldhoven, P.P.; Graeler, M.H.
Discontinued postnatal thymocyte development in sphingosine 1-phosphate-lyase-deficient mice
J. Immunol.
183
4292-4301
2009
Mus musculus
Bagdanoff, J.T.; Donoviel, M.S.; Nouraldeen, A.; Tarver, J.; Fu, Q.; Carlsen, M.; Jessop, T.C.; Zhang, H.; Hazelwood, J.; Nguyen, H.; Baugh, S.D.; Gardyan, M.; Terranova, K.M.; Barbosa, J.; Yan, J.; Bednarz, M.; Layek, S.; Courtney, L.F.; Taylor, J.; Digeorge-Foushee, A.M.; Gopinathan, S.; Bruce, D.; Smi, S.m.i.t.
Inhibition of sphingosine-1-phosphate lyase for the treatment of autoimmune disorders
J. Med. Chem.
52
3941-3953
2009
Mus musculus
Vogel, P.; Donoviel, M.S.; Read, R.; Hansen, G.M.; Hazlewood, J.; Anderson, S.J.; Sun, W.; Swaffield, J.; Oravecz, T.
Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions
PLoS ONE
4
e4112
2009
Homo sapiens, Mus musculus (Q8R0X7), Mus musculus
Yu, X.Q.; Kramer, J.; Moran, L.; ONeill, E.; Nouraldeen, A.; Oravecz, T.; Wilson, A.G.
Pharmacokinetic/pharmacodynamic modelling of 2-acetyl-4(5)-tetrahydroxybutyl imidazole-induced peripheral lymphocyte sequestration through increasing lymphoid sphingosine 1-phosphate
Xenobiotica
40
350-356
2010
Rattus norvegicus
Serra, M.; Saba, J.
Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function
Adv. Enzyme Regul.
50
349-362
2010
Homo sapiens, Rattus norvegicus, Mus musculus (Q8R0X7)
Bandhuvula, P.; Honbo, N.; Wang, G.Y.; Jin, Z.Q.; Fyrst, H.; Zhang, M.; Borowsky, A.D.; Dillard, L.; Karliner, J.S.; Saba, J.D.
S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart
Am. J. Physiol. Heart Circ. Physiol.
300
H1753-H1761
2011
Mus musculus
Berdyshev, E.V.; Goya, J.; Gorshkova, I.; Prestwich, G.D.; Byun, H.S.; Bittman, R.; Natarajan, V.
Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization-liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal
Anal. Biochem.
408
12-18
2011
Mus musculus
Ito, H.; Yoshida, K.; Murakami, M.; Hagiwara, K.; Sasaki, N.; Kobayashi, M.; Takagi, A.; Kojima, T.; Sobue, S.; Suzuki, M.; Tamiya-Koizumi, K.; Nakamura, M.; Banno, Y.; Nozawa, Y.; Murate, T.
Heterogeneous sphingosine-1-phosphate lyase gene expression and its regulatory mechanism in human lung cancer cell lines
Biochim. Biophys. Acta
1811
119-128
2011
Homo sapiens
Kumar, A.; Oskouian, B.; Fyrst, H.; Zhang, M.; Paris, F.; Saba, J.D.
S1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism
Cell Death Dis.
2
e119
2011
Mus musculus
Berdyshev, E.V.; Gorshkova, I.; Usatyuk, P.; Kalari, S.; Zhao, Y.; Pyne, N.J.; Pyne, S.; Sabbadini, R.A.; Garcia, J.G.; Natarajan, V.
Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase
PLoS ONE
6
e16571
2011
Homo sapiens
Huwiler, A.; Bourquin, F.; Kotelevets, N.; Pastukhov, O.; Capitani, G.; Gruetter, M.G.; Zangemeister-Wittke, U.
A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders
PLoS ONE
6
e22436
2011
Symbiobacterium thermophilum
Bourquin, F.; Capitani, G.; Gruetter, M.G.
PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism
Protein Sci.
20
1492-1508
2011
Saccharomyces cerevisiae, Homo sapiens, Myxococcus xanthus, Symbiobacterium thermophilum
Bourquin, F.; Riezman, H.; Capitani, G.; Gruetter, M.G.
Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism
Structure
18
1054-1065
2010
Saccharomyces cerevisiae, Homo sapiens (O95470), Homo sapiens, Symbiobacterium thermophilum (Q67PY4), Symbiobacterium thermophilum
Billich, A.; Beerli, C.; Bergmann, R.; Bruns, C.; Loetscher, E.
Cellular assay for the characterization of sphingosine-1-phosphate lyase inhibitors
Anal. Biochem.
434
247-253
2013
Homo sapiens
Smith, G.S.; Kumar, A.; Saba, J.D.
Sphingosine phosphate lyase regulates murine embryonic stem cell proliferation and pluripotency through an S1P2/STAT3 signaling pathway
Biomolecules
3
351-368
2013
Mus musculus
Gatfield, J.; Monnier, L.; Studer, R.; Bolli, M.H.; Steiner, B.; Nayler, O.
Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling
Cell. Signal.
26
1576-1588
2014
Homo sapiens
Reina, E.; Camacho, L.; Casas, J.; Van Veldhoven, P.P.; Fabrias, G.
Determination of sphingosine-1-phosphate lyase activity by gas chromatography coupled to electron impact mass spectrometry
Chem. Phys. Lipids
165
225-231
2012
Mus musculus
Park, S.M.; Angel, C.E.; McIntosh, J.D.; Brooks, A.E.; Middleditch, M.; Chen, C.J.; Ruggiero, K.; Cebon, J.; Dunbar, P.R.
Sphingosine-1-phosphate lyase is expressed by CD68(+) cells on the parenchymal side of marginal reticular cells in human lymph nodes
Eur. J. Immunol.
44
2425-2436
2014
Homo sapiens
de la Garza-Rodea, A.S.; Baldwin, D.M.; Oskouian, B.; Place, R.F.; Bandhuvula, P.; Kumar, A.; Saba, J.D.
Sphingosine phosphate lyase regulates myogenic differentiation via S1P receptor-mediated effects on myogenic microRNA expression
FASEB J.
28
506-519
2014
Mus musculus (Q8R0X7), Mus musculus
Borowsky, A.D.; Bandhuvula, P.; Kumar, A.; Yoshinaga, Y.; Nefedov, M.; Fong, L.G.; Zhang, M.; Baridon, B.; Dillard, L.; de Jong, P.; Young, S.G.; West, D.B.; Saba, J.D.
Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues
J. Lipid Res.
53
1920-1931
2012
Mus musculus
Brizuela, L.; Ader, I.; Mazerolles, C.; Bocquet, M.; Malavaud, B.; Cuvillier, O.
First evidence of sphingosine 1-phosphate lyase protein expression and activity downregulation in human neoplasm: implication for resistance to therapeutics in prostate cancer
Mol. Cancer Ther.
11
1841-1851
2012
Homo sapiens
Billich, A.; Baumruker, T.; Beerli, C.; Bigaud, M.; Bruns, C.; Calzascia, T.; Isken, A.; Kinzel, B.; Loetscher, E.; Metzler, B.; Mueller, M.; Nuesslein-Hildesheim, B.; Kleylein-Sohn, B.
Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis
PLoS ONE
8
e59630
2013
Mus musculus
Ceccom, J.; Loukh, N.; Lauwers-Cances, V.; Touriol, C.; Nicaise, Y.; Gentil, C.; Uro-Coste, E.; Pitson, S.; Maurage, C.A.; Duyckaerts, C.; Cuvillier, O.; Delisle, M.B.
Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimers disease
Acta Neuropathol. Commun.
2
12
2014
Homo sapiens
Dinges, J.; Harris, C.M.; Wallace, G.A.; Argiriadi, M.A.; Queeney, K.L.; Perron, D.C.; Dominguez, E.; Kebede, T.; Desino, K.E.; Patel, H.; Vasudevan, A.
Hit-to-lead evaluation of a novel class of sphingosine 1-phosphate lyase inhibitors
Bioorg. Med. Chem. Lett.
26
2297-2302
2016
Homo sapiens
Sanllehi, P.; Casasampere, M.; Abad, J.L.; Fabrias, G.; Lopez, O.; Bujons, J.; Casas, J.; Delgado, A.
The first fluorogenic sensor for sphingosine-1-phosphate lyase activity in intact cells
Chem. Commun. (Camb.)
53
5441-5444
2017
Homo sapiens (O95470)
Suh, J.H.; Eltanawy, A.; Rangan, A.; Saba, J.D.
A facile stable-isotope dilution method for determination of sphingosine phosphate lyase activity
Chem. Phys. Lipids
194
101-109
2016
Homo sapiens, Mus musculus
Sanllehi, P.; Abad, J.L.; Casas, J.; Delgado, A.
Inhibitors of sphingosine-1-phosphate metabolism (sphingosine kinases and sphingosine-1-phosphate lyase)
Chem. Phys. Lipids
197
69-81
2016
Homo sapiens
Sanllehi, P.; Abad, J.L.; Bujons, J.; Casas, J.; Delgado, A.
Studies on the inhibition of sphingosine-1-phosphate lyase by stabilized reaction intermediates and stereodefined azido phosphates
Eur. J. Med. Chem.
123
905-915
2016
Homo sapiens, Symbiobacterium thermophilum
Hahn, C.; Tyka, K.; Saba, J.D.; Lenzen, S.; Gurgul-Convey, E.
Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity
J. Biol. Chem.
292
20292-20304
2017
Rattus norvegicus
Zamora-Pineda, J.; Kumar, A.; Suh, J.H.; Zhang, M.; Saba, J.D.
Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress
J. Exp. Med.
213
2773-2791
2016
Mus musculus
McLean, C.J.; Marles-Wright, J.; Custodio, R.; Lowther, J.; Kennedy, A.J.; Pollock, J.; Clarke, D.J.; Brown, A.R.; Campopiano, D.J.
Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei
J. Lipid Res.
58
137-150
2017
Burkholderia pseudomallei (Q63IP8), Burkholderia pseudomallei, Burkholderia pseudomallei K96243 (Q63IP8), Burkholderia pseudomallei K96243
Weiler, S.; Braendlin, N.; Beerli, C.; Bergsdorf, C.; Schubart, A.; Srinivas, H.; Oberhauser, B.; Billich, A.
Orally active 7-substituted [(4-benzylphthalazin-1-yl)-2-methylpiperazin-1-yl]nicotinonitriles as active-site inhibitors of sphingosine 1-phosphate lyase for the treatment of multiple sclerosis
J. Med. Chem.
57
5074-5084
2014
Homo sapiens (O95470), Homo sapiens
Ohtoyo, M.; Tamura, M.; Machinaga, N.; Muro, F.; Hashimoto, R.
Sphingosine 1-phosphate lyase inhibition by 2-acetyl-4-(tetrahydroxybutyl)imidazole (THI) under conditions of vitamin B6 deficiency
Mol. Cell. Biochem.
400
125-133
2015
Mus musculus
Custodio, R.; McLean, C.J.; Scott, A.E.; Lowther, J.; Kennedy, A.; Clarke, D.J.; Campopiano, D.J.; Sarkar-Tyson, M.; Brown, A.R.
Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei
Mol. Microbiol.
102
1004-1019
2016
Burkholderia pseudomallei, Burkholderia thailandensis, Burkholderia pseudomallei K96243
Zhang, H.; Jin, X.; Huang, L.; Hong, Y.; Zhang, Y.; Ouyang, Z.; Li, X.; Song, F.; Li, D.
Molecular characterization of rice sphingosine-1-phosphate lyase gene OsSPL1 and functional analysis of its role in disease resistance response
Plant Cell Rep.
33
1745-1756
2014
Oryza sativa
Abu Khweek, A.; Kanneganti, A.; Guttridge D, D.C.; Amer, A.O.
The sphingosine-1-phosphate lyase (LegS2) contributes to the restriction of Legionella pneumophila in murine macrophages
PLoS ONE
11
e0146410
2016
Legionella pneumophila, Legionella pneumophila JR32
Schuemann, J.; Grevot, A.; Ledieu, D.; Wolf, A.; Schubart, A.; Piaia, A.; Sutter, E.; Cote, S.; Beerli, C.; Pognan, F.; Billich, A.; Moulin, P.; Walker, U.J.
Reduced activity of sphingosine-1-phosphate lyase induces podocyte-related glomerular proteinuria, skin irritation, and platelet activation
Toxicol. Pathol.
43
694-703
2015
Mus musculus, Rattus norvegicus
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